Human Anatomy Circulatory System Quiz
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Questions and Answers

What is the primary mechanism driving intermittent blood flow within capillary beds?

  • Arteriolar innervation
  • Venous pulsation
  • Lymphatic drainage
  • Vasomotion (correct)
  • How does decreased oxygen concentration impact precapillary sphincters?

  • It has no impact on the state of the sphincters.
  • It causes the sphincters to relax, increasing blood flow into the capillaries. (correct)
  • It causes the sphincters to contract, reducing blood flow into the capillaries.
  • It causes the blood to flow away from the capillaries.
  • How much of the blood volume is typically composed of solids?

  • Approximately 30%
  • Approximately 8% (correct)
  • Approximately 2%
  • Approximately 92%
  • Where do most cells obtain their nutrient and oxygen requirements?

    <p>Via the interstitial fluid (A)</p> Signup and view all the answers

    Which of these is NOT a characteristic of metarterioles and precapillary sphincters?

    <p>They are innervated by the autonomic nervous system (C)</p> Signup and view all the answers

    Which layer of a blood vessel wall contains the endothelium?

    <p>Tunica Intima (C)</p> Signup and view all the answers

    What is the primary component of the tunica media in a large artery like the aorta?

    <p>Elastic tissue (D)</p> Signup and view all the answers

    Which of the following best describes the tunica adventitia?

    <p>Connective tissue mainly made of collagen fibers with very little elastic component (A)</p> Signup and view all the answers

    Which vessels are more likely to have vasa vasorum?

    <p>Large arteries (B)</p> Signup and view all the answers

    What structural feature is characteristic of veins but not typically found in arteries?

    <p>Valves (B)</p> Signup and view all the answers

    What best describes the difference between elastic and muscular arteries?

    <p>Elastic arteries have a larger component of elastin in the tunica media (C)</p> Signup and view all the answers

    Which of the following is true about the walls of arteries and veins?

    <p>The walls of arteries are more distinct compared to veins (B)</p> Signup and view all the answers

    What is a notable characteristic of veins, compared to arteries, concerning their lumen and wall thickness?

    <p>Veins typically have a thinner wall and a larger lumen in relation to the size of the vessel (B)</p> Signup and view all the answers

    Which of the following plasma proteins has the highest concentration in human blood?

    <p>Albumin (B)</p> Signup and view all the answers

    What is the approximate maximum distance of a cell from a capillary?

    <p>20-30 μm (B)</p> Signup and view all the answers

    What is the primary force that pushes fluid out of the arterial capillaries?

    <p>Capillary hydrostatic pressure (D)</p> Signup and view all the answers

    What is the main cause of fluid absorption back into the capillaries, according to the text?

    <p>Plasma colloid osmotic pressure (C)</p> Signup and view all the answers

    What is the main function of preferential channels or arterio-venous anastomoses?

    <p>To directly shunt blood from the arterial to the venous side (D)</p> Signup and view all the answers

    Which of the following is NOT a fluid exchange pressure?

    <p>Blood viscosity (B)</p> Signup and view all the answers

    What is a distinguishing feature of non-fenestrated capillaries?

    <p>They exhibit low permeability (D)</p> Signup and view all the answers

    What is the approximate total amount of solids as a percentage of blood, according to the text?

    <p>8.3% (B)</p> Signup and view all the answers

    What type of capillary is most likely to be found in the kidney based on its description?

    <p>Fenestrated (A)</p> Signup and view all the answers

    Which of these best describes the nature of interstitial fluid pressure in fluid exchange?

    <p>A negative pressure that pulls fluid out of the capillary (A)</p> Signup and view all the answers

    Which statement accurately describes the characteristic of discontinuous capillaries?

    <p>They have large gaps between lining cells and high permeability, as well as lacking a basement membrane. (B)</p> Signup and view all the answers

    What structural feature helps red blood cells pass through non-fenestrated capillaries?

    <p>The flexibility of the red blood cell (D)</p> Signup and view all the answers

    How many pressures are directly pushing fluid out of the capillary, according to the text?

