18.2

<p>MHC I and MHC II</p> Signup and view all the answers

<p>Contain antimicrobial enzymes and chemicals fuse with the phagosome to create a phagolysosome.</p> Signup and view all the answers

<p>Near the top of the molecule</p> Signup and view all the answers

<p>Dendritic cells and not macrophages to phases or B cells</p> Signup and view all the answers

<p>Internalization of pathogen by phagocytosis</p> Signup and view all the answers

<p>MHC 1 has 3 alpha protein chain coupled with a smaller beta micro globular protein and MHC 2 has 2 alpha and 2 beta protein chains the cleft for MHC 1 is made from alpha and the cleft from beta is made from beta and alpha</p> Signup and view all the answers

<p>Destroy infected cells</p> Signup and view all the answers

<p>Present antigens to MHC molecules</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>To degrade the pathogen for antigen processing</p> Signup and view all the answers

<p>To directly attack and destroy infected cells</p> Signup and view all the answers

<p>Near the 'top' (or outermost) portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>When antigens are brought into the APC by mechanisms normally leading to presentation with MHC II, but the antigen is presented on an MHC I molecule for CD8 T cells</p> Signup and view all the answers

<p>Both normal self-antigens and abnormal or nonself pathogens</p> Signup and view all the answers

<p>Only abnormal or nonself pathogen antigens</p> Signup and view all the answers

<p>They are translocated to the cell surface of the dendritic cell for presentation to T cells</p> Signup and view all the answers

<p>MHC I molecules are found on all nucleated cells while MHC II molecules are only found on macrophages, dendritic cells, and B cells.</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To fuse with the phagosome to create a phagolysosome where degradation of the pathogen for antigen processing begins</p> Signup and view all the answers

<p>The presentation of antigens on MHC I molecules for CD8 T cells</p> Signup and view all the answers

<p>Recognition and attachment of dendritic cell to a pathogen cell</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal “self” cell</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>Near the “top” (or outermost) portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>To directly attack and destroy cells infected with intracellular pathogens</p> Signup and view all the answers

<p>To present normal self-antigens as well as abnormal or nonself pathogens to the effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>They signal to the immune system that the cell is a normal 'self' cell.</p> Signup and view all the answers

<p>All nucleated cells of the body except mature red blood cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>Their structures are quite different</p> Signup and view all the answers

<p>They contain antimicrobial enzymes and chemicals</p> Signup and view all the answers

<p>The presentation of antigen on an MHC I molecule for CD8 T cells</p> Signup and view all the answers

<p>The internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>They present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>They destroy infected cells and pathogens</p> Signup and view all the answers

<p>They present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>The top portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>Signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>Their structures are quite different</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>Destroy infected cells</p> Signup and view all the answers

<p>The utilization of MHC I molecules for presentation on the cell surface</p> Signup and view all the answers

<p>Antimicrobial enzymes and chemicals</p> Signup and view all the answers

<p>Present abnormal or nonself pathogen antigens to T cells</p> Signup and view all the answers

<p>Abnormal or nonself pathogen antigens</p> Signup and view all the answers

<p>Degrade the pathogen for antigen processing</p> Signup and view all the answers

<p>Near the 'top' or outermost portion of the MHC dimer</p> Signup and view all the answers

<p>Degrade the pathogen for antigen processing</p> Signup and view all the answers

<p>All nucleated cells except mature red blood cells</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>MHC II and MHC I</p> Signup and view all the answers

<p>MHC I molecules have a cleft that serves as the antigen-binding site near the 'bottom' portion of the MHC-I dimer, while MHC II molecules have the cleft near the 'top' portion</p> Signup and view all the answers

<p>Near the 'top' portion of the MHC-II dimer</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>To directly attack and kill infected cells</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>All nucleated cells except mature red blood cells</p> Signup and view all the answers

<p>The utilization of mechanisms normally leading to presentation with MHC II, but the antigen is presented on an MHC I molecule for CD8 T cells</p> Signup and view all the answers

<p>To degrade the pathogen for antigen processing</p> Signup and view all the answers

<p>MHC I molecules are found on all nucleated cells, while MHC II molecules are only found on macrophages, dendritic cells, and B cells.</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To degrade the pathogen for antigen processing</p> Signup and view all the answers

<p>MHC I molecules</p> Signup and view all the answers

<p>MHC I and MHC II</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>To present normal self-antigens as well as abnormal or nonself pathogens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>To present normal self-antigens as well as abnormal or nonself pathogens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens to effector T cells</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>MHC I molecules are found on all nucleated cells, while MHC II molecules are only found on macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>A mechanism used by dendritic cells to present antigens on MHC I molecules</p> Signup and view all the answers

