Peptide Presentation by Class II MHC Molecules
7 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which type of cells are responsible for internalizing antigens in the class II MHC pathway?

  • B lymphocytes
  • Dendritic cells (correct)
  • T lymphocytes
  • Macrophages
  • What happens to the antigens after internalization into APCs?

  • They bind to class II MHC molecules
  • They are broken down by proteolytic enzymes (correct)
  • They are transported to the cell surface
  • They enter acidic intracellular vesicles
  • Where do peptides bind to newly synthesized class II MHC molecules?

  • In the endosomes or phagosomes
  • In the ER (correct)
  • In the extracellular environment
  • In the lysosomes
  • Which protein is attached to the newly synthesized class II molecule?

    <p>Invariant chain (Ii)</p> Signup and view all the answers

    Where does the newly synthesized class II molecule with its associated Ii migrate to?

    <p>Endosomes and lysosomes</p> Signup and view all the answers

    What is the function of the class II MHC–like protein called DM?

    <p>To exchange CLIP in the class II MHC molecule with other peptides</p> Signup and view all the answers

    What happens to class II molecules that do not find peptides they can bind?

    <p>They are degraded by lysosomal proteases</p> Signup and view all the answers

    More Like This

    MHC Molecules
    6 questions

    MHC Molecules

    StupendousNovaculite avatar
    StupendousNovaculite
    MHC Flashcards
    24 questions

    MHC Flashcards

    ChivalrousSard7112 avatar
    ChivalrousSard7112
    MHC Class I vs Class II Overview
    9 questions
    Use Quizgecko on...
    Browser
    Browser