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Questions and Answers
What are concentric contractions?
What are concentric contractions?
Isotonic contractions in which muscle shortens and does work like picking up a book.
What are eccentric contractions?
What are eccentric contractions?
Isotonic contractions in which muscle generates force as it lengthens.
What does isometric mean in muscle contraction?
What does isometric mean in muscle contraction?
No movement; no shortening of muscle; cannot move a load.
What is muscle tone?
What is muscle tone?
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What role does phosphorylation play in muscle contraction?
What role does phosphorylation play in muscle contraction?
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What is Anaerobic Respiration?
What is Anaerobic Respiration?
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What occurs during Aerobic Respiration?
What occurs during Aerobic Respiration?
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What leads to muscle fatigue?
What leads to muscle fatigue?
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What are the requirements for the resting state of muscles?
What are the requirements for the resting state of muscles?
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What factors determine the force of muscle contraction?
What factors determine the force of muscle contraction?
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What characterizes slow oxidative fibers?
What characterizes slow oxidative fibers?
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What are fast glycolytic fibers?
What are fast glycolytic fibers?
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What happens during aerobic exercise?
What happens during aerobic exercise?
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What is disuse atrophy?
What is disuse atrophy?
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What is peristalsis?
What is peristalsis?
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What are varicosities in smooth muscle?
What are varicosities in smooth muscle?
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Describe the NMJ of smooth muscle.
Describe the NMJ of smooth muscle.
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What does the sarcoplasmic reticulum of smooth muscle lack?
What does the sarcoplasmic reticulum of smooth muscle lack?
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What characterizes smooth muscle contraction?
What characterizes smooth muscle contraction?
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How is smooth muscle contraction regulated?
How is smooth muscle contraction regulated?
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What is the definition of excitability?
What is the definition of excitability?
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What does contractibility mean?
What does contractibility mean?
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Define extensibility.
Define extensibility.
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What is meant by elasticity in muscle tissue?
What is meant by elasticity in muscle tissue?
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Which of the following describes smooth muscle?
Which of the following describes smooth muscle?
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What characterizes cardiac muscle?
What characterizes cardiac muscle?
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What are the main functions of muscle tissue?
What are the main functions of muscle tissue?
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What is the composition of skeletal muscle?
What is the composition of skeletal muscle?
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Define direct attachment of muscle.
Define direct attachment of muscle.
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What is an indirect attachment of muscle?
What is an indirect attachment of muscle?
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What is a tendon?
What is a tendon?
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What is an aponeurosis?
What is an aponeurosis?
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What does the term 'origin' refer to in muscle attachment?
What does the term 'origin' refer to in muscle attachment?
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Define epimysium.
Define epimysium.
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What is the function of the perimysium?
What is the function of the perimysium?
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Describe the endomysium.
Describe the endomysium.
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What is a fascicle?
What is a fascicle?
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What does sarcolemma refer to?
What does sarcolemma refer to?
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Define sarcoplasm.
Define sarcoplasm.
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What are myofibrils?
What are myofibrils?
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What are glycosomes?
What are glycosomes?
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What is the function of the sarcoplasmic reticulum?
What is the function of the sarcoplasmic reticulum?
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Describe the H Zone.
Describe the H Zone.
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What does the M Line represent?
What does the M Line represent?
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What is a Z disc?
What is a Z disc?
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Define sarcomere.
Define sarcomere.
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What are myofilaments?
What are myofilaments?
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What are thick filaments primarily composed of?
What are thick filaments primarily composed of?
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What are thin filaments primarily composed of?
What are thin filaments primarily composed of?
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What are intermediate (desmin) filaments?
What are intermediate (desmin) filaments?
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What is the composition of myofilaments?
What is the composition of myofilaments?
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Describe myosin's structure.
Describe myosin's structure.
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What happens during a cross bridge formation?
What happens during a cross bridge formation?
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What does actin provide in muscle cells?
What does actin provide in muscle cells?
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Define regulatory proteins in thin filaments.
Define regulatory proteins in thin filaments.
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What does the elastic filament do?
What does the elastic filament do?
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What is the function of T Tubule?
What is the function of T Tubule?
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What does the Z line signify?
