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What is the main function of the cerebellum in the body?
What is the main function of the cerebellum in the body?
Which type of receptor is responsible for detecting light?
Which type of receptor is responsible for detecting light?
How does the endocrine system primarily communicate its signals?
How does the endocrine system primarily communicate its signals?
What is the primary purpose of melatonin in the body?
What is the primary purpose of melatonin in the body?
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Which part of the nervous system is responsible for involuntary responses like reflex arcs?
Which part of the nervous system is responsible for involuntary responses like reflex arcs?
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Which element is NOT typically maintained in homeostasis in the human body?
Which element is NOT typically maintained in homeostasis in the human body?
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What do motor neurons primarily do in the nervous system?
What do motor neurons primarily do in the nervous system?
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Which of the following components is NOT part of a reflex arc?
Which of the following components is NOT part of a reflex arc?
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What is the primary role of feedback mechanisms in regulating body systems?
What is the primary role of feedback mechanisms in regulating body systems?
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Which level of organization involves two or more types of tissues working together?
Which level of organization involves two or more types of tissues working together?
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What distinguishes a multicellular organism from a single-celled organism?
What distinguishes a multicellular organism from a single-celled organism?
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What is a tissue composed of?
What is a tissue composed of?
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Which of the following is an example of an organ system?
Which of the following is an example of an organ system?
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How do nerves and hormones contribute to body system integration?
How do nerves and hormones contribute to body system integration?
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Which component represents the highest level of organization?
Which component represents the highest level of organization?
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What is an example of how cells differentiate in multicellular organisms?
What is an example of how cells differentiate in multicellular organisms?
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What is the primary role of hormones in the integration of organs in animal bodies?
What is the primary role of hormones in the integration of organs in animal bodies?
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Which of the following best describes the speed of transmission for nervous signals?
Which of the following best describes the speed of transmission for nervous signals?
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What is a primary function of grey matter in the spinal cord?
What is a primary function of grey matter in the spinal cord?
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What distinguishes the central nervous system (CNS) from the peripheral nervous system?
What distinguishes the central nervous system (CNS) from the peripheral nervous system?
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Which of these statements about hormonal signaling is correct?
Which of these statements about hormonal signaling is correct?
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What is the primary purpose of the nervous system in communication within the body?
What is the primary purpose of the nervous system in communication within the body?
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How do hormones reach their target cells?
How do hormones reach their target cells?
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Which type of tissue in the spinal cord is responsible for transmitting signals from sensory receptors to the brain?
Which type of tissue in the spinal cord is responsible for transmitting signals from sensory receptors to the brain?
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What effect does high levels of melatonin have on the body?
What effect does high levels of melatonin have on the body?
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How does epinephrine affect blood flow during vigorous activity?
How does epinephrine affect blood flow during vigorous activity?
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What role does the hypothalamus play in the endocrine system?
What role does the hypothalamus play in the endocrine system?
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What is the primary function of ADH (antidiuretic hormone) released by the pituitary gland?
What is the primary function of ADH (antidiuretic hormone) released by the pituitary gland?
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What triggers the release of GnRH by the hypothalamus?
What triggers the release of GnRH by the hypothalamus?
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What is the primary result of vasoconstriction during epinephrine secretion?
What is the primary result of vasoconstriction during epinephrine secretion?
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What type of sensory information does the SA node receive?
What type of sensory information does the SA node receive?
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How does melatonin production change in response to light?
How does melatonin production change in response to light?
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What are the two components of acetylcholine?
What are the two components of acetylcholine?
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What role does acetylcholinesterase play in the synapse?
What role does acetylcholinesterase play in the synapse?
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What happens when the threshold potential is reached in a neuron?
What happens when the threshold potential is reached in a neuron?
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How does saltatory conduction affect nerve impulse speed?
How does saltatory conduction affect nerve impulse speed?
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Which of the following is true about neonicotinoids?
Which of the following is true about neonicotinoids?
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What effect does cocaine have on dopamine levels?
