Human Anatomy and Physiology Quiz

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Questions and Answers

Which type of papillae are located in a V-shaped row at the back of the tongue?

  • Filiform
  • Foliate
  • Circumvallate (correct)
  • Fungiform

Which salivary gland is primarily responsible for secreting a watery fluid rich in enzymes?

  • Sublingual
  • Submandibular
  • Parotid (correct)
  • Buccal

Which type of cell produces the mucus component of saliva?

  • Endothelial cells
  • Mucous cells (correct)
  • Serous cells
  • Epithelial cells

What is the primary function of saliva?

<p>Moistening food and cleaning the mouth (B)</p> Signup and view all the answers

Which of the following is NOT a function of saliva?

<p>Production of antibodies (D)</p> Signup and view all the answers

What is the primary stimulus for gastrin secretion during the gastric phase?

<p>Presence of partially digested proteins and amino acids (A)</p> Signup and view all the answers

Which of the following is NOT a factor that inhibits gastric secretion during the intestinal phase?

<p>Release of intestinal gastrin (C)</p> Signup and view all the answers

What is the main role of gastrin in gastric secretion?

<p>Stimulates the release of hydrochloric acid (HCl) from parietal cells (D)</p> Signup and view all the answers

What happens when the pH of the stomach drops below 2?

<p>Gastrin secretion is inhibited (C)</p> Signup and view all the answers

Which phase of gastric secretion is characterized by reflexes initiated by sensory receptors in the head?

<p>Cephalic phase (A)</p> Signup and view all the answers

How does the sympathetic nervous system affect gastric secretion?

<p>It inhibits gastric secretion during times of stress (C)</p> Signup and view all the answers

What is the primary role of the stretch receptors in the gastric phase of secretion?

<p>They detect the distension of the stomach (A)</p> Signup and view all the answers

Which of these statements is true regarding the intestinal phase of gastric secretion?

<p>It is primarily inhibitory and lasts for a short period (D)</p> Signup and view all the answers

What type of connective tissue covers the visceral peritoneum?

<p>Areolar connective tissue (C)</p> Signup and view all the answers

Which of the following is NOT a function of the tongue?

<p>Secretion of digestive enzymes (C)</p> Signup and view all the answers

What is the difference between the adventitia and the serosa?

<p>The adventitia is a layer of connective tissue that binds an organ to surrounding tissues, while the serosa is a layer of connective tissue that covers an organ. (C)</p> Signup and view all the answers

What is the function of the submucosal nerve plexus?

<p>It regulates the secretion of digestive enzymes. (C)</p> Signup and view all the answers

Which of the following is NOT a component of the enteric nervous system?

<p>Sympathetic nervous system (C)</p> Signup and view all the answers

What is the role of the myenteric nerve plexus?

<p>Regulation of the smooth muscle that controls digestive tract motility. (B)</p> Signup and view all the answers

Which of the following statements about the enteric nervous system is TRUE?

<p>It functions independently of the central nervous system, but has connections to it. (C)</p> Signup and view all the answers

What is the role of the hepatic portal circulation?

<p>Filtering blood from the digestive organs before it reaches the heart (B)</p> Signup and view all the answers

What type of stimuli provoke digestive activity?

<p>Both chemical and mechanical stimuli (C)</p> Signup and view all the answers

What is the function of the orbicularis oris muscle?

<p>Closing the mouth and forming the lips (B)</p> Signup and view all the answers

What is the function of the hard palate?

<p>Creating friction against the tongue to help with chewing (B)</p> Signup and view all the answers

What is the name of the structure that closes off the nasopharynx during swallowing?

<p>Uvula (C)</p> Signup and view all the answers

What is a bolus?

<p>A mass of chewed food (B)</p> Signup and view all the answers

What is the name of the condition in which a child is born with an extremely short lingual frenulum?

<p>Ankyloglossia (B)</p> Signup and view all the answers

Which of the following is NOT a part of the oral cavity?

<p>Pharynx (C)</p> Signup and view all the answers

What is the function of the buccinator muscles?

<p>Helping to form the cheeks (B)</p> Signup and view all the answers

What is the primary function of the 2.H+-K+ ATPase pump in gastric parietal cells?

<p>Transporting protons (H+) into the lumen of the stomach (B)</p> Signup and view all the answers

Which of these is the correct sequence of events when the stomach is filled?

<p>Receptive relaxation, Gastric accommodation, Stomach distension, Increase in pressure (D)</p> Signup and view all the answers

Which of the following is NOT a factor contributing to the mucosal barrier in the stomach?

<p>The presence of pepsinogen in the gastric juice (B)</p> Signup and view all the answers

What is the role of enterogastrones in the intestinal phase of digestion?

