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Glomerular Filtration Rate (GFR) - lecture

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Glomerular Filtration Rate (GFR) - lecture

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Questions and Answers

What factors influence Glomerular Filtration Rate (GFR)?

Net filtration pressure and filtration coefficient (correct)

Renal blood pressure and hormonal regulation

Autoregulation and autonomic regulation

Surface area of Bowman's capsule and permeability of glomerular capillaries

What are the three levels of control for GFR?

Autoregulation, autonomic regulation, and hormonal regulation (correct)

Renal blood pressure, filtration coefficient, and surface area

Macula densa cells, afferent arterioles, and efferent arterioles

Bowman's capsule, glomerular capillaries, and tubules

How does autoregulation maintain GFR?

By changing diameters of arterioles and capillaries (correct)

By secreting ATP and adenosine

By detecting changes in salt level of fluid

By reducing blood flow into the glomerulus

What triggers dilation of afferent arterioles and capillaries?

Reduced blood flow Signup and view all the answers

What happens when renal blood pressure rises?

Afferent arterioles constrict and glomerular blood flow decreases Signup and view all the answers

What is the tubuloglomerular feedback mechanism?

A mechanism involving macula densa cells detecting changes in salt level of fluid Signup and view all the answers

What do macula densa cells secrete in response to increased salt level?

ATP and adenosine Signup and view all the answers

What is the effect of constricting the afferent arteriole?

It reduces blood flow into the glomerulus and GFR Signup and view all the answers

Which level of control for GFR occurs at the local level?

Autoregulation Signup and view all the answers

What initiates autonomic and hormonal regulation of GFR?

The kidneys Signup and view all the answers

What determines the filtration coefficient?

Surface area of glomerular capillaries available for filtration and permeability of interface between capillary and Bowman's capsule Signup and view all the answers

Study Notes

Glomerular Filtration Rate (GFR) is influenced by net filtration pressure and filtration coefficient.
Three levels of control for GFR: autoregulation, autonomic regulation, and hormonal regulation.
Autoregulation maintains GFR by changing diameters of arterioles and capillaries.
Reduced blood flow triggers dilation of afferent arterioles and capillaries, and constriction of efferent arterioles.
Rise in renal blood pressure causes constriction of afferent arterioles and decreases glomerular blood flow.
Tubuloglomerular feedback mechanism involves macula densa cells detecting changes in salt level of fluid.
Increased salt causes macula densa to secrete ATP and adenosine, which constricts smooth muscles of adjacent afferent arteriole.
Constriction of afferent arteriole reduces blood flow into the glomerulus and GFR.
Autoregulation occurs at the local level, while autonomic and hormonal regulation are initiated by the kidneys.
Filtration coefficient is determined by surface area of glomerular capillaries available for filtration and permeability of interface between capillary and Bowman's capsule.

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Description

Test your knowledge on the intricate workings of the renal system with this quiz on Glomerular Filtration Rate (GFR). From the factors that influence GFR, to the three levels of GFR control and the tubuloglomerular feedback mechanism, this quiz covers it all. Learn about autoregulation, autonomic and hormonal regulation, and how filtration coefficient is determined. Put your understanding to the test and see how well you know the complex mechanisms that govern GFR.