Hormone Actions and Regulation
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Questions and Answers

What will an injection of epinephrine do?

Bronchodilation of airways, increase your heart rate, decrease your digestive functions.

What part of the pituitary gland has a connection with the neurons of the hypothalamus?

Posterior pituitary

Which chemical type of hormone has a longer half-life?

Steroid hormone, lipid soluble

Why is ADH also called vasopressin? Due to high concentration, what type of action?

<p>Increase blood pressure by constriction of blood vessels.</p> Signup and view all the answers

Which hormone from the anterior pituitary regulates thyroid hormone levels?

<p>TSH</p> Signup and view all the answers

What 3 things can regulate hormonal secretion?

<p>Hormone, substances, nervous system</p> Signup and view all the answers

Name a hormone that is made from cholesterol?

<p>Steroid hormones</p> Signup and view all the answers

The connecting stalk between the pituitary and hypothalamus is called?

<p>Infundibulum</p> Signup and view all the answers

What type of chemical messenger will act on nearby cells?

<p>Paracrine</p> Signup and view all the answers

What hormone would decrease if you had increased plasma levels of cortisol?

<p>ACTH</p> Signup and view all the answers

T3 and T4 are stored in the parafollicular as which molecule?

<p>Thyroglobulin</p> Signup and view all the answers

You have a distance runner that twisted their ankle but continued the run, what was the hormone secreted to subdue the perception of pain?

<p>Beta Endorphins</p> Signup and view all the answers

What hormone would inhibit the secretion of growth hormone?

<p>GHIH Growth hormone inhibiting hormone</p> Signup and view all the answers

What can stimulate oxytocin release?

<p>Suckling of the breast and contraction of uterus</p> Signup and view all the answers

If there is a decrease in blood volume that would be released in what type of situation?

<p>Low blood pressure, urine output</p> Signup and view all the answers

What role does oxytocin play in lactation?

<p>Ejection of milk</p> Signup and view all the answers

Which hormone is secreted in response to increased osmotic pressure of the body fluids?

<p>ADH</p> Signup and view all the answers

Which structure carries neurons from the hypothalamus to the posterior pituitary?

<p>Hypothalamic-hypophyseal tract</p> Signup and view all the answers

Hormones from which structure controls the secretion of the anterior pituitary?

<p>Neurohormones of the Hypothalamus</p> Signup and view all the answers

From where to where does the hypothalamo-hypophyseal carry hormones?

<p>Hypothalamus to the pituitary</p> Signup and view all the answers

What are the 2 functions of the pituitary gland?

<p>Neurohypophysis, adenohypophysis</p> Signup and view all the answers

What structure regulates the secretary of the pituitary gland?

<p>Hypothalamus</p> Signup and view all the answers

What deficiency does your patient have if the patient is feeling tired lately after having blood work completed showing elevated TSH, low iodine, low thyroid hormone levels?

<p>Lack of iodine</p> Signup and view all the answers

After a meal, blood glucose levels rise and stimulate the release of insulin, what type of stimulation is this an example of?

<p>Humoral stimulus</p> Signup and view all the answers

Which kind of hormones diffuse easily through the plasma membrane?

<p>Hydrophobic Ex: Steroid hormone</p> Signup and view all the answers

Where are the receptors for the most lipid soluble hormones located?

<p>Nucleus or the Cytoplasm of the target cells</p> Signup and view all the answers

Where are the receptors for most soluble hormones located?

<p>Plasma membrane of target cells</p> Signup and view all the answers

What process produces an increase in the sensitivity of the target cell to the hormone?

<p>Up-regulation</p> Signup and view all the answers

By what mechanism are most hormones regulated?

<p>Negative feedback</p> Signup and view all the answers

In some forms of diabetes an insensitivity to insulin seems to be present, what does this insensitivity seem to be the result of?

<p>Down regulation</p> Signup and view all the answers

Parathyroid hormone is released when blood calcium is released, this is an example controlled by which stimuli?

<p>Humoral stimuli</p> Signup and view all the answers

Lipid soluble hormones can be more easily excreted once they have water soluble molecules added to their structure. This is called?

