Human Growth Hormone Functions Quiz

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Which hormone has direct effects on peripheral target cells and stimulates the secretion of IGF-1 by the liver?

Insulin

Glucocorticoids

Growth Hormone (GH) (correct)

Somatostatin

What is the primary factor that suppresses serum GH levels after meals high in glucose?

Ghrelin secretion

Insulin-induced hypoglycemia

Glucocorticoids

Glucose challenge (correct)

Which hormone acts at renal collecting ducts and increases water reabsorption through V2 receptors?

Oxytocin

Dopamine

Vasopressin (ADH) (correct)

IGF-1

What is a potent stimulus for vasopressin (ADH) release other than serum osmolality?

Hypovolemia Signup and view all the answers

Which hormone is responsible for uterine contraction and breast milk secretion?

Oxytocin Signup and view all the answers

Which substance is NOT mentioned as a stimulant for GH release in the text?

Insulin Signup and view all the answers

What is the primary effect of dopamine D2 receptor agonists on GH-secreting tumors?

Inhibit GH secretion Signup and view all the answers

Which hormone is synthesized in the liver and has direct effects on peripheral target cells?

IGF-1 Signup and view all the answers

Which hormone is primarily under inhibitory control by dopamine?

Prolactin Signup and view all the answers

What is the primary stimulatory factor for ACTH release?

CRH Signup and view all the answers

Which hormone is mainly under inhibitory control by somatostatin?

Growth Hormone Signup and view all the answers

Which is NOT a hormone primarily under trophic stimulation?

Prolactin Signup and view all the answers

Which hormone activation is less important for its control by somatostatin?

TSH Signup and view all the answers

What is the primary stimulatory factor for TSH release?

CRH Signup and view all the answers

Which hormone is primarily under trophic stimulation?

ACTH Signup and view all the answers

Which hormone activation is less important for its control by somatostatin?

FSH Signup and view all the answers

What is the LR+ for defining a goitre as a mass larger than the distal phalanx of the thumb in children?

3.0 Signup and view all the answers

What does an LR of 0.30 (95% CI 0.24-0.37) suggest about defining a goitre as a mass larger than the distal phalanx of the thumb?

Low accuracy Signup and view all the answers

What is an alternative method for diagnosing a goitre?

Measuring the size of the thyroid mass relative to the thumb Signup and view all the answers

What is indicated if a patient has a hot nodule on a radioisotope thyroid scan?

Low chance of malignancy Signup and view all the answers

When should a radioisotope thyroid scan (Technetium 99) be ordered as per the text?

When patient is thyrotoxic Signup and view all the answers

What does RAIU test measure according to the text?

Iodine turnover by the thyroid gland Signup and view all the answers

If a patient has low iodine uptake on RAIU test, what might this indicate?

Exogenous thyroid hormone use Signup and view all the answers

What should be done if concerning sonographic features are found after a thyroid ultrasound?

Further workup required Signup and view all the answers

Which of the following is a common adverse effect of thionamides?

Teratogenicity Signup and view all the answers

What is the mechanism of action of thionamides in inhibiting thyroid hormone synthesis?

Inhibiting peroxidase catalyzed reactions Signup and view all the answers

Which medication is preferred over propylthiouracil (PTU) due to a longer duration of action?

Methimazole (MMI) Signup and view all the answers

What should be monitored prior to considering treatment discontinuation with antithyroid medications?

TSH and TKAb levels Signup and view all the answers

Which condition is a good predictor for long-term remission with medical therapy using thionamides?

Small goitre Signup and view all the answers

When is it recommended to use propylthiouracil (PTU) during pregnancy?

First 16 weeks of pregnancy Signup and view all the answers

What are the major side effects associated with antithyroid medications?

Hepatotoxicity (cholestasis, hepatitis) Signup and view all the answers

What is the preferred treatment duration with antithyroid medications before considering treatment discontinuation for long-term remission?

12-18 months Signup and view all the answers

What is the etiologic classification of Type 1 Diabetes Mellitus according to the text?

