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Questions and Answers
What is the most common cause of thyrotoxicosis in pregnancy?
What is the most common cause of thyrotoxicosis in pregnancy?
- Hashimoto's disease
- Thyroid cancer
- Graves' disease (correct)
- Hypothyroidism
What should be checked at 30-36 weeks gestation?
What should be checked at 30-36 weeks gestation?
- Blood glucose levels
- Cholesterol levels
- Thyrotrophin receptor stimulating antibodies (correct)
- Blood pressure
What is the recommended medication for treating thyrotoxicosis in the first trimester of pregnancy?
What is the recommended medication for treating thyrotoxicosis in the first trimester of pregnancy?
- Carbimazole
- Liothyronine
- Propylthiouracil (correct)
- Levothyroxine
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Study Notes
- Pregnancy causes an increase in total thyroxine levels but not free thyroxine levels
- Untreated thyrotoxicosis in pregnancy increases the risk of fetal loss, maternal heart failure, and premature labor
- Graves' disease is the most common cause of thyrotoxicosis in pregnancy
- Propylthiouracil is used in the first trimester of pregnancy instead of carbimazole
- Maternal free thyroxine levels should be kept in the upper third of the normal reference range
- Thyrotrophin receptor stimulating antibodies should be checked at 30-36 weeks gestation
- Block-and-replace regimes should not be used in pregnancy
- Radioiodine therapy is contraindicated in pregnancy
- Women require an increased dose of thyroxine during pregnancy
- Breastfeeding is safe while on thyroxine
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