Objective 2
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Questions and Answers

Which of the following is NOT a type of extracellular fluid?

  • Interstitial fluid
  • Plasma
  • Transcellular fluid
  • Intracellular fluid (correct)
  • Which of these mechanisms requires energy to move substances across cell membranes?

  • Active transport (correct)
  • Osmosis
  • Diffusion
  • Filtration
  • Which of the following is a waste product measured to assess kidney function?

  • Creatinine (correct)
  • Glucose
  • Sodium
  • Blood Urea Nitrogen (BUN)
  • A patient with high blood pressure might have a problem with which of the following?

    <p>Hydrostatic pressure (C)</p> Signup and view all the answers

    A solution with a higher concentration of solutes relative to another solution is considered:

    <p>Hypertonic (B)</p> Signup and view all the answers

    What is the body's ability to maintain a stable internal environment called?

    <p>Homeostasis (A)</p> Signup and view all the answers

    Which of the following is a condition where there is a decrease in fluid volume in the body?

    <p>Fluid volume deficit (C)</p> Signup and view all the answers

    Which of the following is NOT a buffer in the body?

    <p>Glucose (B)</p> Signup and view all the answers

    Which of these conditions is characterized by a decrease in blood plasma volume?

    <p>Hypovolemia (B)</p> Signup and view all the answers

    Which condition is most likely to result from excessive phosphate intake?

    <p>Hyperphosphatemia (B)</p> Signup and view all the answers

    What is the term for the pressure exerted by proteins in blood plasma that draws water into the circulatory system?

    <p>Oncotic pressure (C)</p> Signup and view all the answers

    A solution with the same concentration of solutes as another solution is considered:

    <p>Isotonic (A)</p> Signup and view all the answers

    Which of these is NOT a potential cause of hypocalcemia?

    <p>Hyperparathyroidism (A)</p> Signup and view all the answers

    What is the term for the movement of water across a semipermeable membrane from an area of lower solute concentration to an area of higher solute concentration?

    <p>Osmosis (C)</p> Signup and view all the answers

    What is the term for the fluid within cells?

    <p>Intracellular fluid (D)</p> Signup and view all the answers

    Which of these conditions is most likely to result from chronic alcoholism?

    <p>Hypomagnesemia (A)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of fluid overload (hypervolemia)?

    <p>Weight loss (B)</p> Signup and view all the answers

    What is the primary function of aldosterone in regulating fluid balance?

    <p>Increases sodium and water reabsorption in the kidneys (C)</p> Signup and view all the answers

    Which of the following is an example of a transcellular fluid?

    <p>Cerebrospinal fluid (C)</p> Signup and view all the answers

    Which type of intravenous fluid is primarily used to treat dehydration and shock?

    <p>Isotonic fluids (B)</p> Signup and view all the answers

    How do diuretics affect fluid balance in the body?

    <p>They decrease sodium and water reabsorption in the kidneys. (A)</p> Signup and view all the answers

    Which of the following factors contributes to fluid shifts in the body?

    <p>Changes in hydrostatic and oncotic pressures (A)</p> Signup and view all the answers

    What is the primary function of antidiuretic hormone (ADH) in fluid regulation?

    <p>Increases water reabsorption in the kidneys (C)</p> Signup and view all the answers

    A patient with severe dehydration is likely to exhibit which of the following signs?

    <p>Decreased urine output and concentrated urine (B)</p> Signup and view all the answers

    Which of the following is a sign that is NOT associated with Fluid Volume Deficit?

    <p>Bounding pulse (D)</p> Signup and view all the answers

    What is a possible cause of Hypernatremia?

    <p>Dehydration (B)</p> Signup and view all the answers

    Which of the following fluids is classified as hypotonic?

    <p>0.45% NaCl (Half Normal Saline) (C)</p> Signup and view all the answers

    Which of the following is NOT a sign of fluid volume excess?

    <p>Weight loss (A)</p> Signup and view all the answers

    What would be the MOST appropriate management for an individual experiencing hypernatremia?

    <p>Administering a hypotonic solution (C)</p> Signup and view all the answers

    Which of the following foods is a rich source of potassium?

    <p>Bananas (B)</p> Signup and view all the answers

    Which of the following is NOT a common cause of hypokalemia?

