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Questions and Answers
What is the main difference between non-targeted drug discovery and targeted drug discovery?
What is the main difference between non-targeted drug discovery and targeted drug discovery?
- Non-targeted drug discovery involves finding natural products, while targeted drug discovery involves synthetically making chemical variants.
- Non-targeted drug discovery involves finding a new use for an existing drug, while targeted drug discovery involves drug repurposing.
- Non-targeted drug discovery involves identifying a specific disease target, while targeted drug discovery involves screening for compounds that affect a specific target. (correct)
- Non-targeted drug discovery involves identifying a specific disease target, while targeted drug discovery involves finding a new use for an existing drug.
What is the primary goal of drug development?
What is the primary goal of drug development?
- To find a lead compound with potential therapeutic effects
- To test a compound's safety and efficacy in humans (correct)
- To synthetically make chemical variants of a natural product
- To identify a specific disease target for drug development
Which of the following is an example of non-targeted drug discovery?
Which of the following is an example of non-targeted drug discovery?
- Designing a compound to target a specific receptor
- Identifying a new disease target for an existing drug
- Screening a library of compounds for activity against a specific disease
- Discovering penicillin from a natural source (correct)
What is the primary goal of drug repurposing?
What is the primary goal of drug repurposing?
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What is the difference between drug discovery and drug development?
What is the difference between drug discovery and drug development?
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Which of the following is an example of chemistry-driven drug discovery?
Which of the following is an example of chemistry-driven drug discovery?
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What is the main advantage of non-targeted drug discovery?
What is the main advantage of non-targeted drug discovery?
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What is the primary goal of natural product drug discovery?
What is the primary goal of natural product drug discovery?
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Study Notes
Non-Targeted Drug Discovery
- There are three major types of non-targeted drug discovery:
- Natural product drug discovery: finding natural products
- Chemistry-driven drug discovery: synthetically making chemical variants
- Drug repurposing/repositioning: finding a new use for an existing drug
Non-Targeted vs Targeted Drug Discovery
- Non-targeted drug discovery can occur alongside targeted drug discovery
- Non-targeted drug discovery is the focus for this topic
Examples of Non-Targeted Drug Discovery
- Penicillin: an example of non-targeted drug discovery
- Nitrogen mustard chemotherapy drugs: also an example of non-targeted drug discovery
Important Tasks
- Read the article 'Maker of the Miracle Mould' to understand more about non-targeted drug discovery
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