    <p>3 (C)</p> Signup and view all the answers

    Which of the following values is the closest to the plasma colloid osmotic pressure?

    <p>28 mmHg (A)</p> Signup and view all the answers

    What is a typical diameter of a discontinuous capillary?

    <p>30-40 μm (D)</p> Signup and view all the answers

    Which of the following features is common to all types of capillaries?

    <p>A layer of one or two endothelial cells (D)</p> Signup and view all the answers

    What is the net outflow of fluid at the arterial end of a capillary, as calculated from the provided data?

    <p>+8.3 mmHg (B)</p> Signup and view all the answers

    What is the primary reason for the negative value associated with interstitial fluid pressure?

    <p>It creates a force that draws fluid into the tissue. (B)</p> Signup and view all the answers

    Which force predominantly draws fluid back into the capillaries at the venous end?

    <p>Plasma colloid osmotic pressure. (A)</p> Signup and view all the answers

    According to the information, what is the estimated net body filtration rate per day?

    <p>2.5 - 5.0 liters (D)</p> Signup and view all the answers

    In which direction does diffusion occur across the entire body capillary network?

    <p>In both directions (B)</p> Signup and view all the answers

    What happens to the portion of fluid which is not reabsorbed into the venous capillaries?

    <p>It is transported to the lymphatic system. (B)</p> Signup and view all the answers

    What is the net fluid movement at the venous end of the capillary?

    <p>Fluid movement into the capillary (C)</p> Signup and view all the answers

    What is the rate of diffusion throughout the entire body capillary network?

    <p>240 litres/per minute (A)</p> Signup and view all the answers

    What is the primary function of the lymphatic system in relation to interstitial fluid?

    <p>To collect excess fluid and return it to the circulation (B)</p> Signup and view all the answers

    Where does the fluid that is eventually processed by the lymphatic system originate?

    <p>From the interstitial tissue (D)</p> Signup and view all the answers

    Why is it important that the lymphatic system monitors the fluid returning to the blood?

    <p>To detect and filter out pathogens or inflammatory agents (B)</p> Signup and view all the answers

    What structure initially collects the interstitial fluid for the lymphatic system?

    <p>Blind-starting lymphatic capillaries (C)</p> Signup and view all the answers

    Which of the following is NOT a key process performed by the lymphatic system as described in the text?

    <p>Directly oxygenating tissues (A)</p> Signup and view all the answers

    Flashcards

    Tunica Intima

    The innermost layer of blood vessels. It's made up of endothelium and connective tissue containing elastic fibers and collagen fibers.

    Tunica Media

    The middle layer of blood vessels, composed of smooth muscle, collagen fibers, and elastic fibers. It's responsible for controlling blood pressure and flow.

    Tunica Adventitia/Externa

    The outermost layer of blood vessels, composed of connective tissue with collagen fibers. It provides structural support and anchors the vessel to surrounding tissues.

    Elastic Arteries

    Large arteries, like the aorta, with a thick tunica media rich in elastic fibers. They are able to stretch and recoil to accommodate changes in blood pressure.

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    Muscular Arteries

    Smaller arteries with a thicker tunica media containing more muscle fibers than elastic fibers. They play a significant role in regulating blood flow to specific organs.

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    Vasa Vasorum

    Tiny blood vessels that branch off the aorta and other major arteries, responsible for supplying nutrients and oxygen to the walls of larger vessels.

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    Shape of Arteries and Veins

    Difference in blood vessel shape. Arteries tend to be round or oval due to the pressure of blood pushing outwards, whereas veins are often more irregular.

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    Thin walls and wider lumen

    Feature of veins - thin walls, larger lumen. Veins have a larger inner space and a thinner wall compared to arteries, making them more flexible, allowing blood to flow back to the heart.

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    Sinusoidal capillary

    A type of capillary that allows for the passage of blood cells, characterized by large gaps between endothelial cells.

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    Vasomotion

    The intermittent flow of blood in the capillary beds, regulated by the contraction and relaxation of smooth muscles in the metarterioles and precapillary sphincters.

