Human Embryonic Development and Reproductive Anatomy

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Questions and Answers

What is the primary purpose of capacitation in human fertilization?

  • To enable sperm to undergo cell division
  • To prepare the egg for fertilization
  • To allow sperm to fertilize the egg (correct)
  • To facilitate implantation in the uterus

At which stage is the embryo referred to as a blastula?

  • After cleavage and formation of morula (correct)
  • When the inner cell mass begins to differentiate
  • Upon implantation in the uterine wall
  • During fertilization

Which structure is responsible for forming the extraembryonic yolk sac during embryonic development?

  • Hypoblast (correct)
  • Syncytiotrophoblast
  • Cytotrophoblast
  • Epiblast

What significant process occurs during week 3 of human fetal development?

<p>Gastrulation leading to the formation of germ layers (A)</p> Signup and view all the answers

Which part of the blastocyst develops into the placenta?

<p>Trophoblast (A)</p> Signup and view all the answers

What is the primary function of the clitoris?

<p>Lubricating secretions for sexual arousal (A)</p> Signup and view all the answers

What are the labia minora primarily responsible for?

<p>Providing shock absorption and protection (B)</p> Signup and view all the answers

Which structure connects the ovaries to the uterus?

<p>Fallopian tube (C)</p> Signup and view all the answers

What role does the cervix play during childbirth?

<p>It dilates to permit the exit of the baby. (C)</p> Signup and view all the answers

What is the primary lining of the vagina composed of?

<p>Mucous membranes for moisture (C)</p> Signup and view all the answers

What is the primary function of the seminiferous tubules in the testes?

<p>Meiosis and sperm production (D)</p> Signup and view all the answers

Which of the following is NOT a function of the epididymis?

<p>Production of testosterone (D)</p> Signup and view all the answers

What does the seminal vesicle contribute to the semen?

<p>Alkaline, viscous fluid (C)</p> Signup and view all the answers

What happens to the endometrium if pregnancy does not occur?

<p>The endometrium sheds and causes bleeding (B)</p> Signup and view all the answers

Which hormone is primarily responsible for regulating menstruation bleeds?

<p>Progesterone (B)</p> Signup and view all the answers

What is the role of fructose in the seminal vesicle fluid?

<p>Provides energy for sperm (A)</p> Signup and view all the answers

What effect can low estrogen levels have on a woman’s health?

<p>It can lead to osteoporosis and irregular periods (B)</p> Signup and view all the answers

Which structure lies on the posterior bladder surface and is part of the spermatic cord?

<p>Vas deferens (D)</p> Signup and view all the answers

What is one of the primary components secreted by the seminal vesicle?

<p>Prostaglandins (D)</p> Signup and view all the answers

What symptom is NOT associated with fluctuating levels of progesterone?

<p>Improved sexual appetite (D)</p> Signup and view all the answers

Which gland is responsible for producing male gametes?

<p>Testes (C)</p> Signup and view all the answers

Which of the following is a potential effect of high estrogen levels?

<p>Uterine cancer (D)</p> Signup and view all the answers

What is the primary function of the scrotum?

<p>To regulate temperature and protect the testicles (A)</p> Signup and view all the answers

Which structure has a cup-shaped and coiled structure?

<p>Epididymis (A)</p> Signup and view all the answers

What is contained in the fluid produced by seminal vesicles that helps to coagulate semen?

<p>Vesiculase (C)</p> Signup and view all the answers

Which of the following components is NOT part of the male external reproductive structures?

<p>Seminiferous tubule (D)</p> Signup and view all the answers

What muscle is responsible for elevating the testes?

<p>Cremaster (C)</p> Signup and view all the answers

Which of the following accurately describes the glans of the penis?

<p>An expansion of the corpus spongiosum (B)</p> Signup and view all the answers

What does the term 'gonads' refer to?

<p>The primary sexual organs (B)</p> Signup and view all the answers

What is the main role of the erectile tissues in the penis?

<p>To provide structural support during erection (D)</p> Signup and view all the answers

How does the dartos muscle affect the scrotum?

<p>It wrinkles the scrotal skin (B)</p> Signup and view all the answers

Which germ layer is responsible for forming the nervous system and epidermis?

<p>Ectoderm (A)</p> Signup and view all the answers

What is the primary role of the mesoderm during development?

