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Human Microbiome Project

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Questions and Answers

What was the aim of the first phase of the Human Microbiome Project?

To identify a healthy microbiome and variations in different diseases (correct)

To study the genetic aspects of microorganisms

To investigate the interactions between the human body and the microbiome

To map all life forms on and in the human body

What did the research show about microbiome profiles?

Microbiome profiles do not vary between different populations

Microbiome profiles remain constant throughout an individual's lifetime

Different individuals have different microbiome profiles (correct)

Microbiome profiles are largely determined by genetics

How can changes in the microbiome affect drug performance?

They only affect drugs used for treating autism

They have no effect on drug performance

They can affect how well certain drugs perform, such as those used to treat heart conditions (correct)

They can only affect drugs used for treating cancer

What is the focus of the second phase of the Human Microbiome Project?

<p>Investigating how the body and the microbiome interact to influence areas such as immunity and metabolism</p> Signup and view all the answers

What did the Human Microbiome Project reveal about microbiome profiles and their acquisition?

<p>Profiles are largely acquired early in life, but can change rapidly in certain circumstances</p> Signup and view all the answers

Study Notes

Human Microbiome Project

The first phase aimed to create a reference set of microbial genome sequences from different body sites to understand the diversity of the human microbiome.

Research Findings

The research showed that microbiome profiles vary greatly between individuals and even within an individual over time.

Microbiome and Drug Performance

Changes in the microbiome can affect drug performance, as certain bacteria can metabolize or interact with drugs, altering their efficacy.

Second Phase of the Human Microbiome Project

The second phase focuses on understanding the role of the microbiome in various diseases, such as inflammatory bowel disease and type 2 diabetes.

Microbiome Acquisition and Development

The Human Microbiome Project revealed that microbiome profiles are shaped by early-life exposures, such as delivery mode (vaginal vs. cesarean section) and infant feeding practices (breastfeeding vs. formula).

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Description

Learn about the Human Microbiome Project and its aim to map the microorganisms living in and on the human body. Discover the research findings and the variations in different types of diseases.