6 Questions
What did the completion of the Human Genome Project mark?
The beginning of a new era in biomedical sciences
What new information did the first curated version of the Human Genome Project provide in 2004?
A sequence-based map of the normal human genome
What did the construction of the HapMap, which contains single nucleotide polymorphisms, and the underlying genomic structure of natural human genomic variation, allow?
An extraordinary throughput in cataloging somatic mutations in cancer
What was the goal that became within reach of the scientific community for the first time?
The identification of all the genetic changes associated with a human cancer
Before the elucidation of the human genome, how were several cancer genes, such as KRAS, TP53, and APC, successfully discovered?
Using approaches based on an oncovirus analysis, linkage studies, LOH, and cytogenetics
What new opportunity did the Human Genome Project and HapMap projects offer?
The identification of all the genetic changes associated with a human cancer
Test your knowledge on the Human Genome Project and cancer genes, including KRAS, TP53, and APC. Learn about the systematic analysis of genetic alterations in tumors and the approaches used to discover cancer genes before elucidation of the human genome.
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