Human Biology: Blood and Immune System Quiz

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Questions and Answers

What is the primary role of neutrophils in the immune system?

  • Producing antibodies
  • Forming platelet plugs
  • Phagocytosing bacteria (correct)
  • Regulating blood volume

Which type of white blood cell transforms into macrophages?

  • Neutrophils (correct)
  • Basophils
  • Eosinophils
  • Granulocytes

What is the lifespan of platelets (thrombocytes) in the bloodstream?

  • 5-7 days
  • 7-8 days (correct)
  • 1-3 days
  • 10-12 days

What structural feature is characteristic of a neutrophil's nucleus?

<p>Multilobulated structure (C)</p> Signup and view all the answers

What distinguishes platelets from typical blood cells?

<p>Cellular fragments without a nucleus (C)</p> Signup and view all the answers

What is the function of albumin in the blood plasma?

<p>Helps retain water due to osmotic pressure (C)</p> Signup and view all the answers

Which component of red blood cells primarily binds to oxygen in the lungs?

<p>Hemoglobin (B)</p> Signup and view all the answers

What initiates the process of erythropoiesis?

<p>Decrease in oxygen levels (hypoxia) (B)</p> Signup and view all the answers

In what locations does the production of red blood cells (erythropoiesis) primarily occur?

<p>Red bone marrow of several bones (D)</p> Signup and view all the answers

What is the primary solvent in blood plasma?

<p>Water (A)</p> Signup and view all the answers

How does hemoglobin release oxygen once it reaches the body's tissue capillaries?

<p>First into interstitial fluid and then to cells (A)</p> Signup and view all the answers

What happens to carbon dioxide when blood flows to the lungs?

<p>It is released from hemoglobin and exhaled (D)</p> Signup and view all the answers

Which type of plasma protein is primarily responsible for immune function?

<p>Globulins (A)</p> Signup and view all the answers

What is the primary effect of prolactin (PRL) after childbirth?

<p>Stimulates and maintains milk production (C)</p> Signup and view all the answers

Which hormone regulates the cortical portion of the adrenal gland?

<p>Adrenocorticotropic hormone (A)</p> Signup and view all the answers

What network connects the blood supply of the hypothalamus and the anterior pituitary gland?

<p>Hypophyseal portal circulation (A)</p> Signup and view all the answers

Which type of gonadotropic hormone stimulates follicle development in ovaries?

<p>Follicle stimulating hormone (B)</p> Signup and view all the answers

What characterizes acromegaly?

<p>Enlargement of bones in the face (A)</p> Signup and view all the answers

The secondary plexus is formed by which type of blood vessels?

<p>Hypophyseal portal veins (D)</p> Signup and view all the answers

What role does the hypothalamus play in regulating the anterior pituitary gland?

<p>Controls the secretion of releasing and inhibiting hormones (D)</p> Signup and view all the answers

What is the primary function of heparin released from certain leukocytes?

<p>Act as an anticoagulant (D)</p> Signup and view all the answers

Which arteries contribute to the superior hypophyseal arteries?

<p>Branch of the internal carotid and anterior communicating arteries (B)</p> Signup and view all the answers

What type of nucleus do agranular leukocytes exhibit?

<p>Unsegmented nucleus (C)</p> Signup and view all the answers

What is the result when type A blood from a donor is mixed with a recipient who has anti-B antibodies?

<p>No reaction occurs (A)</p> Signup and view all the answers

What happens if an RH negative individual receives RH positive blood?

<p>The individual will develop RH antibodies (A)</p> Signup and view all the answers

Which of the following statements about the coagulation process is accurate?

<p>Vasoconstriction occurs for only about 20 minutes (C)</p> Signup and view all the answers

What is the importance of the D antigen in the context of blood type?

<p>It is significant in antibody production (B)</p> Signup and view all the answers

Which substance released by leukocytes constricts vascular smooth muscles?

<p>Serotonin (B)</p> Signup and view all the answers

What condition can arise from an RH negative individual receiving RH positive transfusions?

<p>Erythroblastosis fetalis (D)</p> Signup and view all the answers

Which of the following glands are classified as small salivary glands?

<p>Palatine (C)</p> Signup and view all the answers

What are the two major lobes of the liver?

<p>Left and Right (C)</p> Signup and view all the answers

What is the length of the small intestine?

<p>5 meters (C)</p> Signup and view all the answers

Which of the following segments is NOT part of the small intestine?

<p>Caudate (D)</p> Signup and view all the answers

What is stored in the gallbladder?

