6 Questions
What is the most common cause of thyrotoxicosis during pregnancy?
Graves' disease
Which of the following can cause Pseudo-Cushing's syndrome?
Chronic illness
Which medication is preferred in the first trimester of pregnancy for the treatment of thyrotoxicosis?
Propylthiouracil
What test can differentiate between true Cushing's and Pseudo-Cushing's?
Dexamethasone suppression test
What is the recommended range for free thyroxine levels during pregnancy?
Upper third of the normal reference range
Why is ITT not a first-line diagnostic test?
It has potential risks
Study Notes
- Pregnancy increases levels of thyroxine-binding globulin (TBG)
- Graves' disease is the most common cause of thyrotoxicosis in pregnancy
- Untreated thyrotoxicosis increases the risk of fetal loss, maternal heart failure, and premature labor
- Propylthiouracil is used in the first trimester of pregnancy instead of carbimazole
- Free thyroxine levels should be kept in the upper third of the normal reference range
- Thyrotrophin receptor stimulating antibodies should be checked at 30-36 weeks gestation
- Block-and-replace regimes should not be used in pregnancy
- Radioiodine therapy is contraindicated
- Thyroxine is safe during pregnancy
- Women require an increased dose of thyroxine during pregnancy by up to 50% as early as 4-6 weeks of pregnancy
Test your knowledge on the important topic of thyroid disorders in pregnancy with this informative quiz. From the effects of pregnancy on thyroxine-binding globulin levels to the use of propylthiouracil over carbimazole, this quiz covers key concepts that every healthcare professional should know. Take the quiz to learn about the potential risks of untreated thyrotoxicosis, the importance of checking thyrotrophin receptor stimulating antibodies, and why block-and-replace regimes should be avoided during pregnancy.
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