<p>To create a phagosome where degradation of the pathogen for antigen processing begins</p> Signup and view all the answers

<p>Recognition and attachment of a dendritic cell to a pathogen cell</p> Signup and view all the answers

<p>To destroy infected cells</p> Signup and view all the answers

<p>To phagocytose pathogens</p> Signup and view all the answers

<p>Mature red blood cells</p> Signup and view all the answers

<p>Near the top portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>To produce antibodies against pathogens</p> Signup and view all the answers

<p>MHC I molecules are found on all nucleated cells while MHC II molecules are only found on macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>To present abnormal or nonself pathogens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>The top portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>MHC I and MHC II</p> Signup and view all the answers

<p>To attack and destroy cells infected with intracellular pathogens</p> Signup and view all the answers

<p>To present abnormal or nonself pathogens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>All nucleated cells except mature red blood cells</p> Signup and view all the answers

<p>MHC I molecules have a cleft that serves as the antigen-binding site near the 'top' (or outermost) portion of the molecule while MHC II molecules have a cleft that serves as the antigen-binding site near the 'bottom' (or innermost) portion of the molecule</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>MHC I molecules present abnormal or nonself pathogen antigens for the initial activation of T cells, while MHC II molecules present normal self-antigens.</p> Signup and view all the answers

<p>To contain antimicrobial enzymes and chemicals for degradation of the pathogen for antigen processing</p> Signup and view all the answers

<p>The utilization of MHC I molecules to present antigens brought into the APC by mechanisms normally leading to presentation with MHC II</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>To release cytokines and perform cytotoxic functions against infected cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>The top portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>Dendritic cells</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>All nucleated cells of the body</p> Signup and view all the answers

<p>To present abnormal or nonself pathogens to effector T cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>MHC I molecules have a cleft that serves as the antigen-binding site near the 'bottom' portion of the molecule, while MHC II molecules have it near the 'top' portion</p> Signup and view all the answers

<p>The presentation of antigens on MHC I molecules by dendritic cells</p> Signup and view all the answers

<p>Only dendritic cells</p> Signup and view all the answers

<p>To present self-antigens to effector T cells</p> Signup and view all the answers

<p>To present abnormal or nonself pathogens to effector T cells</p> Signup and view all the answers

<p>Internalization of a pathogen by phagocytosis</p> Signup and view all the answers

<p>To degrade pathogens for antigen processing</p> Signup and view all the answers

<p>Abnormal or nonself pathogen antigens</p> Signup and view all the answers

<p>Abnormal or nonself pathogen antigens</p> Signup and view all the answers

<p>To directly attack and destroy infected cells</p> Signup and view all the answers

<p>Signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>Present abnormal or nonself pathogen antigens for initial activation of T cells</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>MHC II molecules have a cleft that serves as the antigen-binding site near the 'top' portion of the molecule, while MHC I molecules do not have a cleft</p> Signup and view all the answers

<p>Cross-presentation</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>Contain antimicrobial enzymes and chemicals for degradation of the pathogen</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>Near the 'top' portion of the molecule</p> Signup and view all the answers

<p>Destroy infected cells bearing abnormal MHC I molecules</p> Signup and view all the answers

<p>To present both normal self-antigens and abnormal/nonself pathogens</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>MHC II molecules are transmembrane glycoproteins, while MHC I molecules are not</p> Signup and view all the answers

<p>The pathogen is internalized by phagocytosis</p> Signup and view all the answers

<p>To recognize and kill infected cells</p> Signup and view all the answers

<p>To present antigens to MHC molecules</p> Signup and view all the answers

<p>To fuse with the phagosome and create a phagolysosome for antigen processing</p> Signup and view all the answers

<p>Presentation of antigens on MHC I molecules</p> Signup and view all the answers

<p>Near the top (or outermost) portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>To present normal self-antigens only</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>To produce antibodies against pathogens</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>MHC I molecules present abnormal or nonself pathogens to effector T cells involved in cellular immunity, while MHC II molecules present normal self-antigens</p> Signup and view all the answers

<p>The presentation of antigens on an MHC I molecule for CD8 T cells when the intracellular pathogen does not directly infect antigen-presenting cells</p> Signup and view all the answers

<p>They are found on all cells except red blood cells</p> Signup and view all the answers