<p>Bile (D)</p> Signup and view all the answers

Which portion of the small intestine is primarily retroperitoneal?

<p>Duodenum (C)</p> Signup and view all the answers

Which type of hepatic cells primarily make up the liver?

<p>Hepatocytes (A)</p> Signup and view all the answers

What is the primary function of the small intestine?

<p>Digestion and food absorption (D)</p> Signup and view all the answers

What is the function of the right lymphatic duct?

<p>Drains lymph from the right side of the head and neck (A)</p> Signup and view all the answers

What is the primary function of suppressor T-cells?

<p>Terminate normal immune responses (B)</p> Signup and view all the answers

Where do B-cells develop before entering the circulatory and lymph systems?

<p>Bone marrow (A)</p> Signup and view all the answers

What is the primary immune response characterized by?

<p>Clonal selection and differentiation of B-cells (B)</p> Signup and view all the answers

What role do macrophages in lymph nodes play?

<p>Engulf and destroy bacteria and cancer cells (B)</p> Signup and view all the answers

Flashcards

Plasma

The liquid portion of blood, primarily composed of water, plasma proteins, electrolytes, nutrients, waste products, and gases.

Hemoglobin

A globular protein found in red blood cells that binds and carries oxygen throughout the body.

Erythropoiesis

The process by which red blood cells are produced, primarily in the red bone marrow.

Erythropoietin (EPO)

A hormone produced by the kidneys that stimulates the production of red blood cells.

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Macrophages

The specialized cells that engulf and remove old or damaged red blood cells from the body, primarily in the spleen.

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Acid-Base Balance

The ability of the blood to maintain a stable pH level, primarily due to the presence of buffers.

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Albumin

A type of plasma protein that helps to control the osmotic pressure of blood, maintaining fluid balance.

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Gas Diffusion

The process of gas exchange between the blood and tissues, where oxygen is delivered and carbon dioxide is removed.

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Neutrophil

A type of white blood cell (WBC) that is characterized by its ability to engulf and destroy bacteria and other foreign substances.

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Leukopoiesis

The production of white blood cells (WBCs), involving a series of stages within the bone marrow.

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Thrombopoiesis

The process of platelet formation, starting from megakaryocytes in the bone marrow.

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Eosinophil

A type of white blood cell (WBC) that plays a key role in allergic responses, parasitic infections, and inflammation.

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Basophil

A type of white blood cell (WBC) that releases chemicals like histamine, contributing to allergic and inflammatory reactions.

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Lymphatic Vessels

A series of vessels that transport lymph fluid throughout the body, collecting excess fluid and returning it to the bloodstream.

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Cisterna Chyli

An enlarged sac at the base of the thoracic duct that collects lymph from the lower limbs and digestive organs.

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B cells

White blood cells that differentiate in the bone marrow and provide humoral immunity through the production of antibodies.

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T cells

White blood cells that are involved in cell mediated immunity, directly attacking infected or cancerous cells.

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Primary Immune Response

The initial immune response to a specific antigen, involving clonal selection and differentiation of B cells, leading to antibody production.

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S-shaped nucleus

A type of white blood cell with a distinctive S-shaped nucleus. It releases heparin, an anticoagulant, and SRS-A, a substance involved in allergic reactions.

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Agranular Leukocyte

A category of white blood cells that lack granules in their cytoplasm. They include lymphocytes and monocytes.

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Lymphocyte

A type of agranular leukocyte responsible for adaptive immunity. They produce antibodies and target specific pathogens.

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Monocyte

A type of agranular leukocyte that transforms into macrophages, which engulf and destroy foreign substances.

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Rh system

A blood group system based on the presence or absence of the Rh antigen on red blood cells. It's important for blood transfusions and preventing hemolytic disease in newborns.

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D Antigen

The most important antigen in the Rh system. When present, individuals are Rh positive, and when absent, they are Rh negative.

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Hemolytic disease of the newborn

A condition where the immune system of an Rh-negative mother attacks the red blood cells of an Rh-positive fetus, leading to potential complications.

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Agglutination Reaction

A reaction where antibodies in the recipient's blood combine with antigens on donor red blood cells, causing agglutination (clumping) and potentially, hemolysis (destruction of red blood cells).

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What is acromegaly?

A condition caused by excessive growth hormone production after the growth plates have fused, resulting in bone enlargement, particularly in the face.

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How is the pituitary gland regulated?

