HMG-CoA Reductase Inhibitors: Statins and Their Effects
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Questions and Answers

What is the primary effect of MTP inhibitors on lipid metabolism?

  • Reducing LDL levels only
  • Increasing VLDL and triglyceride synthesis in the liver
  • Increasing HDL levels
  • Reducing VLDL and non-HDL levels (correct)

What is the mechanism of action of PCSK9 inhibitors?

  • Inhibiting the absorption of dietary cholesterol
  • Inhibiting the production of triglycerides
  • Increasing the production of LDL receptors (correct)
  • Reducing the production of HDL

What is the primary side effect of MTP inhibitors?

  • Increased liver enzymes
  • GI effects (correct)
  • Bleeding risk
  • Muscle weakness

What is the term given to individuals with a BMI of 30 kg/m2 or greater?

<p>Obese (C)</p> Signup and view all the answers

What is the primary mechanism of action of anorexiants?

<p>Suppressing appetite (D)</p> Signup and view all the answers

What is the effect of PCSK9 inhibitors on LDL levels?

<p>Marked decrease (B)</p> Signup and view all the answers

What is the role of genetics in obesity?

<p>Partial role (D)</p> Signup and view all the answers

What is the effect of statins on triglyceride levels?

<p>Small decrease (C)</p> Signup and view all the answers

What is the effect of fibrates on LDL levels?

<p>Small decrease (A)</p> Signup and view all the answers

What is the effect of bile acid sequestrants on HDL levels?

<p>No change (A)</p> Signup and view all the answers

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