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    Preferential channel

    A specialized channel in capillaries that facilitates the rapid transport of fluids and small molecules, bypassing the usual capillary walls.

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    Plasma

    The fluid portion of blood, composed primarily of water and containing dissolved substances such as proteins, electrolytes, and nutrients.

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    Oxygen autoregulation

    A process that automatically adjusts blood flow based on the oxygen levels in tissues. Increased oxygen levels cause smooth muscle contraction, closing off precapillary sphincters and directing blood flow through metarterioles; decreased oxygen levels lead to smooth muscle relaxation, opening precapillary sphincters and allowing blood flow through the capillaries.

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    Capillary beds

    Tiny blood vessels that form a network throughout the body, connecting arteries and veins.

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    Capillaries

    The smallest blood vessels in the body, allowing for exchange of substances between blood and tissues.

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    Non-fenestrated capillaries

    Capillaries that have a continuous lining with no gaps or pores, making them less permeable to substances.

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    Fenestrated capillaries

    Capillaries that have small 'windows' or pores in their lining, making them more permeable than non-fenestrated capillaries.

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    Discontinuous capillaries

    Capillaries that have large gaps between their lining cells, making them highly permeable to substances and even allowing blood cells to pass through.

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    Arteriovenous anastomoses (AVAs)

    Direct pathways that connect arteries and veins, bypassing capillary beds and allowing for quick blood passage.

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    Pericytes

    Cells that help regulate blood flow through capillaries by constricting or relaxing.

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    Endothelial cells

    The lining of capillaries that is composed of a single layer of endothelial cells.

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    Capillary Hydrostatic Pressure

    The force exerted by the blood inside the capillary, pushing fluid out.

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    Plasma Colloid Osmotic Pressure

    The force exerted by plasma proteins, pulling fluid back into the capillary.

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    Interstitial Fluid Pressure

    The pressure created by interstitial fluid, pushing fluid out of the capillary.

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    Interstitial Fluid Colloid Osmotic Pressure

    The force exerted by proteins in the interstitial fluid, pulling fluid out of the capillary.

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    Filtration

    The movement of fluid from an area of high pressure to low pressure, through a membrane.

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    Diffusion

    The movement of molecules from an area of high concentration to low concentration.

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    Net Filtration Rate

    The net movement of fluid out of the capillaries, due to the difference in pressures.

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    Lymphatic System

    The system in the body that collects excess fluid and returns it to the bloodstream.

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    Fluid exchange

    The process of fluid moving into and out of capillaries, driven by differences in pressure and osmotic forces.

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    Plasma Proteins

    The collection of proteins found in the plasma, primarily albumin, globulins, and fibrinogen.

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    Albumin

    The main protein in plasma, responsible for maintaining blood volume and osmotic pressure.

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    Globulins

    A group of proteins in plasma with various functions, including immunity and transport.

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    Interstitial Fluid

    The fluid that remains in the spaces between cells after exchange processes in the capillaries occur. It contains nutrients, oxygen, and waste products. This fluid needs to be returned to the circulatory system.

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    Lymphatic Capillaries

    Tiny, blind-ended vessels found in the tissues. They collect excess interstitial fluid, which is the fluid that remains in the spaces between cells. This fluid then flows through the lymphatic vessels, eventually returning to the circulatory system.

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    Lymph Nodes

    Enlarged lymph nodes function as filters in the lymphatic system. They are filled with immune cells that monitor the fluid for potential threats. These cells help fight infections and diseases.

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    Lymphatic System's Importance

    The lymphatic system acts as monitoring system for the circulatory system. As it collects fluid from the tissues, it also removes waste products, pathogens, and cellular debris. These substances are then filtered by the lymph nodes, where immune cells identify and destroy harmful organisms.

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    Study Notes

    Cardiovascular System, Biological Fluids, Renal Function

    • The systematic circulation, blood vessels, and capillary networks are discussed.