The pituitary gland is controlled by the hypothalamus through hormones called "releasing" and "inhibiting" hormones, which are transported through the portal circulation.

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What is the portal circulation?

A network of blood vessels that links the hypothalamus to the anterior pituitary gland, allowing for the transportation of hormones.

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What is prolactin?

The hormone responsible for stimulating and maintaining milk production in lactating women.

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What is adrenocorticotropic hormone (ACTH)?

A hormone produced by the pituitary gland that regulates the adrenal cortex, which is responsible for producing stress hormones.

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What is thyroid stimulating hormone (TSH)?

A hormone also known as thyrotropic hormone, secreted by the pituitary gland, that regulates the growth and activity of the thyroid gland.

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What are gonadotropic hormones?

Hormones that regulate the hormonal activity of the gonads (ovaries and testes).

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What is follicle-stimulating hormone (FSH) in females?

A gonadotropic hormone that stimulates follicle development in the ovaries, leading to estrogen production and preparation for ovulation.

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Duodenum

The first part of the small intestine, where most digestion occurs; it receives bile from the gallbladder and pancreatic juices from the pancreas.

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Jejunum

The middle part of the small intestine, where most nutrient absorption takes place.

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Ileum

The last part of the small intestine, responsible for absorbing remaining nutrients and water.

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Gallbladder

A pear-shaped sac located beneath the liver that stores and concentrates bile.

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Bile

A fluid produced by the liver, stored in the gallbladder, and released into the small intestine to help break down fats.

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Pancreas

A large gland that produces digestive enzymes (like lipase) and hormones (like insulin).

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Liver

The largest internal organ in the body, located in the upper right abdomen. It plays multiple roles in digestion, detoxification, and storage.

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Hepatocytes

Cells in the liver responsible for most of its functions.

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Study Notes

Blood

  • Liquid connective tissue, part of the cardiovascular system
  • Maintains homeostasis
  • Makes up 7-9% of an adult's body weight
  • Male average: 5-6 liters
  • Female average: 4-5 liters
  • Red color of arterial blood due to oxygenated hemoglobin (Hgb)
  • Functions: transport, protection, regulation

Blood Functions

  • Transport: oxygen from the lungs to body tissues
  • Protection: blood clotting prevents excessive blood loss during injury; host defences via antibody production; platelets maintain hemostasis; regulates pH (acid-base balance); albumin maintains blood volume and pressure, regulates heat dissipation by varying blood flow.
  • Regulation: acid-base balance; osmotic pressure; heat regulation

Plasma

  • Liquid portion of blood

  • Composition: water (90%), plasma proteins (albumin, globulins, fibrinogen), plasma electrolytes, nutrients, waste products, gasses, and buffers

  • Water: Solvent for nutrient transport

  • Plasma Proteins: (mostly from the liver)

    • Albumin: water retention, blood volume, pressure
    • Globulins: transport fat-soluble vitamins (ADEK), antibodies
    • Fibrinogen: blood clotting
  • Plasma Electrolytes: inorganic molecules (ions), e.g., sodium, potassium, calcium, chloride

  • Nutrients: glucose, amino acids, lipids

  • Waste Products: lactic acid, urea

  • Gasses: oxygen, nitrogen, carbon dioxide

  • Buffers: maintain pH

Formed Elements

  • Whole cells and cell fragments
  • Red Blood Cells (RBCs) / Erythrocytes:
    • Average: Male = 5.5 million/cu.mm; Female = 4.8 million/cu.mm
    • Size: 7 μm
    • Biconcave disc shape for gas diffusion
    • Anucleated, no nucleus
    • Contains hemoglobin (Hgb) for oxygen transport
    • Life span: 120 days
    • Removed by macrophages in spleen
  • White Blood Cells (WBCs) / Leukocytes:
    • 5,000-10,000 cells/mm³
    • Have nuclei
    • Do not contain hemoglobin
    • Combat pathogens by phagocytosis and immune response
    • Types: Granular (neutrophils, eosinophils, basophils), Agranular (lymphocytes, monocytes)
  • Platelets (Thrombocytes):
    • 150,000-400,000 cells/mm³
    • Cell fragments, no nucleus
    • Life span: 7-8 days
    • Involved in blood clotting

Erythropoiesis

  • Production of red blood cells
  • Stimulated by hypoxia (low oxygen) via erythropoietin (EPO) hormone from kidneys

Blood Disorders

  • Anemia: Reduced oxygen-carrying capacity
  • Hemophilia: Inherited clotting deficiency

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