<p>They present abnormal or nonself pathogens to effector T cells involved in cellular immunity</p> Signup and view all the answers

<p>They present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>MHC molecules have a cleft that serves as the antigen-binding site near the outermost portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>To contain antimicrobial enzymes and chemicals that fuse with the phagosome</p> Signup and view all the answers

<p>A mechanism by which antigens are presented on MHC I molecules for CD8 T cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>They are translocated to the cell surface of dendritic cells for presentation to T cells</p> Signup and view all the answers

<p>To present normal self-antigens only</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>To eliminate infected cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>Present normal self-antigens to T cells</p> Signup and view all the answers

<p>Present antigens to T cells</p> Signup and view all the answers

<p>MHC II molecules have a cleft that serves as the antigen-binding site</p> Signup and view all the answers

<p>The pathogen is internalized by phagocytosis and is initially contained within a phagosome</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>Kill infected cells</p> Signup and view all the answers

<p>Degrade the pathogen for antigen processing</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>MHC I and MHC II</p> Signup and view all the answers

<p>Present abnormal or nonself pathogen antigens to T cells</p> Signup and view all the answers

<p>The top portion of the MHC dimer</p> Signup and view all the answers

<p>Signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>Present abnormal or nonself pathogen antigens for initial activation of T cells</p> Signup and view all the answers

<p>Both are transmembrane glycoproteins that assemble as dimers in the cytoplasmic membrane of cells, but their structures are quite different</p> Signup and view all the answers

<p>Phagocytosis</p> Signup and view all the answers

<p>Dendritic cells</p> Signup and view all the answers

<p>Near the 'top' portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>Destroy infected cells</p> Signup and view all the answers

<p>Present abnormal or nonself pathogen antigens for initial activation of T cells</p> Signup and view all the answers

<p>Degrade the pathogen for antigen processing</p> Signup and view all the answers

<p>MHC I and MHC II</p> Signup and view all the answers

<p>All nucleated cells</p> Signup and view all the answers

<p>To present both normal self-antigens and abnormal or nonself pathogens</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>MHC I molecules are found on all nucleated cells, while MHC II molecules are found only on macrophages</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>Near the 'top' or outermost portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>Antigens are brought into the APC by mechanisms normally leading to presentation with MHC II, but the antigen is presented on an MHC I molecule for CD8 T cells</p> Signup and view all the answers

<p>To create a phagolysosome where degradation of the pathogen for antigen processing begins</p> Signup and view all the answers

<p>Only dendritic cells</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>To directly attack and destroy infected cells</p> Signup and view all the answers

<p>To present both normal self-antigens and abnormal or nonself pathogens</p> Signup and view all the answers

<p>MHC I and MHC II molecules have different structures</p> Signup and view all the answers

<p>To present both normal self-antigens and abnormal or nonself pathogens</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>MHC I molecules are found on all nucleated cells, while MHC II molecules are only found on macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>To degrade pathogens for antigen processing</p> Signup and view all the answers

<p>When antigens are brought into the APC by mechanisms normally leading to presentation with MHC II, but the antigen is presented on an MHC I molecule for CD8 T cells</p> Signup and view all the answers

<p>To signal to the immune system that the cell is a normal 'self' cell</p> Signup and view all the answers

<p>Both MHC I and MHC II molecules are transmembrane glycoproteins that assemble as dimers in the cytoplasmic membrane of cells, but their structures are quite different</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>When antigens are brought into the APC by mechanisms normally leading to presentation with MHC I, but the antigen is presented on an MHC II molecule for CD4 T cells</p> Signup and view all the answers

<p>Red blood cells</p> Signup and view all the answers

<p>To directly attack and kill infected cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>MHC I molecules present abnormal or nonself pathogens to effector T cells, while MHC II molecules present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>To present antigens on MHC I molecules for CD8 T cells</p> Signup and view all the answers

<p>Internalization of the pathogen by phagocytosis</p> Signup and view all the answers

<p>To create a phagolysosome where degradation of the pathogen for antigen processing begins</p> Signup and view all the answers

<p>That the cell is a normal 'self' cell</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>Macrophages, dendritic cells, and B cells</p> Signup and view all the answers

<p>Near the 'top' (or outermost) portion of the MHC-I or MHC-II dimer</p> Signup and view all the answers

<p>To directly attack and destroy infected cells</p> Signup and view all the answers

<p>To present abnormal or nonself pathogen antigens for the initial activation of T cells</p> Signup and view all the answers

<p>To present normal self-antigens to effector T cells</p> Signup and view all the answers