Podcast
Questions and Answers
What primarily happens during the process of implantation?
Where does implantation typically occur within the uterus?
Which power of the trophoblast helps in implanting the blastocyst into the endometrium?
What defines placenta previa centralis?
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What is the most common type of ectopic pregnancy?
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What is the primary hormone influencing the structure of the decidua during pregnancy?
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Which part of the decidua forms the maternal aspect of the placenta?
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What is the fate of the decidua capsularis during pregnancy?
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The inner cell mass of the blastocyst differentiates into what structure?
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What do the somatic and splanchnic mesoderms surround in the blastocyst formation?
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What type of trophoblast layer produces human chorionic gonadotropin (HCG)?
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What structure is formed between the epiblast and amnioblast?
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Which combination of layers form the chorion?
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What primarily causes the loss of the zona pellucida during implantation?
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Which form of placenta previa involves the placenta completely covering the internal os?
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What is a potential complication of a tubal ectopic pregnancy?
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In which anatomical location does implantation of the blastocyst typically occur?
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What is the histolytic power of the trophoblast responsible for during implantation?
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What is the primary hormonal influence on the decidua during pregnancy?
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What structural change occurs to the decidua parietalis during pregnancy?
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Which part of the inner cell mass gives rise to the upper columnar layer?
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What significant function does the syncytiotrophoblast perform during implantation?
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What is formed by the somatic mesoderm during early development?
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Which of the following describes the fate of the decidua basalis?
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What structures are encompassed by the term 'chorion'?
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Which layer of the trophoblast is responsible for eroding the endometrium?
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Study Notes
Second Week Implantation
- Definition: Embedding the blastocyst into the endometrium
- Site: Upper posterior uterine wall, near the fundus
- Time: Begins at the end of the first week and continues until the end of the second week
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Mechanism:
- Loss of zona pellucida exposes the trophoblast
- Exposed trophoblast has two abilities:
- Adhesive power: Attaches to the endometrium
- Histolytic power (enzymatic): Enables the blastocyst to digest the endometrium
- Fibrin plug fills the digested area
Anomalies of Implantation
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Placenta Previa: Implantation of the blastocyst into the lower uterine segment
- Lateralis: Placenta is away from the internal os
- Marginalis: Placenta partially covers the internal os
- Centrals: Placenta completely covers the internal os
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Ectopic Pregnancy: Implantation of the blastocyst outside the uterine cavity
- Tubal (most common): Caused by early loss of zona pellucida or delayed transport of zygote
- Ovarian: Primary is implantation into the ovary; secondary is rupture of a tubal pregnancy
- Peritoneal (abdominal): Primarily in the recto-uterine pouch
Decidua
- Definition: Endometrium of a pregnant uterus
- Structure: Similar to the endometrium in the secretory phase
- Hormonal control: Under the influence of progesterone
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Parts:
- Decidua capsularis: Part of the endometrium covering the fetus; Fuses and degenerates
- Decidua parietalis: Part of the endometrium lining the uterine cavity; Fuses and degenerates
- Decidua basalis: Part of the endometrium between the fetus and myometrium; Forms the maternal part of the placenta
Blastocyst Changes ("Chorionic Vesicle Formation")
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Trophoblast: Outer layer of trophoblast
- Syncytiotrophoblast: Produces proteolytic enzymes to erode the endometrium; secretes human chorionic gonadotropin (hCG) to maintain corpus luteum and progesterone production for 4 months.
- Cytotrophoblast: Inner layer of trophoblast
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Inner cell mass: Becomes a bilaminar disc
- Epiblast: Upper layer
- Hypoblast: Lower layer
- Blastocele: Becomes the amniotic cavity between epiblast and amnioblast, and primary yolk sac between hypoblast and Hausser membrane
- Extraembryonic mesoderm: Divides & forms somatic and splanchnic mesoderm. Somatic lines cytotrophoblast, splanchnic covers yolk sac. They remain in contact, forming the connecting stalk (umbilical cord).
- Chorion: Formed by syncytiotrophoblast, cytotrophoblast and somatic extraembryonic mesoderm
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