    <p>Excessive potassium intake (C)</p> Signup and view all the answers

    What is a potential cause of hypokalemia?

    <p>Diuretics (D)</p> Signup and view all the answers

    A patient with a low calcium level is experiencing muscle cramps and tingling. What is the likely cause?

    <p>Hypocalcemia (D)</p> Signup and view all the answers

    Which of these electrolytes is directly involved in muscle contraction?

    <p>Potassium (D)</p> Signup and view all the answers

    Which electrolyte imbalance is characterized by thirst, confusion, and muscle twitching?

    <p>Hypernatremia (A)</p> Signup and view all the answers

    What is a potential management strategy for hyperkalemia?

    <p>Diuretics (D)</p> Signup and view all the answers

    Which of these symptoms is NOT typically associated with hypomagnesemia?

    <p>Constipation (C)</p> Signup and view all the answers

    Which electrolyte imbalance is often linked to excessive water intake?

    <p>Hyponatremia (C)</p> Signup and view all the answers

    A patient is showing symptoms of fatigue, muscle weakness, and cardiac arrhythmias. What is the likely electrolyte imbalance?

    <p>Hyperkalemia (C)</p> Signup and view all the answers

    In what situation would a patient be considered to have a partially compensated acid-base imbalance?

    <p>The pH is abnormal, and the levels of CO₂ and HCO₃⁻ are abnormal. (C)</p> Signup and view all the answers

    Which of the following conditions is MOST likely to cause respiratory acidosis?

    <p>Chronic obstructive pulmonary disease (COPD) (D)</p> Signup and view all the answers

    What is the primary function of the renal system in regulating acid-base balance?

    <p>Excreting or reabsorbing H⁺ and HCO₃⁻ (D)</p> Signup and view all the answers

    Which of the following conditions is MOST LIKELY to lead to metabolic alkalosis?

    <p>Excessive use of antacids (A)</p> Signup and view all the answers

    Which of the following is NOT considered a potential cause of respiratory alkalosis?

    <p>Hypoventilation (C)</p> Signup and view all the answers

    What is the primary purpose of a crystalloid solution?

    <p>To replace fluids lost through vomiting, diarrhea, or sweating (C)</p> Signup and view all the answers

    What is the main concern associated with IV infiltration?

    <p>Pain and swelling at the IV site, potentially leading to tissue damage (D)</p> Signup and view all the answers

    Which of the following actions is MOST important to prevent phlebitis during IV therapy?

    <p>Keeping the IV site clean and dry, and checking for signs of inflammation (B)</p> Signup and view all the answers

    Flashcards

    Active Transport

    Movement of ions across a membrane from low to high concentration, requiring energy (ATP).

    Blood Urea Nitrogen (BUN)

    A measure of nitrogen in blood from urea, used to assess kidney function.

    Cations & Anions

    Cations are positively charged ions, while anions are negatively charged ions.

    Buffers

    Substances that maintain pH balance by neutralizing excess acids or bases.

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    Fluid Volume Deficit (FVD)

    Condition of decreased fluid volume in the body, often due to dehydration or blood loss.

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    Fluid Volume Excess (FVE)

    Condition of increased fluid volume in the body, often due to heart failure or kidney disease.

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    Hypernatremia

    Elevated sodium levels in the blood, often due to dehydration or excessive salt intake.

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    Hyponatremia

    Low sodium levels in the blood, often due to excessive water intake or loss of sodium.

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    Hypokalemia

    Low potassium levels in the blood caused by diuretics or loss through vomiting/diarrhea.

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    Hypercalcemia

    Elevated calcium levels in the blood, often due to hyperparathyroidism or malignancy.

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    Hypocalcemia

    Low calcium levels in the blood, typically from hypoparathyroidism or vitamin D deficiency.

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    Hyperphosphatemia

    Elevated phosphate levels in the blood, often due to kidney failure or excessive intake.

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    Hypovolemia

    A decrease in blood plasma volume due to dehydration or blood loss.

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    Edema

    The accumulation of fluid in interstitial spaces, causing swelling.

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    Interstitial Space

    The space between cells in tissue, filled with interstitial fluid.

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    Osmosis

    The movement of water across a membrane from low to high solute concentration.

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    First Spacing

    Normal distribution of body fluids within the compartments.

