Human Histology and Biopsies

The study of microscopic structures of biological materials from humans and their functional relationships.

Preparation of tissue samples for microscopic examination to diagnose diseases.

A method where a small sample of skin is removed using a special tool to diagnose skin conditions.

A biopsy method that removes the outer layers of the skin with a blade to examine skin lesions.

A type of biopsy where the entire lump or mass is removed.

A type of biopsy where only a small portion of a lump is removed for examination.

The process of preparing tissue samples for examination by permanently preserving, staining, and mounting them on slides.

A method of tissue preparation where a thin slice of tissue is frozen and examined under a microscope.

A technique where cells from the bone marrow are obtained using a large needle and examined under a microscope.

The process where the tissue is made translucent by replacing the alcohol or dehydrating agent with a substance that makes the tissue more transparent and ready for embedding in paraffin or other embedding media.

This process involves completely replacing the clearing agent with liquid paraffin (or another embedding medium) for proper tissue support during sectioning.

This is the final step in preparing the tissue for viewing under a microscope. The tissue is stained with dyes to enhance its visibility and highlight specific structures.

This technique uses dyes to differentiate various types of tissue based on their chemical composition.

This method uses dyes to distinguish different parts of the tissue based on their structure and properties.

A biopsy technique involving a thin needle to collect a sample of cells. It's less invasive than core biopsy.

A biopsy technique where a core of tissue is extracted using a larger needle. It's often guided by ultrasound or MRI for precision.

A procedure using a flexible tube with a light and camera to visualize internal organs and collect tissue samples. It's used for diagnosing various conditions.

The process of preserving tissues for microscopic examination. It involves treating samples with chemicals to prevent decay and distortion.

The most critical step in histopathology, where tissues are stabilized and prepared for microscopic examination.

A commonly used chemical for tissue fixation, it helps preserve the morphology and chemical integrity of the tissue.

The preservation of tissue morphology and chemical integrity, enabling an accurate representation of the tissue structure.

To harden and protect the tissue from damage during further processing. It allows handling and cutting the tissue without degradation.

A process used in tissue preparation for microscopic examination to preserve the tissue's structure and prevent decomposition.

A chemical solution used to preserve the tissue's structure during the biopsy process.

A common type of fixative solution used in tissue preparation, known for its ability to preserve cellular structures and proteins.

A process involved in tissue preparation that removes water from the tissue following fixation, preparing it for embedding in wax.

A method used to remove calcium from bone or teeth samples to allow for proper embedding and sectioning.

A process used to remove water from the tissue following fixation, preparing it for embedding in wax.

A process of embedding tissue in a solid medium like wax or plastic, allowing it to be sliced into thin sections for microscopic examination.

The process of infiltrating tissue with a medium, usually wax, to solidify it and make it easier to cut into thin sections for microscopic examination.

A substance that is used to remove the clearing agent from tissues during tissue processing. It helps to dissolve the clearing agent and prepare the tissue for embedding in wax.

A type of impregnation that uses paraffin wax to solidify the tissue. It's the most common method used for routine tissue processing.

A type of impregnation that uses a purified form of nitrocellulose to solidify the tissue. It's suitable for specimens with large hollows or cavities.

The process of mounting a tissue section onto a slide with a mounting medium, which helps to preserve the section and make it easier to observe under a microscope.

A substance that is used to attach a tissue section to a slide after staining. It helps to preserve and protect the section.

When tissue substances with a net negative charge, like DNA and RNA, react strongly with hematoxylin, a basic dye, they are considered ‘basophilic’.