Human Anatomy and Physiology Chapter 9 Flashcards
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Questions and Answers

What are concentric contractions?

Isotonic contractions in which muscle shortens and does work like picking up a book.

What are eccentric contractions?

Isotonic contractions in which muscle generates force as it lengthens.

What does isometric mean in muscle contraction?

No movement; no shortening of muscle; cannot move a load.

What is muscle tone?

<p>Even relaxed muscles are almost always slightly contracted.</p> Signup and view all the answers

What role does phosphorylation play in muscle contraction?

<p>High energy storage molecule called creatine phosphate gives up phosphate to ADP to form ATP.</p> Signup and view all the answers

What is Anaerobic Respiration?

<p>Respiration that occurs without oxygen present.</p> Signup and view all the answers

What occurs during Aerobic Respiration?

<p>Glycolysis breaks down glucose and pyruvic acid enters mitochondria for complete breakdown.</p> Signup and view all the answers

What leads to muscle fatigue?

<p>ATP use exceeds ATP production and excessive accumulation of lactic acid.</p> Signup and view all the answers

What are the requirements for the resting state of muscles?

<p>Oxygen reserves must be replenished, lactic acid must be converted, glycogen stores replaced, and ATP reserves resynthesized.</p> Signup and view all the answers

What factors determine the force of muscle contraction?

<p>Number of muscle fibers stimulated, relative size of fibers, frequency of stimulation, and degree of muscle stretch.</p> Signup and view all the answers

What characterizes slow oxidative fibers?

<p>Slow contracting muscle that produces ATP through aerobic pathway and resists fatigue.</p> Signup and view all the answers

What are fast glycolytic fibers?

<p>Muscle fibers that use anaerobic pathways and tire quickly.</p> Signup and view all the answers

What happens during aerobic exercise?

<p>Increases number of mitochondria within muscle fibers and synthesizes more myoglobin.</p> Signup and view all the answers

What is disuse atrophy?

<p>Muscle gets too small due to lack of use.</p> Signup and view all the answers

What is peristalsis?

<p>Alternating contraction and relaxation of smooth muscle layers.</p> Signup and view all the answers

What are varicosities in smooth muscle?

<p>Bulbous swellings of nerve fibers that release neurotransmitters.</p> Signup and view all the answers

Describe the NMJ of smooth muscle.

<p>Varicosities have neurotransmitters with clefts for many areas of reception.</p> Signup and view all the answers

What does the sarcoplasmic reticulum of smooth muscle lack?

<p>No sarcomeres, no T tubules.</p> Signup and view all the answers

What characterizes smooth muscle contraction?

<p>Calcium binds to calmodulin and activates myosin light chain kinase.</p> Signup and view all the answers

How is smooth muscle contraction regulated?

<p>Autonomic nerves release different neurotransmitters; some excite and some inhibit.</p> Signup and view all the answers

What is the definition of excitability?

<p>It can respond to a stimulus.</p> Signup and view all the answers

What does contractibility mean?

<p>If stimulated, it shortens and thickens.</p> Signup and view all the answers

Define extensibility.

<p>It has the ability to stretch past its normal length.</p> Signup and view all the answers

What is meant by elasticity in muscle tissue?

<p>It can convert back to its normal shape and size if extended or contracted.</p> Signup and view all the answers

Which of the following describes smooth muscle?

<p>Involuntary and found in hollow organs.</p> Signup and view all the answers

What characterizes cardiac muscle?

<p>Involuntary with striations and intercalated disks.</p> Signup and view all the answers

What are the main functions of muscle tissue?

<p>Generating heat and moving bones.</p> Signup and view all the answers

What is the composition of skeletal muscle?

<p>Skeletal muscle fibers, blood vessels, nerve fibers, connective tissue.</p> Signup and view all the answers

Define direct attachment of muscle.

<p>Either periosteum or perichondrium does the attachment.</p> Signup and view all the answers

What is an indirect attachment of muscle?

<p>Connective tissue extending beyond the end of the muscle to the bone.</p> Signup and view all the answers

What is a tendon?

<p>A rope-like extension of connective tissue.</p> Signup and view all the answers

What is an aponeurosis?

<p>Connective tissue that is flat sheet-like.</p> Signup and view all the answers

What does the term 'origin' refer to in muscle attachment?