<p>They inhibit gastric secretion to protect the intestines from being overwhelmed. (D)</p> Signup and view all the answers

Which of these factors can increase contractile activity in the stomach?

<p>Increase in the release of the hormone cholecystokinin (CCK) (A)</p> Signup and view all the answers

What is the primary role of the HCO3- ion in the stomach?

<p>To neutralize the acidic environment of the stomach lumen (A)</p> Signup and view all the answers

What contributes to the basic electrical rhythm (BER) of stomach contractions?

<p>Enteric pacemaker cells (B)</p> Signup and view all the answers

Which of the following substances is primarily responsible for the denaturation of proteins in the stomach?

<p>Hydrochloric acid (HCl) (D)</p> Signup and view all the answers

What is the primary role of the pyloric valve?

<p>To regulate the flow of chyme from the stomach into the duodenum. (A)</p> Signup and view all the answers

Which of the following is the primary function of the enzyme rennin in infants?

<p>Digestion of proteins, specifically casein (C)</p> Signup and view all the answers

Which of the following is NOT a mechanism involved in the regulation of gastric secretion?

<p>Mechanical stimulation by food (A)</p> Signup and view all the answers

Which of the following is NOT a mechanism of the enterogastric reflex?

<p>The release of secretin and cholecystokinin (CCK) by duodenal cells (D)</p> Signup and view all the answers

Why is the stomach's ability to accommodate food important?

<p>To prevent undue pressure buildup as food enters the stomach (A)</p> Signup and view all the answers

Which of the following hormones stimulates both enzyme and HCl secretion in the stomach?

<p>Gastrin (D)</p> Signup and view all the answers

Which of the following drugs can reduce acid secretion in the stomach by blocking histamine receptors?

<p>H2 receptor antagonists (B)</p> Signup and view all the answers

What is the approximate frequency of peristaltic waves in the stomach?

<p>3 waves per minute (B)</p> Signup and view all the answers

Which of the following is a consequence of the deficiency of intrinsic factor in the stomach?

<p>Pernicious anemia (D)</p> Signup and view all the answers

What is the primary function of the muscularis externa in the esophagus?

<p>Movement of food from the mouth to the stomach (C)</p> Signup and view all the answers

What is the structural difference between the esophagus and the stomach, in terms of their linings?

<p>The esophagus has a stratified squamous epithelium, while the stomach has a simple columnar epithelium. (A)</p> Signup and view all the answers

Which layer of the stomach is responsible for churning and mixing food with gastric juices?

<p>Muscularis externa (C)</p> Signup and view all the answers

What is the primary function of the parietal cells in the stomach?

<p>Secretion of hydrochloric acid (HCl) and intrinsic factor (B)</p> Signup and view all the answers

Where does the esophagus transition to the stomach?

<p>Cardiac sphincter (C)</p> Signup and view all the answers

Which cell type in the stomach secretes pepsinogen?

<p>Chief cells (C)</p> Signup and view all the answers

What is the function of the enterochromaffin-like (ECL) cells in the stomach?

<p>Secretion of histamine (B)</p> Signup and view all the answers

Which hormone is primarily responsible for stimulating gastric motility?

<p>Gastrin (B)</p> Signup and view all the answers

What is the role of the pyloric sphincter in digestion?

<p>It controls the movement of food from the stomach to the small intestine. (A)</p> Signup and view all the answers

Which of the following is NOT a region of the stomach?

<p>Duodenum (C)</p> Signup and view all the answers

Which of the following is the name of the membrane that connects the lesser curvature of the stomach to the liver?

<p>Lesser omentum (D)</p> Signup and view all the answers

What is the name of the folds in the stomach lining that increase surface area?

<p>Rugae (D)</p> Signup and view all the answers

What is the name of the enzyme secreted by chief cells that helps break down proteins?

<p>Pepsin (D)</p> Signup and view all the answers

What is the primary function of the gastric glands in the stomach?

<p>Produce gastric juice (A)</p> Signup and view all the answers

Flashcards

Foliate Papillae

Papillae located on the lateral aspects of the posterior tongue; contain taste buds.

Filiform Papillae

Whitish papillae that provide roughness for friction on the tongue; do not contain taste buds.

Fungiform Papillae

Reddish, scattered papillae across the tongue that contain taste buds.

Circumvallate Papillae

Large, V-shaped papillae located at the back of the tongue; contain taste buds.

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Salivary Glands

Glands that secrete saliva to cleanse the mouth, aid taste, and begin food breakdown.

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Serosa

Outermost protective layer of abdominal organs, made of areolar connective tissue and mesothelium.

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Visceral peritoneum

Another name for serosa that covers the organs in the abdominal cavity.