<p>Development of muscle tissue and blood (B)</p> Signup and view all the answers

Which extra-embryonic membrane is responsible for gas and nutrient exchange between the mother and embryo?

<p>Chorion (A)</p> Signup and view all the answers

Which structure develops into the placenta?

<p>Chorion (C)</p> Signup and view all the answers

During which stage of development does neurulation occur?

<p>Day 17 – Week 4 (A)</p> Signup and view all the answers

Which hormone is primarily produced by the placenta and is known as the pregnancy hormone?

<p>Human chorionic gonadotropin (hCG) (D)</p> Signup and view all the answers

What primary function is associated with the amniotic sac?

<p>Secretion of amniotic fluid (A)</p> Signup and view all the answers

Which hormone is responsible for uterine contractions during childbirth?

<p>Oxytocin (A)</p> Signup and view all the answers

Which of the following structures is part of the embryo's connection to the placenta?

<p>Umbilical cord (C)</p> Signup and view all the answers

What does the allantois develop into in mammals?

<p>Vascularized sac involved in gas exchange (C)</p> Signup and view all the answers

Which hormone is crucial for maintaining the uterine lining during pregnancy?

<p>Progesterone (A)</p> Signup and view all the answers

Which process describes the development of internal organs from the three germ layers?

<p>Organogenesis (C)</p> Signup and view all the answers

What is the primary function of human placental lactogen (hPL)?

<p>Promote fetal growth and provide nutrition (B)</p> Signup and view all the answers

What role does the yolk sac play during embryonic development?

<p>Nutrient storage and blood cell formation (C)</p> Signup and view all the answers

Flashcards

Capacitation of Sperm

The process where a sperm cell undergoes changes within the female reproductive tract to become capable of fertilizing an egg.

Cleavage

Rapid cell division of a fertilized egg, starting in the oviduct, ultimately forming a hollow ball of cells called the blastocyst.

Implantation

The process of the blastocyst attaching to the uterine wall, which marks the beginning of pregnancy.

Gastrulation

The formation of the three germ layers, endoderm, mesoderm, and ectoderm, from the bilaminar embryonic disc, leading to the development of various tissues and organs.

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Neurulation

The process of forming the nervous system from the ectoderm, starting with the neural tube, which further develops into the brain and spinal cord.

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Testes

The primary male sex organ responsible for producing sperm and testosterone.

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Seminiferous Tubules

Tiny, coiled tubes inside the testes where sperm cells are produced.

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Scrotum

A pouch of skin that holds the testes and helps regulate their temperature for optimal sperm production.

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Penis

The external organ involved in urination and the delivery of semen.

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Urethra

The tube that carries both urine and semen from the bladder and prostate gland to the outside.

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Glans

The part of the penis responsible for the release of semen.

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Prostate gland

A small gland that produces a fluid that contributes to semen.

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Bulbourethral glands

A pair of glands near the prostate that contribute to semen and are a source of pleasure during sex.

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Ectoderm

The outer layer of the three germ layers, it gives rise to the nervous system, epidermis, and neural crest-derived tissues.

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Mesoderm

The middle layer of the three germ layers, it gives rise to the notochord, axial skeleton, cartilage, connective tissue, trunk muscles, kidneys, and blood.

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Endoderm

The innermost layer of the three germ layers, it gives rise to the gastrointestinal, respiratory, urinary systems, and endocrine glands.

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Extra-embryonic Membranes

A set of membranes that envelop the fetus, located on the uterine endometrial layer.

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Chorion

The outermost membrane that surrounds the embryo, formed from layers of trophoblast and extra-embryonic mesoderm.

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Chorionic Villi

Finger-like extensions of the chorion that penetrate into uterine tissue to facilitate gas, blood, and waste exchange between the embryo and the mother.

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Amnion

The sac that completely surrounds the embryo and secretes amniotic fluid, formed from a combination of ectoderm and mesoderm.

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Allantois

A small vascularized sac originating from the yolk sac, it stores urinary waste and helps with nutrient and gas exchange.

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Yolk Sac

A small, membranous structure that helps form the umbilical blood vessels, produces nourishment, circulates gases, and generates cells for the umbilical cord, blood cells, and reproductive organs.

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Placenta

The vital link between maternal and embryonic systems, composed of fetal portion with chorionic villi and maternal portion with decidua basalis.