What effect does cocaine have on dopamine levels?
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What determines whether an action potential is initiated?
What determines whether an action potential is initiated?
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What is the primary effect of most exogenous chemicals on synaptic transmission?
What is the primary effect of most exogenous chemicals on synaptic transmission?
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What is the primary function of inhibitory neurotransmitters?
What is the primary function of inhibitory neurotransmitters?
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What emerges from the interaction of individual neurons in the brain?
What emerges from the interaction of individual neurons in the brain?
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What is the composition of tissue fluid that leaks from capillaries?
What is the composition of tissue fluid that leaks from capillaries?
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How do the adaptations of capillaries facilitate material exchange?
How do the adaptations of capillaries facilitate material exchange?
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What is the role of the sensory neurons with free nerve endings in relation to pain?
What is the role of the sensory neurons with free nerve endings in relation to pain?
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What characteristic of arteries allows them to maintain high blood pressure?
What characteristic of arteries allows them to maintain high blood pressure?
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What happens to waste materials in the tissue fluid?
What happens to waste materials in the tissue fluid?
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Which of the following best describes the state of consciousness?
Which of the following best describes the state of consciousness?
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Study Notes
Human Physiology IB Biology 12th
-
Unit Guiding Questions:
- What are the roles of nerves and hormones in integration of body systems?
- What are the roles of feedback mechanisms in regulation of body systems?
System Integration
- Definition: When components communicate and coordinate.
- Levels of Organization: Organelles, cells, tissues, organs, organ systems, and organisms.
- Emergent Properties: Individual parts combined create new functions.
Cells, Tissues, Organs, and Body Systems
- Hierarchy: Cell organelles -> cells -> tissues -> organs -> organ systems -> organisms
- Emergent Properties: Complex systems have functions that simple components alone do not possess. Examples include muscle cells, liver tissue, epithelium, heart, circulatory system, and the mammal.
Tissue
- Definition: A group of two or more different types of specialized cells with specific structures and functions working together and communicating.
- Example: Type I and Type II pneumocytes in alveolar tissue (lungs) performing gas exchange.
Organ
- Definition: A group of two or more types of tissues working together to perform a specific function in life.
- Example: Lung (alveolar tissue, cartilage tissue, ciliated epithelium tissue); Spongy and palisade mesophyll tissue in a leaf.
Organ System
- Definition: A group of organs working together to perform a function of life.
- Example: Digestive system (esophagus, stomach, intestines, pancreas, and other organs for digestion and nutrient absorption).
Organism
- Definition: A living thing made up of multiple integrated and interdependent systems.
- Example: Humans have 11 organ systems.
Integration of Organs
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Coordination: Requires:
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Communication:
- a. Hormones: Chemical substances released by the endocrine system, traveling through the bloodstream to affect target cells.
- b. Nerves: Electrical impulses rapidly transmitted by neurons to a specific location on muscle or glands.
- Transport of Materials: Blood/circulatory system carries substances between parts.
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Communication:
Hormones
- Definition: Chemical substances released by the endocrine system.
- Transport: Through bloodstream to the whole body.
- Action: Affect any cell with the proper receptor (target cell).
- Duration: Lasts until the hormone is broken down; slower than nervous signals.
Nervous Signals
- Definition: Electrical impulses (100 m/s) transmitted by neurons.
- Location: Specific muscle or glands.
- Speed: Rapid.
- Duration: Very short.
- Components: The nervous system consists of neurons (dendrites, axon, nucleus, soma, etc.) and synapses.
The Nervous System
- Composition: Neurons that carry electrical impulses, dendrites, motor end plates, and muscle cells.
- Typical Motor Neuron: Includes cell body, cytoplasm, nucleus, axon, impulse, myelin sheath, and synapse.
The Brain
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Central Information Integration:
- Receives information
- Stores information
- Processes information
- Sends signals to effectors if necessary.
The Spinal Cord
- Two Parts: Central Nervous System and Nerves
- CNS Function: Comprised of brain and spinal cord.