<p>Conjugation</p> Signup and view all the answers

What term do we use for an intercellular chemical signal that is produced by neurons but functions like a hormone?

<p>Neurohormone</p> Signup and view all the answers

What do all hormones have in common?

<p>Chemical signals that attach to receptors on the target cell</p> Signup and view all the answers

What is the main hormone of the male reproductive system?

<p>Testosterone</p> Signup and view all the answers

What would adrenal androgens do in females?

<p>Pubic Hair, hypertrophy of the clitoris, precocious puberty</p> Signup and view all the answers

Which hormone stimulates development of follicles in the ovary?

<p>Follicle stimulating hormone, FSH</p> Signup and view all the answers

What condition does the patient have if they have no height increase, large hands and large tongue?

<p>Acromegaly</p> Signup and view all the answers

If you compare the nervous and endocrine system which one responds quickly and stays active?

<p>Endocrine stays longer</p> Signup and view all the answers

What happens to hormones with short half-life?

<p>Leave body faster</p> Signup and view all the answers

If a patient with insulin dependent diabetes mellitus forgets to take their insulin, what would that cause?

<p>Hyperglycemia</p> Signup and view all the answers

What would increase insulin secretion immediately following their meal?

<p>Elevated Blood Glucose</p> Signup and view all the answers

Which cells does glucagon primarily influence?

<p>Cells of the liver</p> Signup and view all the answers

2 hormones increase and decrease when blood sugar levels decrease. What are those hormones?

<p>Insulin and Glucagon</p> Signup and view all the answers

Which hormones are produced in the islets of Langerhans?

<p>Insulin, glucagon</p> Signup and view all the answers

Which cells of the pancreas secrete glucagon?

<p>Alpha Cells</p> Signup and view all the answers

High blood glucose levels increase which secretion of which hormone?

<p>Insulin</p> Signup and view all the answers

What condition may be the cause of hypoglycemia, depressed immune system and redistribution of fat from limbs to the face limbs and abdomen?

<p>Cushing's syndrome</p> Signup and view all the answers

Which organ has both an endocrine and exocrine function?

<p>Pancreas</p> Signup and view all the answers

Which hormone has the function of increasing the uptake of glucose by the target cells?

<p>Insulin</p> Signup and view all the answers

Which hormone stimulates gluconeogenesis?

<p>Glucocorticoid</p> Signup and view all the answers

Which hormone is secreted by the zona fascicular by the adrenal gland?

<p>Cortisol</p> Signup and view all the answers

The primary stimulus for the release of adrenal medullary hormones comes from where?

<p>Sympathetic nervous system</p> Signup and view all the answers

What 3 hormones are secreted by the adrenal cortex?

<p>Aldosterone, cortisol, androgens</p> Signup and view all the answers

What hormone if injected increases blood pressure?

<p>Epinephrine</p> Signup and view all the answers

Which endocrine gland are located on top of the kidneys?

<p>Adrenal Glands</p> Signup and view all the answers

What are the major secreting project of the zona glomerulosa of the adrenal cortex?

<p>Aldosterone, mineralocorticoids</p> Signup and view all the answers

When does the rate of secretion of parathyroid hormone increase?

<p>Parathyroid hormone increases blood calcium levels, Blood calcium level is too low</p> Signup and view all the answers

When does patient complain of weight gain?

<p>Hypothyroidism</p> Signup and view all the answers

Your patient shows they have increased metabolic activity and weight loss what condition do they have?

<p>Hyperthyroidism</p> Signup and view all the answers

What ion is necessary for production?

<p>Iodine</p> Signup and view all the answers

If your patient presents with exophthalmos, what hormone is secreted in larger quantities?

<p>Thyroid hormone</p> Signup and view all the answers

What hormone is required for ovulation and formation of the corpus gluten?

<p>Luteinizing hormone</p> Signup and view all the answers

If there is hypersecretion of growth hormone in a child what is the condition?

<p>Gigantism</p> Signup and view all the answers

What hormone increase amino acid up-take?

<p>Growth hormone</p> Signup and view all the answers

What gland is located in the Sella Turcica?

<p>Pituitary gland / Hypophysis</p> Signup and view all the answers

Which hormone is stored and released in the posterior pituitary?