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Umbilical Cord

The connecting cord between the embryo and placenta, supplying oxygenated, nutrient-rich blood and returning deoxygenated, nutrient-depleted blood.

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Gestation

The period of pregnancy.

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Parturition

The process of childbirth.

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Lactation

A process involving hormonal changes that lead to the expulsion of milk from the breast.

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What are the testes?

Oval-shaped organs responsible for producing sperm cells and testosterone.

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What are the tunics that surround the testes?

These are the two protective layers surrounding the testes: the outer tunica vaginalis and the inner tunica albuginea, which extends inward as septa.

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What are the lobules in the testes?

These are wedge-shaped compartments within the testes, each containing highly coiled seminiferous tubules where meiosis occurs.

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What are the germinal epithelium and Sertoli cells?

The lining of the seminiferous tubules, composed of Sertoli cells that support and nourish developing sperm cells and germ cells that undergo meiosis to produce sperm.

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What is the seminiferous tubule?

A highly coiled tube within each lobule of the testes, responsible for the production of sperm cells through meiosis.

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What is the epididymis?

A comma-shaped organ attached to the posterior side of the testes, responsible for the storage, protection, and maturation of sperm cells.

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What is the vas deferens?

A muscular tube that transports mature sperm from the epididymis to the ejaculatory duct.

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What is the seminal vesicle?

This sac-like gland located behind the bladder contributes a significant amount of fluid to the semen, which includes fructose for energy, prostaglandins for uterine contractions, citric acid, and vesiculase.

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What is the clitoris?

The clitoris is a small, sensitive nub of flesh located at the top of the vulva, covered by a fold of skin called the prepuce. It contains sweat and oil-secreting glands, which produce lubricating secretions during sexual arousal and orgasm. The clitoris also plays a role in protecting the vulva from injury.

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What are the labia minora?

The labia minora are small, folds of skin located on either side of the vaginal opening. They help protect the vaginal opening, aid in urination, contribute to sexual function, absorb shock, and provide cushioning during intercourse.

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What is the vagina?

The vagina is a muscular canal lined with mucous membranes, which secrete fluids that keep the vagina moist. It plays a crucial role in sexual intercourse, menstrual flow, and childbirth.

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What is the cervix?

The cervix is the lower part of the uterus. It connects the uterus to the vagina. It allows sperm to enter the uterus, menstrual blood to exit, and expands during childbirth.

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What are the fallopian tubes?

The fallopian tubes are two tubes that connect the ovaries to the uterus. They provide a passageway for the egg to travel from the ovary to the uterus and are the site of fertilization. The fallopian tubes have finger-like structures called fimbriae that catch the egg after its release from the ovary.

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What happens if pregnancy doesn't occur?

This is the stage in the menstrual cycle where the lining of the uterus (endometrium) sheds resulting in bleeding. It occurs when the corpus luteum, a temporary structure in the ovary, degenerates and stops producing progesterone, a hormone essential for maintaining the uterine lining.

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What is the corpus luteum?

A yellowish body that forms in the ovary after an egg is released. It produces progesterone, which helps prepare the uterus for a potential pregnancy.

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What is the role of Progesterone?

A hormone primarily produced by the corpus luteum in the ovary. It plays a major role in preparing the uterus for pregnancy, helps regulate menstruation, and thickens cervical mucus to prevent infection.

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What is the endometrium?

The inner lining of the uterus. It thickens and becomes ready for implantation of a fertilized egg. During menstruation, the endometrium is shed if pregnancy does not occur.

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What is Estrogen?

The primary female sex hormone produced by the ovaries. It plays a vital role in regulating the menstrual cycle, supporting female reproductive health, and influencing various bodily functions.

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Study Notes

Human Fetal Development

  • Human fetal development encompasses various stages, from fertilization to birth
  • Key stages include fertilization, cleavage stage, implantation, gastrulation, organogenesis, and neurulation.
  • The development is a complex process involving several stages.

Capacitation & Fertilization

  • Capacitation is the change sperm undergoes in the female reproductive tract.
  • Fertilization is the fusion of the sperm and ovum to initiate embryonic development.

Cleavage & Implantation

  • Cleavage stage involves rapid cell division in the oviduct
  • Day 3-4: Morula formation.
  • Day 6-7: Blastocyst forms, with trophoblast and embryoblast.
  • The blastocyst burrows into the implantation site on the uterine wall.
  • Trophoblast differentiates into cytotrophoblast and syncytiotrophoblast.
  • Embryoblast differentiates into hypoblast and epiblast.