<p>Attachment to an immovable bone.</p> Signup and view all the answers

Define epimysium.

<p>An overcoat of dense irregular connective tissue that surrounds the whole muscle.</p> Signup and view all the answers

What is the function of the perimysium?

<p>Surrounds each fascicle of muscle fibers.</p> Signup and view all the answers

Describe the endomysium.

<p>A wispy areolar connective tissue sheath surrounding each individual muscle fiber.</p> Signup and view all the answers

What is a fascicle?

<p>A collection of muscle fibers that bundles together to make a muscle.</p> Signup and view all the answers

What does sarcolemma refer to?

<p>The plasma membrane of a muscle cell.</p> Signup and view all the answers

Define sarcoplasm.

<p>Cytoplasm of a muscle cell containing glycosomes and myoglobin.</p> Signup and view all the answers

What are myofibrils?

<p>Rod-like structures running parallel to the muscle fiber's length.</p> Signup and view all the answers

What are glycosomes?

<p>Vesicles that contain glycogen as a storage medium.</p> Signup and view all the answers

What is the function of the sarcoplasmic reticulum?

<p>Regulates intracellular levels of ionic calcium.</p> Signup and view all the answers

Describe the H Zone.

<p>A lighter region at the midsection of a dark A band.</p> Signup and view all the answers

What does the M Line represent?

<p>It vertically bisects each H zone and is formed by proteins.</p> Signup and view all the answers

What is a Z disc?

<p>A darker area that is the midline interruption of a light I band.</p> Signup and view all the answers

Define sarcomere.

<p>The region of a myofibril between two successive Z discs.</p> Signup and view all the answers

What are myofilaments?

<p>Small structures within sarcomeres that contain actin or myosin.</p> Signup and view all the answers

What are thick filaments primarily composed of?

<p>Myosin.</p> Signup and view all the answers

What are thin filaments primarily composed of?

<p>Actin.</p> Signup and view all the answers

What are intermediate (desmin) filaments?

<p>They extend from Z discs and connect each myofibril to the next.</p> Signup and view all the answers

What is the composition of myofilaments?

<p>Primarily composed of myosin, some actin.</p> Signup and view all the answers

Describe myosin's structure.

<p>Each molecule consists of two heavy and four light polypeptide chains.</p> Signup and view all the answers

What happens during a cross bridge formation?

<p>Myosin heads link thick and thin filaments together during contraction.</p> Signup and view all the answers

What does actin provide in muscle cells?

<p>Active sites for myosin heads to attach during contraction.</p> Signup and view all the answers

Define regulatory proteins in thin filaments.

<p>Proteins that help regulate muscle contraction by binding to actin and tropomyosin.</p> Signup and view all the answers

What does the elastic filament do?

<p>Helps maintain organization of A band and spring back into place.</p> Signup and view all the answers

What is the function of T Tubule?

<p>Increase surface area for muscle contraction impulses.</p> Signup and view all the answers

What does the Z line signify?

<p>The end of the sarcomere, shared between two adjacent sarcomeres.</p> Signup and view all the answers

What is the A band?

<p>The entire length of the thick myofilament.</p> Signup and view all the answers

What is the I band?

<p>Where there are only thin myofilaments.</p> Signup and view all the answers

What does the sliding filament theory describe?

<p>Thin myofilaments slide over thick myofilaments during contraction.</p> Signup and view all the answers

What is the neuromuscular junction?

<p>The modification of sarcolemma where muscle fiber is adjacent to a neuron.</p> Signup and view all the answers

What is required for skeletal muscle fiber contraction?

<p>Must generate action potential and increase intracellular calcium levels.</p> Signup and view all the answers

What are synaptic vesicles?

<p>Membranous sacs containing neurotransmitters, such as acetylcholine.</p> Signup and view all the answers

Describe the neuromuscular junction process.

<p>Action potential opens calcium channels, triggering neurotransmitter release.</p> Signup and view all the answers

What is excitation-contraction coupling?

<p>The process where ACh triggers action potential and calcium release.</p> Signup and view all the answers

Define power stroke.

<p>The process where myosin heads pull thin myofilaments toward H zone.</p> Signup and view all the answers

What happens during muscle recovery?