<p>ADH and Oxytocin</p> Signup and view all the answers

What happens to urine volume when urine volume decreases?

<p>Concentration Increases</p> Signup and view all the answers

Which hormone would be affected if fluid intake increases dramatically over a short time frame?

<p>Atrial Natriuretic Peptide</p> Signup and view all the answers

Which hormones are synthesized by the hypothalamus?

<p>all of the inhibiting and releasing hormones / oxytocin/ ADH</p> Signup and view all the answers

What hormone is sometimes given to women to induce labor?

<p>Oxytocin</p> Signup and view all the answers

What is the role of cyclic AMP when it acts as an intracellular mediator?

<p>Activates protein kinase</p> Signup and view all the answers

What is the regulatory protein associated with membrane bound receptor molecules, it has 3 subunits?

<p>G protein</p> Signup and view all the answers

What type of chemical messenger stimulates the cell that originally secreted it?

<p>Autocrine</p> Signup and view all the answers

Flashcards

Epinephrine effects

Increases heart rate, bronchodilation, decreases digestive functions.

Posterior pituitary

Part of the pituitary connected to hypothalamus' neurons.

Steroid hormones

Hormones that are lipid soluble and have a longer half-life.

ADH

Also called vasopressin; increases blood pressure via blood vessel constriction.

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TSH

Hormone from anterior pituitary that regulates thyroid hormone levels.

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Hormonal secretion regulation

Regulated by hormones, substances, and nervous system.

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Infundibulum

Stalk connecting pituitary and hypothalamus.

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Paracrine

Chemical messenger acting on nearby cells.

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Cortisol effect

Increased plasma cortisol levels decrease ACTH.

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Thyroglobulin

Storage form for T3 and T4 in the thyroid.

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Beta Endorphins

Hormones that subdue pain perception during stress.

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GHIH

Growth hormone inhibiting hormone; inhibits GH secretion.

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Oxytocin release

Stimulated by suckling and uterine contractions.

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Low blood pressure response

ADH and other hormones are released when blood volume decreases.

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Oxytocin role in lactation

Ejects milk from the mammary glands.

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Neurohormones

Control anterior pituitary secretion from the hypothalamus.

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Up-regulation

Increase in target cell sensitivity to a hormone.

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Negative feedback

Main mechanism regulating most hormones.

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Insulin function

Increases glucose uptake by target cells.

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Glucagon influence

Primarily influences liver cells to release glucose.

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Cushing's syndrome effects

Causes hypoglycemia, depressed immune system, fat redistribution.

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Pancreas function

Organ with both endocrine and exocrine functions.

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Testosterone

Main hormone of the male reproductive system.

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FSH

Follicle-stimulating hormone that promotes ovarian follicle development.

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ADH and Oxytocin storage

Hormones stored and released from the posterior pituitary.

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Growth hormone effects

Increases amino acid uptake and can cause gigantism when overproduced.

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ANP

Atrial natriuretic peptide; decreases fluid retention.

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Cyclic AMP role

Acts as an intracellular mediator to activate protein kinases.

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G protein

Regulatory protein associated with membrane-bound receptor molecules.

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Autocrine

Chemical messenger stimulating the original secreting cell.

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Zona glomerulosa

Secretes aldosterone and mineralocorticoids.

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Hyperthyroidism

Condition characterized by increased metabolic activity and weight loss.

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Hypothyroidism

Condition causing weight gain due to decreased metabolic activity.