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    Second Spacing

    Abnormal accumulation of fluid in interstitial spaces, known as edema.

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    Third Spacing

    Fluid accumulation in areas where it cannot be easily exchanged, like ascites.

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    Transcellular Fluid

    Fluid contained within epithelial-lined spaces such as CSF, pleural fluid, and synovial fluid.

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    Fluid Deficit (Dehydration)

    Condition characterized by dry mucous membranes, decreased skin turgor, and low urine output.

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    Fluid Overload (Hypervolemia)

    Excessive fluid in the body, leading to edema, weight gain, and shortness of breath.

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    Aldosterone

    Hormone that increases sodium and water reabsorption in kidneys, raising blood volume.

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    Isotonic Fluids

    IV fluids that have the same osmotic pressure as body fluids, used to treat dehydration.

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    Partially Compensated

    pH is abnormal, with both CO₂ and HCO₃⁻ being abnormal.

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    Fully Compensated

    pH is normal, but CO₂ and HCO₃⁻ are both abnormal.

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    Respiratory Acidosis

    Condition caused by hypoventilation, leading to CO₂ retention.

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    Respiratory Alkalosis

    Condition caused by hyperventilation resulting in CO₂ loss.

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    Metabolic Acidosis

    Condition due to acid accumulation or bicarbonate loss.

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    Metabolic Alkalosis

    Condition due to bicarbonate accumulation or acid loss.

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    Colloid Solution

    Solution with large molecules; does not cross membranes, expands plasma volume.

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    Crystalloid Solution

    Solution with small molecules; passes through membranes for fluid replacement.

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    Hypertonic Fluids

    Fluids with higher osmolarity than blood, drawing water out of cells.

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    Hypotonic Fluids

    Fluids with lower osmolarity than blood, causing water to enter cells.

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    Fluid Volume Deficit

    A state with dry mucous membranes, reduced skin turgor, and low urine output.

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    Fluid Volume Excess

    A state with edema, weight gain, and hypertension due to excess fluids.

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    Foods Rich in Iron

    Examples include red meat, beans, and spinach; vital for blood health.

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    Hypernatremia Causes

    Caused by dehydration, excessive salt intake, and some medications.

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    Hyponatremia Causes

    Caused by excessive water intake, diuretics, and heart failure.

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    Hypermagnesemia

    High magnesium levels in the blood, often due to kidney failure.

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    Hypomagnesemia

    Low magnesium levels in the blood, often due to malnutrition or alcoholism.

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    Dehydration

    Loss of body fluids often leading to electrolyte imbalances like hypernatremia.

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    Fluid Management

    Strategies to address electrolyte imbalances include hydration and dietary modifications.

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    Study Notes

    Fluid and Electrolyte Key Terms and Concepts

    • Active Transport: Movement of ions/molecules across a cell membrane from lower to higher concentration, requiring energy (ATP).
    • Blood Urea Nitrogen (BUN): Measures nitrogen in blood from waste product urea, used to assess kidney function.
    • Cations and Anions: Cations are positively charged ions (e.g., Na+, K+), anions are negatively charged ions (e.g., Cl-, HCO3-).
    • Buffers: Substances that maintain blood pH by neutralizing excess acids/bases.
    • Creatinine: Muscle metabolism waste product, measured to assess kidney function.
    • Diffusion: Passive movement of molecules/ions from higher to lower concentration.
    • Extracellular Fluid (ECF): Fluid outside cells, including interstitial fluid, plasma, and transcellular fluid.
    • Filtration: Process where water and solutes are forced through a membrane by hydrostatic pressure.
    • Fluid Volume Deficit (FVD): Condition of decreased fluid volume, often due to dehydration or blood loss.
    • Fluid Volume Excess (FVE): Condition of increased fluid volume, often due to heart failure or kidney disease.
    • Homeostasis: Body's ability to maintain stable internal environment despite external changes.
    • Hydrostatic Pressure: Pressure exerted by a fluid due to its weight, important in fluid movement between compartments.
    • Hypertonic: Solution with higher solute concentration than another solution, causing cells to shrink.
    • Hypotonic: Solution with lower solute concentration than another solution, causing cells to swell.

