Hormones and Carbohydrate Metabolism

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Questions and Answers

What is the primary effect of glucagon on glycogen metabolism?

  • No effect on glycogen metabolism
  • Increases glycogen synthesis
  • Increases glycogen breakdown (correct)
  • Decreases glycogen breakdown

Which hormone has the primary target of muscle tissue?

  • Glucagon
  • Epinephrine
  • Insulin (correct)
  • None of the above

How does insulin affect the level of Fructose-2,6-bisphosphate in muscle tissue?

  • Increases only in liver tissue
  • No effect on the level
  • Decreases the level
  • Increases the level (correct)

Which hormone primarily increases cyclic-AMP levels in the body?

<p>Both glucagon and epinephrine (B)</p> Signup and view all the answers

What is the effect of epinephrine on gluconeogenesis?

<p>Promotes gluconeogenesis (D)</p> Signup and view all the answers

Flashcards

Glucagon's effect on cyclic-AMP

Glucagon increases cyclic-AMP levels in the liver, stimulating processes like gluconeogenesis (new sugar synthesis) and glycogen breakdown.

Glucagon's effect on Fructose-2,6-bisphosphate

Glucagon increases Fructose-2,6-bisphosphate levels in the liver to further encourage gluconeogenesis and glycogen breakdown

Epinephrine's effect on gluconeogenesis

Epinephrine increases gluconeogenesis in muscle and liver, primarily targeting the muscle first.

Insulin's effect on cyclic-AMP

Insulin decreases cyclic-AMP levels in muscle, liver, and adipose tissues.

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Insulin's effect on Fructose-2,6-bisphosphate

Insulin decreases Fructose-2,6-bisphosphate levels in muscle; and insulin does not inhibit F-2,6-BP change in other tissues (liver or adipose).

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Source of Glucagon

Glucagon is produced by alpha cells in the pancreas.

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Source of Epinephrine

Epinephrine is produced by the adrenal medulla.

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Source of Insulin

Insulin is produced by beta cells in the pancreas.

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Primary target of Glucagon

The liver is the primary target of glucagon in carbohydrate metabolism.

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Primary target of Epinephrine

Muscle is the primary target of epinephrine, although liver is also affected.

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Primary target of Insulin

Insulin primarily targets muscle, liver, and adipose tissues in carbohydrate metabolism

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Study Notes

Effects of Hormones on Carbohydrate Metabolism

  • Hormones: Glucagon, Epinephrine, Insulin
  • Source of Hormones:
    • Glucagon: Pancreatic α cells
    • Epinephrine: Adrenal medulla
    • Insulin: Pancreatic β cells
  • Primary Targets:
    • Glucagon: Liver
    • Epinephrine: Muscle > Liver
    • Insulin: Muscle, liver, adipose tissue
  • Effects on Metabolic Processes:
    • Cyclic AMP: Increased by Glucagon and Epinephrine
    • Fructose-2,6-bisphosphate: Decreased by Glucagon and Epinephrine
    • Gluconeogenesis: Increased by Glucagon and Epinephrine
    • Glycogen Breakdown: Increased by Glucagon and Epinephrine, decreased by Insulin
  • Specific actions in muscle: Epinephrine increases glycogen breakdown in muscle, Insulin decreases glycogen breakdown in muscle.

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