<p>Calcium is pumped back into the sarcoplasmic reticulum, and muscle relaxes.</p> Signup and view all the answers

What is a twitch?

<p>A single, rapid, jerky response to a single stimulus.</p> Signup and view all the answers

What is a graded muscle response?

<p>Variations needed for proper control of skeletal movement.</p> Signup and view all the answers

What is wave or temporal summation?

<p>A phenomenon where rapid successive stimuli lead to stronger contractions.</p> Signup and view all the answers

Define unfused or incomplete tetanus.

<p>Sustained but quivering contraction due to constant stimulation.</p> Signup and view all the answers

What is complete tetanus?

<p>Maximal muscle tension with smooth, sustained contraction.</p> Signup and view all the answers

What does treppe refer to?

<p>Stronger contractions due to incomplete relaxation between stimuli.</p> Signup and view all the answers

What is isotonic contraction?

<p>Muscle contraction that produces movement.</p> Signup and view all the answers

Study Notes

Muscle Tissue Characteristics

  • Excitability: Muscle tissue can respond to stimuli, primarily nervous impulses.
  • Contractibility: Muscles can shorten and thicken when stimulated.
  • Extensibility: Muscles have the ability to stretch beyond their normal length.
  • Elasticity: Muscles can return to their original shape and size after being stretched or contracted.

Types of Muscle

  • Smooth Muscle: Involuntary muscle found in the walls of hollow organs; elongated cells without striations.
  • Cardiac Muscle: Striated, branched muscle with intercalated disks; it is involuntary.
  • Skeletal Muscle: Long, striated muscle cells arranged in parallel; voluntary and multinucleated.

Functions of Muscle Tissue

  • Movement and locomotion
  • Maintaining posture
  • Stabilizing joints
  • Generating heat through muscle activity

Structure of Skeletal Muscle

  • Composed of muscle fibers, blood vessels, nerve fibers, and connective tissue. Requires continuous oxygen and nutrient delivery.
  • Direct Attachment: Epimysium of muscle fuses with the periosteum of bone or perichondrium of cartilage.
  • Indirect Attachment: Tendons connect muscle to bone, extending beyond the muscle.
  • Tendons: Rope-like extensions of connective tissue, while Aponeurosis is a flat sheet-like structure.

Connective Tissue Sheaths

  • Epimysium: Dense connective tissue surrounding the entire muscle.
  • Perimysium and Fascicles: Fascicles are bundles of muscle fibers wrapped in perimysium.
  • Endomysium: Wispy connective tissue sheath surrounding individual muscle fibers.

Muscle Fiber Components

  • Sarcolemma: Plasma membrane of a muscle cell.
  • Sarcoplasm: Cytoplasm containing glycosomes (glycogen storage) and myoglobin (oxygen storage).
  • Myofibrils: Rod-like structures that account for muscle cell volume, containing sarcomeres (contractile units) and myofilaments.

Myofilaments

  • Thick Filaments: Composed of myosin, extending the entire length of the A band.
  • Thin Filaments: Consists of actin, extending across the I band.
  • Cross Bridge: Myosin heads link thick and thin filaments during contraction.

Sarcomere Structure

  • Z Disc: Midline interruption of I band; connects thin filaments.
  • H Zone: Lighter region in the A band, bisected by the M line.
  • Sliding Filament Theory: Thin filaments slide over thick filaments during contraction, shortening the muscle.

Excitation-Contraction Coupling

  • Action potential generation leads to muscle contraction through calcium release from the sarcoplasmic reticulum.
  • Calcium binds to troponin, allowing myosin heads to attach to actin for contraction.

Muscle Contraction Types

  • Twitch: Rapid, jerky response; a single contraction follows a single stimulus.
  • Graded Muscle Response: Variations in muscle movement strength, influenced by stimulus frequency and intensity.
  • Wave Summation: Successive stimuli cause a stronger contraction due to incomplete relaxation.
  • Tetanus: Sustained muscle contraction occurs when stimuli frequency increases.