Genetic defects of beta cell function Signup and view all the answers

Which of the following is NOT listed as a cause of Type 2 Diabetes Mellitus according to the text?

Infections Signup and view all the answers

Which of the following is NOT a genetic syndrome associated with Diabetes Mellitus according to the text?

Cystic fibrosis Signup and view all the answers

What is one of the drug-induced causes of Diabetes Mellitus mentioned in the text?

Thiazides Signup and view all the answers

Which condition is characterized by immune-mediated or idiopathic cell destruction leading to absolute insulin deficiency?

LADA Signup and view all the answers

What type of diabetes occurs when the body does not effectively use the insulin that is produced?

Type 2 Diabetes Mellitus Signup and view all the answers

Which disease related to the pancreas is listed as a potential cause of Diabetes Mellitus in the text?

Pancreatitis Signup and view all the answers

What is a common endocrinopathy associated with Diabetes Mellitus as per the text?

Acromegaly Signup and view all the answers

Human Growth Hormone Functions Quiz

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Questions and Answers

Which hormone has direct effects on peripheral target cells and stimulates the secretion of IGF-1 by the liver?

What is the primary factor that suppresses serum GH levels after meals high in glucose?

Which hormone acts at renal collecting ducts and increases water reabsorption through V2 receptors?

What is a potent stimulus for vasopressin (ADH) release other than serum osmolality?

Which hormone is responsible for uterine contraction and breast milk secretion?

Which substance is NOT mentioned as a stimulant for GH release in the text?

What is the primary effect of dopamine D2 receptor agonists on GH-secreting tumors?

Which hormone is synthesized in the liver and has direct effects on peripheral target cells?

Which hormone is primarily under inhibitory control by dopamine?

What is the primary stimulatory factor for ACTH release?

Which hormone is mainly under inhibitory control by somatostatin?

Which is NOT a hormone primarily under trophic stimulation?

Which hormone activation is less important for its control by somatostatin?

What is the primary stimulatory factor for TSH release?

Which hormone is primarily under trophic stimulation?

Which hormone activation is less important for its control by somatostatin?

What is the LR+ for defining a goitre as a mass larger than the distal phalanx of the thumb in children?

What does an LR of 0.30 (95% CI 0.24-0.37) suggest about defining a goitre as a mass larger than the distal phalanx of the thumb?

What is an alternative method for diagnosing a goitre?

What is indicated if a patient has a hot nodule on a radioisotope thyroid scan?

When should a radioisotope thyroid scan (Technetium 99) be ordered as per the text?

What does RAIU test measure according to the text?

If a patient has low iodine uptake on RAIU test, what might this indicate?

What should be done if concerning sonographic features are found after a thyroid ultrasound?

Which of the following is a common adverse effect of thionamides?

What is the mechanism of action of thionamides in inhibiting thyroid hormone synthesis?

Which medication is preferred over propylthiouracil (PTU) due to a longer duration of action?

What should be monitored prior to considering treatment discontinuation with antithyroid medications?

Which condition is a good predictor for long-term remission with medical therapy using thionamides?

When is it recommended to use propylthiouracil (PTU) during pregnancy?

What are the major side effects associated with antithyroid medications?

What is the preferred treatment duration with antithyroid medications before considering treatment discontinuation for long-term remission?

What is the etiologic classification of Type 1 Diabetes Mellitus according to the text?

Which of the following is NOT listed as a cause of Type 2 Diabetes Mellitus according to the text?

Which of the following is NOT a genetic syndrome associated with Diabetes Mellitus according to the text?

What is one of the drug-induced causes of Diabetes Mellitus mentioned in the text?

Which condition is characterized by immune-mediated or idiopathic cell destruction leading to absolute insulin deficiency?

What type of diabetes occurs when the body does not effectively use the insulin that is produced?

Which disease related to the pancreas is listed as a potential cause of Diabetes Mellitus in the text?

What is a common endocrinopathy associated with Diabetes Mellitus as per the text?

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