- White Matter Function: Transmits signals - from sensory receptors to the brain, and from the brain to other organs.
- Grey Matter Function: Contains cell bodies and synapses, processing information, decision making, and unconscious processes (e.g., digestive tract movement).
Transport of Materials and Energy
- Blood/Circulatory System: Transports materials throughout the body.
- Example: The digestive system passes intermediate products to other organs.
Involuntary Peristalsis (Intestine)
- Control: The enteric nervous system (ENS)
Sensory Receptors
- External Receptors: Touch, heat, light
- Internal Receptors: Stretch receptors, chemoreceptors
Brain Output
- Different Brain Parts Affect Different Organs: Many neurons in specific brain areas transmit to different effector organs.
Nerves
- Definition: Bundles of nerve fibers surrounded by a sheath.
- Function: Transmit signals in one direction only.
- Components: Sensory and motor neurons.
Reflex Arc (Example: Pain Reflex)
- Definition: Involuntary, rapid response to a stimulus.
- Process: Stimulus, receptor, sensory neuron, interneuron, motor neuron, effector organ.
Cerebellum
- Function: Coordination center that controls timing of muscle contractions, balance, posture, things that require muscle memory.
Homeostasis and Hormones
- Homeostasis: Maintaining stability in the internal environment between specific limits. Limits include pH, CO2, glucose levels, body temperature, and water balance.
- Endocrine System: Glands releasing hormones transported in blood.
Melatonin
- Gland: Pineal gland.
- Function: Controls circadian rhythms (sleep/wake cycles).
- Activity: High levels promote sleep, inhibited by light.
Hormone to Prepare for Vigorous Activity
- Hormone: Epinephrine (adrenaline).
- Adrenal Glands: Release epinephrine to prepare body for "fight or flight," increasing glucose, oxygen supply to skeletal muscles.
- Effects: Hydrolysis of glycogen = glucose. Increased diameter of bronchi/bronchioles: ventilation rates and tidal volume increase; Increase blood flow to liver and muscles; Decrease blood flow to gut and kidneys.
Hypothalamus and Pituitary Gland
- Connection: Hypothalamus attached to pituitary gland, connecting the nervous system and the endocrine system.
- Input: Receives input from other parts of the brain, temperature sensors, and blood glucose/solute concentrations.
Osmoregulation
- Senses: Detects solute concentration/osmolarity.
- Response: Prompts pituitary to release ADH to increase reabsorption in kidneys.
- Hormones: ADH (vasopressin)
Heart Rate Feedback
- SA Node: Connected to the medulla oblongata via the vagus and sympathetic nervous system.
- Feedback Loops: Chemoreceptors (sense pH, increase heart rate if pH is low); Baroreceptors (sense blood pressure, increase heart rate if blood pressure is low); Epinephrine can over ride these.
Ventilation Rate Feedback
- pH of blood: Normal = 7.35-7.45. Low pH = high CO2; drop in pH causes nerve signals to diaphragm and intercostals.
- Negative feedback loop: Relates to changes in ventilation rate during exercise.
- Spirometry used for measurements of rate and tidal volume during exercise.
Peristalsis Control
- Voluntary: Initiated by the central nervous system (CNS), swallowing and defecation (later in life).
- Involuntary: Controlled by the enteric nervous system (ENS), moving food and defecation (early in life).
Neural Signaling
- Nerve Impulse: Electrical signal passed between cells, along the same neuron or between neurons.
- Components: Axon of transmitting neuron, receiving neuron, chemical synapse, synaptic vesicle, neurotransmitter, synaptic cleft, receptor, axon terminals, soma, unmyelinated axon, terminal button, dendrites.
Membrane Potential
- Definition: Voltage created by imbalance of charges(ions).
- Rest: Inside of neuron is relatively negative (-70 mV); sodium ions on the outside.
- Action Potential: Reversal/restoration of electrical potential across plasma membrane.
Nerve Impulse
- Resting Potential: Electrical potential across a cell membrane when not propagating an impulse.