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Study Notes

Hormone Actions and Regulation

  • Epinephrine causes bronchodilation, increased heart rate, and decreased digestive function.
  • The posterior pituitary is connected to the hypothalamus's neurons.
  • Lipid-soluble hormones (steroid hormones) have longer half-lives.
  • Antidiuretic hormone (ADH) is also called vasopressin, increasing blood pressure by constricting blood vessels.
  • Thyroid-stimulating hormone (TSH) from the anterior pituitary controls thyroid hormone levels.
  • Hormone secretion is regulated by hormones, substances, and the nervous system.
  • Growth hormone is made from cholesterol.
  • The infundibulum connects the pituitary and hypothalamus.
  • Paracrine messengers act on nearby cells.
  • Adrenocorticotropic hormone (ACTH) decreases if cortisol levels are high.
  • Thyroglobulin is the molecule where T3 and T4 are stored in parafollicular cells.
  • Beta-endorphins are secreted to reduce pain perception in injury cases.
  • Growth hormone-inhibiting hormone (GHIH) inhibits growth hormone secretion.
  • Oxytocin release is stimulated by breastfeeding and uterine contractions.
  • Low blood pressure and decreased urine output trigger the release of hormones in response to decreased blood volume.
  • Oxytocin causes milk ejection during lactation.

Pituitary Gland and Function

  • Antidiuretic hormone (ADH) is released in response to increased body fluid osmotic pressure.
  • The hypothalamic-hypophyseal tract carries neurons from the hypothalamus to the posterior pituitary.
  • Neurohormones from the hypothalamus regulate the anterior pituitary's secretion.
  • Hormones travel from the hypothalamus to the pituitary via the hypothalamo-hypophyseal tract.
  • The pituitary gland has two functions: neurohypophysis and adenohypophysis.
  • The hypothalamus controls pituitary secretion.
  • Iodine deficiency causes low thyroid hormone levels and fatigue.
  • Humoral stimulation is triggered by changes in blood glucose levels, leading to insulin release.
  • Steroid hormones easily pass through the plasma membrane.
  • Receptors for lipid-soluble hormones are in the nucleus or cytoplasm of target cells.
  • Receptors for water-soluble hormones are on the plasma membrane.
  • Increased target cell sensitivity to hormones is called up-regulation.
  • Hormone regulation commonly occurs through negative feedback loops.
  • Insulin insensitivity can result from downregulation in some cases of diabetes.

Various Hormonal Functions

  • Parathyroid hormone regulates calcium levels.
  • Hormones are transported easily after water-soluble molecules are conjugated.
  • Neurohormones are chemical signals produced by neurons with hormonal function.
  • Testosterone is the primary male reproductive hormone.
  • Follicle-stimulating hormone (FSH) stimulates follicle development in the ovaries.
  • Large hands and tongue, and lack of height increase indicate Hepatomegaly
  • Short-lived hormones leave the body quickly.
  • Insulin deficiency can cause hyperglycemia .
  • Glucagon primarily affects liver cells.
  • Glucagon and insulin have opposing roles in blood sugar regulation.
  • Alpha cells in the pancreas secrete glucagon.
  • Cushing's syndrome is characterized by high blood glucose, depressed immunity, and fat redistribution.
  • The pancreas has both endocrine and exocrine functions.
  • Insulin increases glucose uptake into target cells.
  • Glucocorticoids, like cortisol, stimulate gluconeogenesis.
  • The sympathetic nervous system triggers adrenal medullary hormone release.
  • The adrenal cortex secretes three hormones: aldosterone, cortisol, and androgens.
  • Epinephrine increases blood pressure.
  • Adrenal glands are located atop the kidneys.
  • Aldosterone is produced in the zona glomerulosa of the adrenal cortex.
  • Parathyroid hormone increases when blood calcium is low.
  • Hypothyroidism causes weight gain.

Hormonal Regulation & Effects

  • Increased metabolic rate and weight loss indicate hyperthyroidism.
  • Iodine is needed for thyroid hormone production.
  • Thyroid hormone is crucial for ovulation and corpus luteum formation
  • Gigantism results from excessive growth hormone in children.
  • Growth hormone increases amino acid uptake.
  • ADH and oxytocin are stored and released in the posterior pituitary.
  • ANP decreases when fluid intake rapidly increases.
  • Oxytocin is sometimes used to induce labor.
  • Cyclic AMP activates protein kinase.
  • G protein is a regulatory protein associated with membrane receptors.
  • Autocrine signaling involves a hormone stimulating the cell that secreted it.

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Description

This quiz covers the roles and mechanisms of various hormones in the human body. Questions will explore topics such as hormone secretion, regulation, and specific functions of key hormones like epinephrine, ADH, and TSH. Test your knowledge on how hormones influence physiological processes.

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