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Adventitia

A fibrous connective tissue layer that binds the esophagus to surrounding tissues.

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Retroperitoneal organs

Organs that have both adventitia and serosa, facing the peritoneal cavity and dorsal body wall.

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Splanchnic circulation

Blood supply system serving the digestive organs via branches of the abdominal aorta.

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Celiac trunk

A major artery that supplies blood to the liver, spleen, and stomach.

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Hepatic portal circulation

Venous return system from the digestive viscera that goes to the liver.

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Enteric Nervous System (ENS)

The gut brain includes enteric neurons that regulate GI tract motility.

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Submucosal nerve plexus

Plexus containing neurons that regulate glands and smooth muscle in the mucosa.

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Myenteric nerve plexus

Nerve plexus located between muscle layers that controls GI tract motility.

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Short reflexes

Reflexes initiated by stimuli inside the GI tract, involving the ENS.

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Hormonal controls of digestion

Controls initiated by hormones from the stomach and small intestine affecting digestion.

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Buccal cavity

The mouth area bounded by lips, cheeks, and palate, starting digestion.

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Tongue functions

Controls food mixing, forming bolus, initiating swallowing, and taste sensation.

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Ankyloglossia

A condition where the lingual frenulum is short, affecting tongue movement.

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Intestinal phase inhibition

Prevents excess chyme or acidity in the intestine.

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Enterogastric reflex

Neural reflex that inhibits stomach acid secretion via duodenum.

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Enterogastrones

Hormones secreted by duodenal cells that reduce gastric secretion.

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Receptive relaxation

Reflex that allows stomach to relax when food enters.

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Gastric accommodation

Smooth muscle's ability to stretch without increased tension.

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Basic electrical rhythm (BER)

Cyclic slow waves that regulate stomach contractions.

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Peristaltic waves

Wave-like muscle contractions that move chyme in the stomach.

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Gastric contractile activity

Strength and frequency of stomach contractions affected by distension and gastrin.

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Cephalic Phase

The initial phase of gastric secretion before food reaches the stomach, triggered by sensory stimuli.

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Gastric Phase

The phase where food in the stomach stimulates secretion of gastric juices for 3-4 hours; provides 2/3 of gastric juice.

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Stimuli for Gastric Phase

Stretch receptors and chemical stimuli in the stomach that trigger gastrin secretion and HCl production.

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Role of Gastrin

A hormone that stimulates gastric acid secretion and promotes digestive enzyme release.

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Buffering Action

ingested proteins increase pH, enhancing gastrin secretion and HCl release.

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Inhibition of Gastric Secretion

Low pH (<2) and sympathetic stimulation inhibit gastrin secretion during stress.

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Intestinal Phase

Phase beginning when partially digested food enters small intestine; includes brief stimulation then inhibition.

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Inhibitory Factors of Intestinal Phase

Distension and chemical compositions in the duodenum that inhibit gastric secretion.

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Carbonic Acid

H2CO3 that dissociates into HCO3- and H+ in solution.

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H+-K+ ATPase

An enzyme that pumps H+ ions into the lumen and K+ ions into cells.

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Bicarbonate-rich mucus

A thick coating that buffers stomach acid and protects epithelial cells.

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Tight Junctions

Connections between epithelial cells preventing leakage of gastric juice.

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Intrinsic Factor

A secretion needed for vitamin B12 absorption essential for red blood cell maturation.

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Gastrin

A hormone that stimulates gastric secretion of enzymes and HCl.

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Vagus Nerve

A nerve that stimulates gastric secretion when activated.

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Chyme

Partially digested food that is delivered to the small intestine.

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Pernicious Anemia

A condition caused by a lack of intrinsic factor leading to insufficient vitamin B12.

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Gastric Juice Regulation

Control of gastric juice secretion through neural and hormonal mechanisms.

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Layers of the Esophagus

The esophagus has four layers: mucosa, submucosa, muscularis externa, and adventitia.

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Esophageal Mucosa

Contains stratified squamous epithelium (SSE) that transitions to simple columnar epithelium at the stomach.

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Esophageal Glands

Glands in the submucosa secrete mucus for bolus movement during swallowing.

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Muscularis externa of Esophagus

Composed of skeletal muscles in the upper part, mixed in the middle, and smooth muscle in the lower part.

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Adventitia vs Serosa

The esophagus has adventitia instead of serosa, anchoring it to surrounding structures.

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Deglutition

Swallowing process, involving the passage of food from mouth to stomach.

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Pharyngeal phase

The involuntary stage of swallowing, controlled by the vagus nerve.

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Peristalsis

Involuntary muscle contractions that propel food through the esophagus.