What does the Z line signify?
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What is the A band?
What is the A band?
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What is the I band?
What is the I band?
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What does the sliding filament theory describe?
What does the sliding filament theory describe?
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What is the neuromuscular junction?
What is the neuromuscular junction?
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What is required for skeletal muscle fiber contraction?
What is required for skeletal muscle fiber contraction?
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What are synaptic vesicles?
What are synaptic vesicles?
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Describe the neuromuscular junction process.
Describe the neuromuscular junction process.
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What is excitation-contraction coupling?
What is excitation-contraction coupling?
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Define power stroke.
Define power stroke.
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What happens during muscle recovery?
What happens during muscle recovery?
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What is a twitch?
What is a twitch?
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What is a graded muscle response?
What is a graded muscle response?
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What is wave or temporal summation?
What is wave or temporal summation?
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Define unfused or incomplete tetanus.
Define unfused or incomplete tetanus.
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What is complete tetanus?
What is complete tetanus?
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What does treppe refer to?
What does treppe refer to?
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What is isotonic contraction?
What is isotonic contraction?
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Study Notes
Muscle Tissue Characteristics
- Excitability: Muscle tissue can respond to stimuli, primarily nervous impulses.
- Contractibility: Muscles can shorten and thicken when stimulated.
- Extensibility: Muscles have the ability to stretch beyond their normal length.
- Elasticity: Muscles can return to their original shape and size after being stretched or contracted.
Types of Muscle
- Smooth Muscle: Involuntary muscle found in the walls of hollow organs; elongated cells without striations.
- Cardiac Muscle: Striated, branched muscle with intercalated disks; it is involuntary.
- Skeletal Muscle: Long, striated muscle cells arranged in parallel; voluntary and multinucleated.
Functions of Muscle Tissue
- Movement and locomotion
- Maintaining posture
- Stabilizing joints
- Generating heat through muscle activity
Structure of Skeletal Muscle
- Composed of muscle fibers, blood vessels, nerve fibers, and connective tissue. Requires continuous oxygen and nutrient delivery.
- Direct Attachment: Epimysium of muscle fuses with the periosteum of bone or perichondrium of cartilage.
- Indirect Attachment: Tendons connect muscle to bone, extending beyond the muscle.
- Tendons: Rope-like extensions of connective tissue, while Aponeurosis is a flat sheet-like structure.
Connective Tissue Sheaths
- Epimysium: Dense connective tissue surrounding the entire muscle.
- Perimysium and Fascicles: Fascicles are bundles of muscle fibers wrapped in perimysium.
- Endomysium: Wispy connective tissue sheath surrounding individual muscle fibers.
Muscle Fiber Components
- Sarcolemma: Plasma membrane of a muscle cell.
- Sarcoplasm: Cytoplasm containing glycosomes (glycogen storage) and myoglobin (oxygen storage).
- Myofibrils: Rod-like structures that account for muscle cell volume, containing sarcomeres (contractile units) and myofilaments.
Myofilaments
- Thick Filaments: Composed of myosin, extending the entire length of the A band.
- Thin Filaments: Consists of actin, extending across the I band.
- Cross Bridge: Myosin heads link thick and thin filaments during contraction.
Sarcomere Structure
- Z Disc: Midline interruption of I band; connects thin filaments.
- H Zone: Lighter region in the A band, bisected by the M line.
- Sliding Filament Theory: Thin filaments slide over thick filaments during contraction, shortening the muscle.
Excitation-Contraction Coupling
- Action potential generation leads to muscle contraction through calcium release from the sarcoplasmic reticulum.
- Calcium binds to troponin, allowing myosin heads to attach to actin for contraction.
Muscle Contraction Types
- Twitch: Rapid, jerky response; a single contraction follows a single stimulus.
- Graded Muscle Response: Variations in muscle movement strength, influenced by stimulus frequency and intensity.
- Wave Summation: Successive stimuli cause a stronger contraction due to incomplete relaxation.
- Tetanus: Sustained muscle contraction occurs when stimuli frequency increases.
Muscle Contraction Energy Sources
- Aerobic Respiration: Generates high ATP through glycolysis and complete breakdown in mitochondria; requires continuous oxygen.
