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Questions and Answers
Which type of cells are responsible for internalizing antigens in the class II MHC pathway?
Which type of cells are responsible for internalizing antigens in the class II MHC pathway?
- B lymphocytes
- Dendritic cells (correct)
- T lymphocytes
- Macrophages
What happens to the antigens after internalization into APCs?
What happens to the antigens after internalization into APCs?
- They bind to class II MHC molecules
- They are broken down by proteolytic enzymes (correct)
- They are transported to the cell surface
- They enter acidic intracellular vesicles
Where do peptides bind to newly synthesized class II MHC molecules?
Where do peptides bind to newly synthesized class II MHC molecules?
- In the endosomes or phagosomes
- In the ER (correct)
- In the extracellular environment
- In the lysosomes
Which protein is attached to the newly synthesized class II molecule?
Which protein is attached to the newly synthesized class II molecule?
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Where does the newly synthesized class II molecule with its associated Ii migrate to?
Where does the newly synthesized class II molecule with its associated Ii migrate to?
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What is the function of the class II MHC–like protein called DM?
What is the function of the class II MHC–like protein called DM?
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What happens to class II molecules that do not find peptides they can bind?
What happens to class II molecules that do not find peptides they can bind?
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