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HMG-CoA Reductase Inhibitors: Statins and Their Effects

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HMG-CoA Reductase Inhibitors: Statins and Their Effects

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Questions and Answers

What is the primary effect of MTP inhibitors on lipid metabolism?

Reducing LDL levels only

Increasing VLDL and triglyceride synthesis in the liver

Increasing HDL levels

Reducing VLDL and non-HDL levels (correct)

What is the mechanism of action of PCSK9 inhibitors?

Inhibiting the absorption of dietary cholesterol

Inhibiting the production of triglycerides

Increasing the production of LDL receptors (correct)

Reducing the production of HDL

What is the primary side effect of MTP inhibitors?

Increased liver enzymes

GI effects (correct)

Bleeding risk

Muscle weakness

What is the term given to individuals with a BMI of 30 kg/m2 or greater?

Obese Signup and view all the answers

What is the primary mechanism of action of anorexiants?

Suppressing appetite Signup and view all the answers

What is the effect of PCSK9 inhibitors on LDL levels?

Marked decrease Signup and view all the answers

What is the role of genetics in obesity?

Partial role Signup and view all the answers

What is the effect of statins on triglyceride levels?

Small decrease Signup and view all the answers

What is the effect of fibrates on LDL levels?

Small decrease Signup and view all the answers

What is the effect of bile acid sequestrants on HDL levels?

No change Signup and view all the answers