    Learning Outcomes

    • Students will be able to discuss different types of circulatory systems (open and closed).
    • Students will be able to describe the function and histology of blood vessels (arteries, veins, and capillaries).
    • Students will be able to describe and explain fluid exchange dynamics in capillary beds.

    Circulatory Systems

    • Open systems: The heart pumps blood directly to tissues within arteries; no venous return (e.g., arthropods).
    • Closed systems: Blood remains within vessels; this system includes all intercommunicating fluid systems of the body.
    • There are five fluid systems within the body: Blood vascular system, Lymphatic system, Cerebrospinal fluid, Coelomic/peritoneal fluid, and Interstitial fluid.

    Blood Vascular System

    • The primary function of the blood system is transporting materials necessary for metabolism and synthesis, and transporting waste products.
    • Oxygen and nutrients are delivered to cells, and carbon dioxide and nitrogenous wastes are removed.
    • Blood vessels are dynamic and adaptable to tissue needs; the three layers are the tunica intima, tunica media, and tunica adventitia/externa.
    • Arteries, capillaries, and veins are part of a continuous system with smooth transitions between them.

    Blood Vessels - Histology

    • Blood vessels continually adapt to tissue needs.
    • Arteries and veins have three layers: tunica intima, tunica media, and tunica adventitia/externa.
    • Arteries:
      • Endothelium and connective tissue with elastic and collagen fibers
      • Larger elastic components in the aorta; smaller muscular arteries have smooth muscle
    • Veins:
      • Endothelium and smooth muscle
      • Collagen fibers are thicker in veins than arteries
    • Blood vessels have a vasa vasorum (vessels supplying the blood vessels) in larger vessels, and valves in veins.

    Capillaries

    • Capillaries (8-12 µm) are single endothelial cell layers.
    • Blood volume in capillaries is typically 5% total.
    • Blood flows through capillary beds intermittently thanks to precapillary sphincters.
    • Three types of capillaries: Non-fenestrated (small pores, low permeability), Fenestrated (large pores, high permeability), Discontinuous (largest pores, high permeability).
    • Cells obtain nutrients and oxygen from interstitial fluid.

    Physiology - Capillary Dynamics

    • Few cells come in direct contact with capillaries
    • Blood exchanges materials with interstitial cells.
    • Blood volume generally around 8% of body weight (5-6 Liters in males, 4-5 Liters in females).

    Physiology - Vasomotion

    • Metarterioles and precapillary sphincters are not innervated.
    • Capillary blood flow is regulated by vasomotion (based on oxygen levels).
    • Increased O2 causes precapillary sphincters to close, decreasing blood flow through capillaries.
    • Decreased O2 causes precapillary sphincters to open, increasing blood flow.

    Blood

    • Blood is composed of plasma, and blood cells.
    • Plasma is mostly water, and contains proteins (mostly 7% protein).
    • Plasma is the supernatant found above cellular components of blood when in a hematocrit tube.

    Fluid Exchange

    • Blood pressure forces fluid out of capillaries (capillary hydrostatic pressure)
    • Osmotic pressure of plasma proteins draws fluid into the capillaries.
    • Interstitial fluid pressure and interstitial fluid colloid osmotic pressure (negative, and tend to push fluid out of capillaries) affect fluid movement.
    • Fluid exchange across capillary walls represents balance of forces.
    • Filtration and absorption rate in this fluid exchange is approximately 1.7-3.5 ml/min and from 2.5-5.0 liters/day.
    • About 10% of fluid is lost from the body and must be reabsorbed into the circulatory system by lymphatic vessels.

    Overview of Systemic Blood Circulation and Lymphatic System

    • Fluid from exchange processes remains in the interstitial tissue.
    • Lymphatic system reabsorbs this fluid, returning it to circulation, and is also a factor in inflammation detection.

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    Description

    Test your knowledge on the circulatory system and its components with this quiz. Questions cover blood flow mechanisms, vessel structure, and the characteristics of arteries and veins. Challenge yourself to understand the nuances of capillary beds, vessel layers, and the blood composition.

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