- Action Potential: Reversal/restoration of electrical potential between the inside and outside of a neuron.
Propagation of Action Potential (Nerve Impulse)
- Self-Propagating: Depolarization in one part triggers depolarization in the next due to the opening of voltage-gated channels in a one-way direction.
- Different Propagation Speeds: Myelinated neurons are faster (100 m/s) due to saltatory conduction, while unmyelinated neurons are slower (1 m/s).
Myelination and Saltatory Conduction
- Myelin Sheath: Acts as an insulator, forcing action potentials to "jump" between nodes of Ranvier.
- Saltatory Conduction: Action potentials jump from node to node in myelinated axons, which speeds up transmission.
Synaptic Transmission
- Synapse: Gap between cells where signals (neurotransmitters) are passed.
- Process: Electrical impulse to chemical neurotransmitter, neurotransmitters diffuse across the synapse, bind to the receptor, changes in ion channels, sufficient ion entry can cause action potential; neurotransmitter is removed.
Acetylcholine
- Neurotransmitter: Found between neurons and muscle cells; 2 parts: Acetyl (from respiration) and Choline (from diet).
- Breakdown: Acetylcholinesterase breaks it down quickly, choline reabsorbed to make more acetylcholine.
Threshold Potential
- Critical Level: Membrane potential must reach to initiate an action potential.
Propagation of Action Potential
- Local Currents: Movement of sodium ions between polarized and depolarised regions; causes depolarization in adjacent regions.
- Oscilloscope: Measures membrane potentials through electrodes.
Saltatory Conduction
- Mechanism: Jumping of the nerve impulse in myelinated neurons from node to node. Increases impulse speed.
- Schwann Cells: Act as insulators, carrying currents more quickly between nodes of Ranvier.
Exogenous Chemicals
- Nicotinoids: Insecticide similar to nicotine; irreversible binding to acetylcholine receptors causing paralysis/death in insects.
- Cocaine: Blocks dopamine reuptake causing dopamine buildup and euphoria.
Inhibitory Neurotransmitters
- Action: Some neurotransmitters make the membranes even more negative making it harder to send nerve impulses.
Synaptic Summation
- Excitatory/Inhibitory Summation: Excitatory inputs summate to reach the threshold, inhibitory inputs prevent.
Pain Perception
- Sensory Neurons: Have free nerve endings in the skin.
- Stimulus: Pain is detected; action potential generated.
- Pathway: Impulse travels to spinal column, then to brain.
- Response: Brain sends impulses to motor neurons to affect behavior.
Consciousness
- Definition: Simultaneous awareness of many things.
- Conditions: Reduced consciousness occurs during sleep and/or anesthesia.
Transport in Plants
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Water Transport:
- Transpiration (evaporation within the leaf)
- Osmosis (roots absorb water)
- Cohesion
- Adhesion
- Xylem Vessels: Dead, hollow vessels to move water;
- strengthened by lignin;
- transferred between cells through pits.
- Mass Flow - water transported as a continuous stream.
Adaptations of Plants' Transport Structures
- Xylem Vessels: Specialized for efficient water transport, being dead and hollow along with thickened walls of cellulose and lignin.
- Root hairs: Increased surface area for water absorption.
Coronary Artery Occlusion (Causes/Consequences)
- Atherosclerosis: Hardening and narrowing of arteries due to cholesterol deposits. Atheromas develop causing a reduction in vessel diameter.
- Occlusion Consequences: Myocardial tissue death; myocardial infarction(heart attack) due to restricted blood flow- oxygen/nutrient deprivation.
- Risk Factors: Smoking, obesity, lack of exercise, genetics, high blood pressure, diet high in saturated fats/salt, and age.
- Treatment: Bypass surgery, stent placement.
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Test your knowledge on the anatomy and physiology of the human body with this quiz. Questions cover the functions of the cerebellum, types of receptors, and the role of the endocrine system among others. Perfect for students and enthusiasts alike!