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HMM304: Therapeutic Development - Week 1, Class 3

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HMM304: Therapeutic Development - Week 1, Class 3

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Questions and Answers

What is the main difference between non-targeted drug discovery and targeted drug discovery?

Non-targeted drug discovery involves finding natural products, while targeted drug discovery involves synthetically making chemical variants.

Non-targeted drug discovery involves finding a new use for an existing drug, while targeted drug discovery involves drug repurposing.

Non-targeted drug discovery involves identifying a specific disease target, while targeted drug discovery involves screening for compounds that affect a specific target. (correct)

Non-targeted drug discovery involves identifying a specific disease target, while targeted drug discovery involves finding a new use for an existing drug.

What is the primary goal of drug development?

To find a lead compound with potential therapeutic effects

To test a compound's safety and efficacy in humans (correct)

To synthetically make chemical variants of a natural product

To identify a specific disease target for drug development

Which of the following is an example of non-targeted drug discovery?

Designing a compound to target a specific receptor

Identifying a new disease target for an existing drug

Screening a library of compounds for activity against a specific disease

Discovering penicillin from a natural source (correct)

What is the primary goal of drug repurposing?

To find a new use for an existing drug (C) Signup and view all the answers

What is the difference between drug discovery and drug development?

Drug discovery involves finding a lead compound, while drug development involves testing its safety and efficacy (D) Signup and view all the answers

Which of the following is an example of chemistry-driven drug discovery?

Synthetically making chemical variants of a natural product (B) Signup and view all the answers

What is the main advantage of non-targeted drug discovery?

It increases the chances of finding a lead compound with potential therapeutic effects (D) Signup and view all the answers

What is the primary goal of natural product drug discovery?

To find a lead compound with potential therapeutic effects (D) Signup and view all the answers

Study Notes

Non-Targeted Drug Discovery

There are three major types of non-targeted drug discovery:
- Natural product drug discovery: finding natural products
- Chemistry-driven drug discovery: synthetically making chemical variants
- Drug repurposing/repositioning: finding a new use for an existing drug

Non-Targeted vs Targeted Drug Discovery

Non-targeted drug discovery can occur alongside targeted drug discovery
Non-targeted drug discovery is the focus for this topic

Examples of Non-Targeted Drug Discovery

Penicillin: an example of non-targeted drug discovery
Nitrogen mustard chemotherapy drugs: also an example of non-targeted drug discovery

Important Tasks

Read the article 'Maker of the Miracle Mould' to understand more about non-targeted drug discovery

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Description

This quiz covers the non-targeted discovery and subsequent drug development of penicillin and nitrogen mustard chemotherapy drugs. Learn about the history of these important medications.