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Questions and Answers
Which of the following statements about chondrocytes is true?
Which of the following statements about chondrocytes is true?
- Newly divided chondrocytes do not produce the matrix material.
- They secrete metalloproteinases. (correct)
- They do not play a role in synthesizing the extracellular matrix.
- They are found only in clusters called isogenous groups.
What is the primary function of collagen in hyaline cartilage?
What is the primary function of collagen in hyaline cartilage?
- To give cartilage its shape (correct)
- To secrete metalloproteinases
- To produce the matrix material
- To provide flexibility and lubrication
What percentage of the dry weight of cartilage matrix is collagen?
What percentage of the dry weight of cartilage matrix is collagen?
- 10%-20%
- 80%-90%
- 95%-100%
- 40%-70% (correct)
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Study Notes
- Chondrocytes synthesize and maintain the extracellular matrix in hyaline cartilage.
- Chondrocytes can be found singularly or in clusters called isogenous groups.
- Isogenous groups represent recently divided cells.
- Newly divided chondrocytes produce the matrix material and secrete metalloproteinases.
- Water and inorganic salts give cartilage its flexibility and lubricating capabilities.
- Structural macromolecules in cartilage include collagens, PGs, and non-collagenous proteins.
- Type II collagen accounts for 90%-95% of the collagen in hyaline cartilage.
- Collagen provides tensile strength and shape to cartilage.
- The wet weight of cartilage is 60%-70% water and inorganic salts.
- The dry weight of cartilage matrix is 40%-70% collagen.
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