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Esophageal Sphincters

Two sphincters (upper and lower) regulate food passage into the stomach.

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Stomach Functions

The stomach serves as a storage tank and continues breaking down food into chyme.

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Regions of the Stomach

Four major regions: cardia, fundus, body, and pyloric part.

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Gastric Glands Function

Gastric pits lead to glands producing gastric juice, including HCl and enzymes.

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Hydrochloric Acid Role

HCl denatures proteins, activates pepsin, and kills bacteria in the stomach.

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Alkaline Tide

The process where the increase of bicarbonate in blood occurs post food intake.

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Types of Gastric Cells

Includes mucous neck cells, parietal cells, chief cells, and enteroendocrine cells.

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Study Notes

Digestive System Overview

  • The digestive system's function is to take in food, break it down into nutrients, absorb those nutrients into the bloodstream, and eliminate any indigestible remains.
  • This process involves four main steps: ingestion, digestion, absorption, and elimination.
  • Digestive organs include the oral cavity, salivary glands, esophagus, stomach, pancreas, gallbladder, small intestine, and large intestine.
  • Accessory organs like teeth, tongue and liver support the digestive process.

Digestive System Structures

  • The alimentary canal is a continuous tube extending from mouth to anus including the oral cavity, pharynx, esophagus, stomach, small intestine, and large intestine
  • Accessory digestive organs include teeth, tongue, salivary glands, liver, gallbladder, and pancreas.
  • The peritoneum is a serous membrane lining the abdominal cavity, with visceral peritoneum covering organs and parietal peritoneum lining the body wall.
  • The peritoneal cavity is a fluid-filled space between these membranes lubricating mobile organs.
  • Mesentery, another double layer of peritoneum, holds organs in place and supports blood vessels/nerves.

Histological Features of the Alimentary Canal

  • Digestive organs have four basic layers (tunics): mucosa, submucosa, muscularis externa, and serosa/adventitia.
  • The mucosa lines the lumen, secretes digestive enzymes and hormones, absorbs nutrients, and protects the organ from pathogens.
  • Specialized cells like goblet cells produce mucus (for protection and movement).
  • The submucosa layer contains glands, blood vessels, and the submucosal nerve plexus.
  • Muscularis externa layers (circular and longitudinal) control peristalsis and segmentation, vital for moving food.
  • The serosa/adventitia is the outermost layer, a protective covering.

Blood Supply

  • Splanchnic circulation is the arterial supply to digestive organs, branch from the abdominal aorta.
  • Major arteries feeding the digestive organs include hepatic, splenic, and mesenteric arteries.
  • Venous return, which carries absorbed nutrients, is indirect via hepatic portal circulation - not directly from digestive viscera into vena cava.

Enteric Nervous System (ENS)

  • The GI tract has its own nervous system called the ENS.
  • The ENS is composed of myenteric nerve plexus (between layers of muscularis externa) and submucosal nerve plexus (in submucosa).
  • It regulates motility and local secretions through short reflexes (primarily within the ENS itself).
  • The ENS receives innervation from the central nervous system (via the autonomic nervous system).

Digestive Processes in the Mouth

  • Mastication (chewing) breaks down food into smaller particles, mixes with saliva.
  • Salivary enzymes (amylase & lipase) begin the chemical breakdown of carbohydrates and lipids respectively.

Digestive Processes in the Pharynx and Esophagus

  • Swallowing (deglutition), involving voluntary buccal phase (chewing) and involuntary pharyngeal-esophageal phase (propulsion), transports food from mouth to stomach
  • Two esophageal sphincters regulate the passage of food into the stomach (cardioesophageal).
  • Peristaltic waves in the esophagus propel food to the stomach.

Digestive Processes in the Stomach

  • The stomach mixes and churns food into a paste-like chyme.
  • Gastric secretions (HCl, mucus, enzymes) aid in protein digestion, denaturing proteins and killing bacteria in the food.
  • The stomach absorbs lipid-soluble substances (e.g. alcohol, aspirin), but not most other nutrients.
  • The stomach has mechanical and chemical functions; physically mixing food and chemically breaking down proteins.
  • The stomach regulates gastric emptying rate.

Regulation of Gastric Secretion & Motility

  • Distension of the stomach, chemical stimuli and hormones in the stomach or intestine trigger the release of gastric secretions and affect motility.
  • Gastric secretions are broken down into cephalic, gastric, and intestinal phases; these involve neuronal and hormonal mechanisms for secretion.
  • The stomach muscles have a intrinsic ability to accommodate filling volumes.
  • Several factors inhibit gastric emptying; the presence of fatty, hypertonic, or acidic chyme in the duodenum trigger reflexes.

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