    Additional Fluid/Electrolyte Concepts

    • Hyperkalemia: Elevated potassium levels in the blood, often due to kidney failure or excessive potassium intake.
    • Hypokalemia: Low potassium levels in the blood, often due to diuretics or excessive loss through vomiting/diarrhea.
    • Hypercalcemia: Elevated calcium levels in the blood, often due to hyperparathyroidism or malignancy.
    • Hypocalcemia: Low calcium levels in the blood, often due to hypoparathyroidism or vitamin D deficiency.
    • Hyperphosphatemia: Elevated phosphate levels in the blood, often due to kidney failure or excessive phosphate intake.
    • Hypophosphatemia: Low phosphate levels in the blood, often due to malnutrition or alcohol abuse.
    • Hypermagnesemia: Elevated magnesium levels in the blood, often due to kidney failure or excessive magnesium intake.
    • Hypomagnesemia: Low magnesium levels in the blood, often due to malnutrition or chronic alcoholism.
    • Hypovolemia: Decreased blood plasma volume, often due to dehydration or blood loss.
    • Hypervolemia: Increased blood plasma volume, often due to heart failure or kidney disease.
    • Interstitial Space: Space between cells in a tissue, filled with interstitial fluid.
    • Intracellular Fluid (ICF): Fluid within the cells.
    • Isotonic: Solution with same solute concentration as another solution, causing no net water movement.
    • Oncotic Pressure: Osmotic pressure exerted by proteins (primarily albumin) in blood plasma, pulling water into the circulatory system.
    • Osmosis: Movement of water across a semipermeable membrane from lower to higher solute concentration.
    • Osmotic Pressure: Pressure needed to prevent water flow across a semipermeable membrane.
    • Passive Transport: Movement of ions/molecules across a cell membrane without energy, driven by concentration gradients.

    Acid-Base Imbalances

    • Acid: Substance that releases hydrogen ions (H+) in solution.
    • Base: Substance that accepts hydrogen ions (H+) in solution.
    • Bicarbonate (HCO3-): Major buffer in the blood that helps maintain pH balance.
    • Carbon Dioxide (CO2): Metabolism waste product that combines with water to form carbonic acid.
    • Hydrogen Ions (H+): Positively charged ions that determine solution acidity.
    • Metabolic Acidosis: Condition with decreased blood pH due to acid accumulation or bicarbonate loss.
    • Metabolic Alkalosis: Condition with increased blood pH due to bicarbonate accumulation or acid loss.
    • Respiratory Acidosis: Condition with decreased blood pH due to CO2 accumulation from hypoventilation.
    • Respiratory Alkalosis: Condition with increased blood pH due to CO2 decrease from hyperventilation.
    • Arterial Blood Gas (ABG): Test measuring oxygen, carbon dioxide, and pH in arterial blood to assess respiratory and metabolic function.

    Fluid and Electrolyte Imbalance Clinical Manifestations

    • Hypernatremia: Thirst, confusion, muscle twitching, and seizures.
    • Hyponatremia: Nausea, headache, confusion, and seizures.
    • Hyperkalemia: Muscle weakness, cardiac arrhythmias, and fatigue.
    • Hypokalemia: Muscle weakness, cramps, and cardiac arrhythmias.
    • Hypercalcemia: Nausea, vomiting, constipation, and confusion.
    • Hypocalcemia: Muscle cramps, tingling, and seizures.
    • Hypermagnesemia: Nausea, vomiting, and muscle weakness
    • Hypomagnesemia: Muscle cramps, seizures, and cardiac arrhythmias

    Intravenous Fluids (IVF)

    • Isotonic Fluids: (e.g., 0.9% NaCl, Lactated Ringer's) Have same osmolarity as blood. Used for fluid volume deficit, dehydration, and shock.
    • Hypertonic Fluids: (e.g., 3% NaCl, Dextrose 10%) Have higher osmolarity than blood. Used to treat severe hyponatremia and cerebral edema.
    • Hypotonic Fluids: (e.g., 0.45% NaCl) Have lower osmolarity than blood. Used to treat hypernatremia and intracellular dehydration.

    Note: This summary covers many of the primary concepts. For a thorough understanding, additional research and class materials are recommended.

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    Questions cover various topics including extracellular fluids, kidney function, blood pressure, and the body's internal environment. Perfect for students learning about anatomy and physiology concepts.

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