Gastrulation

  • Gastrulation refers to a migration of blastocyst inward.
  • It leads to multiple distinct tissue layers called germ layers.
  • Gastrulation in week 3 leads to a trilaminar structure, the gastrula.
  • The epiblast cells migrate towards the primitive streak, becoming flask-shaped, detach and slip beneath.
  • This process results in the formation of ectoderm, mesoderm, and endoderm layers.

Organogenesis

  • Organogenesis(week 3-8) is a process involving three germ layers, which develop into the internal organs and tissues of the organism.
  • Neurulation (day 17- week 4) is the formation of the neural tube, forming the central nervous system.

Extra-embryonic Membranes

  • Extra-embryonic membranes (amnion, yolk sac, allantois, chorion, and placenta) support and protect the developing embryo.
  • Amnion completely surrounds the embryo and secrets amniotic fluid.
  • Yolk sac is a small, membranous structure that helps in nourishment and gas circulation, and develops into reproductive organs.
  • Allantois originates from the yolk sac.
  • Chorion, the outermost membrane, surrounds the embryo.
  • It develops into the placenta, allowing for nutrient and gas exchange between the embryo and mother.

Placenta

  • The placenta is a vital link between the maternal and embryonic systems.
  • It allows gas, blood, and waste exchange between the embryo and mother's circulatory system.
  • The fetal portion includes chorionic villi, while the maternal portion comprises the decidua basalis.

Umbilical Cord

  • The umbilical cord connects the embryo to the placenta.
  • It supplies oxygenated, nutrient-rich blood to the embryo and returns deoxygenated, nutrient-depleted blood to the placenta.
  • It contains arteries and a vein.

Gestation

  • The period of pregnancy is divided into three trimesters: 1st, 2nd, and 3rd.
  • Hormonal changes during pregnancy—especially those affecting the uterine lining, and preparing for childbirth.

Hormones Involved in Gestation, Parturition, and Lactation

  • Hormones like hCG, progesterone, and estrogen are crucial during gestation.
  • Oxytocin is involved in uterine contractions during childbirth, and in milk letdown during lactation.
  • Human placental lactogen (hPL) supports fetal nutrition.

Parturition (Childbirth)

  • Parturition is the process of childbirth, characterized by hormone-stimulated contractions.
  • Stages of Labour
  • There are various hormones involved in the process.

Positive Feedback Mechanisms During Parturition

  • The positive feedback mechanisms are crucial in childbirth.
  • During labour, the fetal hypothalamus releases hormones, which lead to the release of further hormones, strengthening the contractions and leading to childbirth.

Lactation

  • Lactation refers to milk production in the mother's breasts after childbirth.
  • Oxytocin stimulates milk letdown.
  • Prolactin stimulates milk production.

Male Reproductive System

  • Gametes (sperm) are produced in the testes.
  • The gonads include the testes and ovaries.
  • The male reproductive system has associated ducts and glands.
  • Structures include the testes, epididymis, vas deferens, seminal vesicles, prostate gland, and bulbourethral glands.

Female Reproductive System

  • Gametes (ova) are produced in the ovaries.
  • Structures include the ovaries, fallopian tubes, uterus, cervix, and vagina.

Reproductive Issues in Men & Women

  • Various reproductive issues can affect men and women, including structural, hormonal, and genetic disorders.

Spermatogenesis

  • Spermatogenesis is the process of sperm production in males.
  • This involves several stages, from germ cell divisions to maturation, culminating in the spermatozoa.
  • Hormonal factors such as FSH and LH are crucial in spermogenesis.

Oogenesis

  • Oogenesis is the process of ovum (egg) production in females.
  • Oogenesis involves multiplication, growth, and maturation in stages, to form the egg.
  • Hormonal factors, like FSH and LH stimulate the process.

Menstrual Cycle

  • The menstrual cycle involves the cyclical changes in the uterine lining in preparation for potential fertilization.
  • Stages in the menstrual cycle include follicular phase, ovulation phase, and luteal phase.

Roles of Hormones

  • Hormones like estrogen and progesterone play crucial roles in the reproductive system.
  • Their levels fluctuate throughout the menstrual cycle, impacting the uterine lining and ovulation in females.

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