Human Growth Hormone Functions Quiz
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Questions and Answers

Which hormone has direct effects on peripheral target cells and stimulates the secretion of IGF-1 by the liver?

  • Insulin
  • Glucocorticoids
  • Growth Hormone (GH) (correct)
  • Somatostatin
  • What is the primary factor that suppresses serum GH levels after meals high in glucose?

  • Ghrelin secretion
  • Insulin-induced hypoglycemia
  • Glucocorticoids
  • Glucose challenge (correct)
  • Which hormone acts at renal collecting ducts and increases water reabsorption through V2 receptors?

  • Oxytocin
  • Dopamine
  • Vasopressin (ADH) (correct)
  • IGF-1
  • What is a potent stimulus for vasopressin (ADH) release other than serum osmolality?

    <p>Hypovolemia</p> Signup and view all the answers

    Which hormone is responsible for uterine contraction and breast milk secretion?

    <p>Oxytocin</p> Signup and view all the answers

    Which substance is NOT mentioned as a stimulant for GH release in the text?

    <p>Insulin</p> Signup and view all the answers

    What is the primary effect of dopamine D2 receptor agonists on GH-secreting tumors?

    <p>Inhibit GH secretion</p> Signup and view all the answers

    Which hormone is synthesized in the liver and has direct effects on peripheral target cells?

    <p>IGF-1</p> Signup and view all the answers

    Which hormone is primarily under inhibitory control by dopamine?

    <p>Prolactin</p> Signup and view all the answers

    What is the primary stimulatory factor for ACTH release?

    <p>CRH</p> Signup and view all the answers

    Which hormone is mainly under inhibitory control by somatostatin?

    <p>Growth Hormone</p> Signup and view all the answers

    Which is NOT a hormone primarily under trophic stimulation?

    <p>Prolactin</p> Signup and view all the answers

    Which hormone activation is less important for its control by somatostatin?

    <p>TSH</p> Signup and view all the answers

    What is the primary stimulatory factor for TSH release?

    <p>CRH</p> Signup and view all the answers

    Which hormone is primarily under trophic stimulation?

    <p>ACTH</p> Signup and view all the answers

    Which hormone activation is less important for its control by somatostatin?

    <p>FSH</p> Signup and view all the answers

    What is the LR+ for defining a goitre as a mass larger than the distal phalanx of the thumb in children?

    <p>3.0</p> Signup and view all the answers

    What does an LR of 0.30 (95% CI 0.24-0.37) suggest about defining a goitre as a mass larger than the distal phalanx of the thumb?

    <p>Low accuracy</p> Signup and view all the answers

    What is an alternative method for diagnosing a goitre?

    <p>Measuring the size of the thyroid mass relative to the thumb</p> Signup and view all the answers

    What is indicated if a patient has a hot nodule on a radioisotope thyroid scan?

    <p>Low chance of malignancy</p> Signup and view all the answers

    When should a radioisotope thyroid scan (Technetium 99) be ordered as per the text?

    <p>When patient is thyrotoxic</p> Signup and view all the answers

    What does RAIU test measure according to the text?

    <p>Iodine turnover by the thyroid gland</p> Signup and view all the answers

    If a patient has low iodine uptake on RAIU test, what might this indicate?

    <p>Exogenous thyroid hormone use</p> Signup and view all the answers

    What should be done if concerning sonographic features are found after a thyroid ultrasound?

    <p>Further workup required</p> Signup and view all the answers

    Which of the following is a common adverse effect of thionamides?

    <p>Teratogenicity</p> Signup and view all the answers

    What is the mechanism of action of thionamides in inhibiting thyroid hormone synthesis?

    <p>Inhibiting peroxidase catalyzed reactions</p> Signup and view all the answers

    Which medication is preferred over propylthiouracil (PTU) due to a longer duration of action?

    <p>Methimazole (MMI)</p> Signup and view all the answers

    What should be monitored prior to considering treatment discontinuation with antithyroid medications?

    <p>TSH and TKAb levels</p> Signup and view all the answers

    Which condition is a good predictor for long-term remission with medical therapy using thionamides?

    <p>Small goitre</p> Signup and view all the answers

    When is it recommended to use propylthiouracil (PTU) during pregnancy?

    <p>First 16 weeks of pregnancy</p> Signup and view all the answers

    What are the major side effects associated with antithyroid medications?

    <p>Hepatotoxicity (cholestasis, hepatitis)</p> Signup and view all the answers

    What is the preferred treatment duration with antithyroid medications before considering treatment discontinuation for long-term remission?

    <p>12-18 months</p> Signup and view all the answers

    What is the etiologic classification of Type 1 Diabetes Mellitus according to the text?

    <p>Genetic defects of beta cell function</p> Signup and view all the answers

    Which of the following is NOT listed as a cause of Type 2 Diabetes Mellitus according to the text?

    <p>Infections</p> Signup and view all the answers

    Which of the following is NOT a genetic syndrome associated with Diabetes Mellitus according to the text?

    <p>Cystic fibrosis</p> Signup and view all the answers

    What is one of the drug-induced causes of Diabetes Mellitus mentioned in the text?

    <p>Thiazides</p> Signup and view all the answers

    Which condition is characterized by immune-mediated or idiopathic cell destruction leading to absolute insulin deficiency?

    <p>LADA</p> Signup and view all the answers

    What type of diabetes occurs when the body does not effectively use the insulin that is produced?

    <p>Type 2 Diabetes Mellitus</p> Signup and view all the answers

    Which disease related to the pancreas is listed as a potential cause of Diabetes Mellitus in the text?

    <p>Pancreatitis</p> Signup and view all the answers

    What is a common endocrinopathy associated with Diabetes Mellitus as per the text?

    <p>Acromegaly</p> Signup and view all the answers

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