Muscle Contraction Energy Sources

  • Aerobic Respiration: Generates high ATP through glycolysis and complete breakdown in mitochondria; requires continuous oxygen.
  • Anaerobic Respiration: Glycolysis leads to lactic acid accumulation in the absence of oxygen; generates less ATP quickly.
  • Phosphorylation: Creatine phosphate supplies phosphate to regenerate ATP quickly for short-term energy.

Muscle Fatigue and Recovery

  • Fatigue: Occurs when ATP usage exceeds production, leading to lactic acid buildup and ionic imbalances.
  • Recovery: Requires replenishing oxygen, converting lactic acid, resynthesizing glycogen, ATP, and creatine phosphate.

Muscle Characteristics

  • Muscle Tone: Even at rest, muscles maintain slight tension to stabilize joints and posture.
  • The force of muscle contractions depends on the number of crossbridges, stimulated fibers, fiber sizes, and stimulation frequency.### Muscle Physiology Basics
  • Muscle contraction strength increases with the number of stimulated fibers.
  • Larger muscle fibers generate stronger contractions, influenced by training and genetics.
  • Muscle fiber size can be modified through exercise, though individuals are born with a predetermined number of fibers.
  • Faster stimulation leads to stronger muscle contractions until optimal stretch is reached; excessive stretching hinders contraction.
  • Optimal overlap of thick and thin filaments (A) ensures effective contraction, while partial overlap (B) still allows for some contraction.

Muscle Fiber Types

  • Slow Oxidative Fibers
    • Contract slowly, utilize aerobic pathways for ATP production, high endurance, and rich in mitochondria.
    • Resilient to fatigue but have less power due to slower ATPase activity.
  • Fast Oxidative Fibers
    • Contract rapidly, also use aerobic pathways, resistant to fatigue.
    • Characteristics include a rich supply of myoglobin and capillaries, allowing for quick ATP production.
  • Fast Glycolytic Fibers
    • Rely on anaerobic pathways, produce less ATP quickly, and tire rapidly.
    • Characterized by large diameter and minimal mitochondria; suited for brief, intense activities.

Exercise Effects on Muscle

  • Aerobic Exercise
    • Increases mitochondrial numbers and myoglobin synthesis in muscle fibers.
    • Primarily enhances slow oxidative fibers, contributing to endurance through angiogenesis (new capillary formation).
  • Resistance Exercise
    • Focuses on anaerobic pathways and intensively loads muscles.
    • More significantly increases muscle fiber size than aerobic exercise, promoting hypertrophy.
    • Can convert some fast oxidative fibers to fast glycolytic fibers.

Muscle Atrophy

  • Disuse atrophy occurs when muscles weaken and shrink due to inactivity.
  • Prolonged disuse can lead to muscle tissue converting to fibrous connective tissue.

Smooth Muscle Structure

  • Smooth muscle fibers are smaller than skeletal fibers and lack connective tissue sheaths except for the endomysium.
  • Organized in layers: longitudinal for dilation and circular for constriction of tubes.
  • Features no motor end plates or structured neuromuscular junctions; uses varicosities to release neurotransmitters.

Smooth Muscle Physiology

  • Peristalsis
    • Smooth muscle layers contract and relax alternately, propelling contents through organ lumens.
  • Varicosities
    • Enlarged nerve fibers release neurotransmitters into synaptic clefts during smooth muscle activation.
  • Sarcoplasmic Reticulum
    • Lacks sarcomeres and T-tubules; instead, features caveoli for calcium concentration.
  • Myofilaments consist of both thick and thin components, arranged diagonally, and lack troponin.

Smooth Muscle Contraction

  • Triggered by neurotransmitter-induced action potentials that release calcium.
  • Calcium interacts with calmodulin, activating myosin light chain kinase to facilitate muscle contraction.
  • Involves calcium influx from both caveoli and extracellular space, leading to myosin activation and fiber shortening.

Regulation of Smooth Muscle Activity

  • Controlled by autonomic nerve neurotransmitters causing excitation or inhibition.
  • Influenced by chemical factors, such as oxytocin in labor and histamine during inflammation.
  • Somatic motor neurons release solely acetylcholine as a neurotransmitter.

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Explore key concepts from Chapter 9 of Human Anatomy and Physiology with these flashcards. Each card provides essential definitions of important terms, including excitability, contractibility, extensibility, and elasticity. Master these concepts for a deeper understanding of muscle function.

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