- Anaerobic Respiration: Glycolysis leads to lactic acid accumulation in the absence of oxygen; generates less ATP quickly.
- Phosphorylation: Creatine phosphate supplies phosphate to regenerate ATP quickly for short-term energy.
Muscle Fatigue and Recovery
- Fatigue: Occurs when ATP usage exceeds production, leading to lactic acid buildup and ionic imbalances.
- Recovery: Requires replenishing oxygen, converting lactic acid, resynthesizing glycogen, ATP, and creatine phosphate.
Muscle Characteristics
- Muscle Tone: Even at rest, muscles maintain slight tension to stabilize joints and posture.
- The force of muscle contractions depends on the number of crossbridges, stimulated fibers, fiber sizes, and stimulation frequency.### Muscle Physiology Basics
- Muscle contraction strength increases with the number of stimulated fibers.
- Larger muscle fibers generate stronger contractions, influenced by training and genetics.
- Muscle fiber size can be modified through exercise, though individuals are born with a predetermined number of fibers.
- Faster stimulation leads to stronger muscle contractions until optimal stretch is reached; excessive stretching hinders contraction.
- Optimal overlap of thick and thin filaments (A) ensures effective contraction, while partial overlap (B) still allows for some contraction.
Muscle Fiber Types
-
Slow Oxidative Fibers
- Contract slowly, utilize aerobic pathways for ATP production, high endurance, and rich in mitochondria.
- Resilient to fatigue but have less power due to slower ATPase activity.
-
Fast Oxidative Fibers
- Contract rapidly, also use aerobic pathways, resistant to fatigue.
- Characteristics include a rich supply of myoglobin and capillaries, allowing for quick ATP production.
-
Fast Glycolytic Fibers
- Rely on anaerobic pathways, produce less ATP quickly, and tire rapidly.
- Characterized by large diameter and minimal mitochondria; suited for brief, intense activities.
Exercise Effects on Muscle
-
Aerobic Exercise
- Increases mitochondrial numbers and myoglobin synthesis in muscle fibers.
- Primarily enhances slow oxidative fibers, contributing to endurance through angiogenesis (new capillary formation).
-
Resistance Exercise
- Focuses on anaerobic pathways and intensively loads muscles.
- More significantly increases muscle fiber size than aerobic exercise, promoting hypertrophy.
- Can convert some fast oxidative fibers to fast glycolytic fibers.
Muscle Atrophy
- Disuse atrophy occurs when muscles weaken and shrink due to inactivity.
- Prolonged disuse can lead to muscle tissue converting to fibrous connective tissue.
Smooth Muscle Structure
- Smooth muscle fibers are smaller than skeletal fibers and lack connective tissue sheaths except for the endomysium.
- Organized in layers: longitudinal for dilation and circular for constriction of tubes.
- Features no motor end plates or structured neuromuscular junctions; uses varicosities to release neurotransmitters.
Smooth Muscle Physiology
-
Peristalsis
- Smooth muscle layers contract and relax alternately, propelling contents through organ lumens.
-
Varicosities
- Enlarged nerve fibers release neurotransmitters into synaptic clefts during smooth muscle activation.
-
Sarcoplasmic Reticulum
- Lacks sarcomeres and T-tubules; instead, features caveoli for calcium concentration.
- Myofilaments consist of both thick and thin components, arranged diagonally, and lack troponin.
Smooth Muscle Contraction
- Triggered by neurotransmitter-induced action potentials that release calcium.
- Calcium interacts with calmodulin, activating myosin light chain kinase to facilitate muscle contraction.
- Involves calcium influx from both caveoli and extracellular space, leading to myosin activation and fiber shortening.
Regulation of Smooth Muscle Activity
- Controlled by autonomic nerve neurotransmitters causing excitation or inhibition.
- Influenced by chemical factors, such as oxytocin in labor and histamine during inflammation.
- Somatic motor neurons release solely acetylcholine as a neurotransmitter.
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Description
Explore key concepts from Chapter 9 of Human Anatomy and Physiology with these flashcards. Each card provides essential definitions of important terms, including excitability, contractibility, extensibility, and elasticity. Master these concepts for a deeper understanding of muscle function.