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What is the common name for HMG CoA Reductase Inhibitors?
What is the common name for HMG CoA Reductase Inhibitors?
Statins
What is the primary use of HMG CoA Reductase Inhibitors?
What is the primary use of HMG CoA Reductase Inhibitors?
Hyperlipidemia (high cholesterol)
Which of these is NOT a common adverse reaction of HMG CoA Reductase Inhibitors?
Which of these is NOT a common adverse reaction of HMG CoA Reductase Inhibitors?
What is the generic name of the drug Crestor?
What is the generic name of the drug Crestor?
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Which of these medications has an auxiliary label to avoid grapefruit?
Which of these medications has an auxiliary label to avoid grapefruit?
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HMG CoA Reductase Inhibitors are enzymes.
HMG CoA Reductase Inhibitors are enzymes.
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HMG CoA Reductase Inhibitors are involved in the final step of cholesterol synthesis.
HMG CoA Reductase Inhibitors are involved in the final step of cholesterol synthesis.
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What is the common ending for medications in the HMG CoA Reductase Inhibitors class?
What is the common ending for medications in the HMG CoA Reductase Inhibitors class?
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What are statins commonly used to treat?
What are statins commonly used to treat?
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Which of the following are enzymes involved in the final step of cholesterol synthesis?
Which of the following are enzymes involved in the final step of cholesterol synthesis?
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Statins help increase clearance of LDL (low-density lipoproteins).
Statins help increase clearance of LDL (low-density lipoproteins).
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Statins are typically dosed once daily in the morning.
Statins are typically dosed once daily in the morning.
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Which of the following is a common adverse reaction to statins?
Which of the following is a common adverse reaction to statins?
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What is the generic name for the brand name drug Crestor?
What is the generic name for the brand name drug Crestor?
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What is the generic name for the brand name drug Pravachol?
What is the generic name for the brand name drug Pravachol?
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What auxiliary label should be provided for Crestor?
What auxiliary label should be provided for Crestor?
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What auxiliary label should be provided for Lipitor, Mevacor, and Pravachol?
What auxiliary label should be provided for Lipitor, Mevacor, and Pravachol?
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Which statement about statins is accurate regarding their effect on LDL cholesterol?
Which statement about statins is accurate regarding their effect on LDL cholesterol?
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Which of the following statements accurately describes the mechanism of action of statins?
Which of the following statements accurately describes the mechanism of action of statins?
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What are potential adverse reactions associated with the use of statins?
What are potential adverse reactions associated with the use of statins?
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Which statement about the administration of statins is true?
Which statement about the administration of statins is true?
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Which of the following correctly identifies a statin and its available dosage form?
Which of the following correctly identifies a statin and its available dosage form?
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What auxiliary label is required for Lipitor, Mevacor, and Pravachol?
What auxiliary label is required for Lipitor, Mevacor, and Pravachol?
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What potential serious condition is associated with muscle tissue breakdown in patients taking statins?
What potential serious condition is associated with muscle tissue breakdown in patients taking statins?
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Which of the following statins is available in an extended release form?
Which of the following statins is available in an extended release form?
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Which enzyme is specifically inhibited by statins to reduce cholesterol synthesis?
Which enzyme is specifically inhibited by statins to reduce cholesterol synthesis?
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What is the recommended timing for administering statins to maximize their effectiveness?
What is the recommended timing for administering statins to maximize their effectiveness?
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Which of the following terms describes muscle inflammation that may occur as an adverse reaction to statins?
Which of the following terms describes muscle inflammation that may occur as an adverse reaction to statins?
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Statins are commonly used to treat hyperlipidemia.
Statins are commonly used to treat hyperlipidemia.
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All statins should be taken in the morning for optimal results.
All statins should be taken in the morning for optimal results.
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Rhabdomyolysis is a common adverse reaction associated with the use of statins.
Rhabdomyolysis is a common adverse reaction associated with the use of statins.
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The common ending for statin medications is -ase.
The common ending for statin medications is -ase.
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Statins inhibit HMG CoA reductase to promote cholesterol synthesis.
Statins inhibit HMG CoA reductase to promote cholesterol synthesis.
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Study Notes
HMG-CoA Reductase Inhibitors (Statins)
- Therapeutic Class: HMG CoA Reductase Inhibitors
- Common Name: Statins
- Common Ending: -statin
- Commonly Used to Treat: Hyperlipidemia (high cholesterol)
- Mechanism of Action: Statins are enzymes that stop the final step in cholesterol production. They inhibit HMG CoA reductase. This, in turn, helps increase the removal of LDL (low-density lipoproteins) from the body.
- Notes: Usually taken once daily, typically in the evening or at bedtime.
- Common Adverse Reactions: Myositis (muscle inflammation), Rhabdomyolysis (muscle breakdown), Muscle cramps/pain, and Liver dysfunction.
- Auxiliary Labels: Avoid antacids containing magnesium, Avoid grapefruit juice.
Available Doses and Forms
- Brand Name: Crestor, Lescol, Lipitor, Mevacor, Pravachol, Zocor
- Generic Name: Rosuvastatin, Fluvastatin, Atorvastatin, Lovastatin, Pravastatin, Simvastatin
- Available Doses & Forms: Vary by brand and generic. Include tablets in various dosages (5mg, 10mg, 20mg, 40mg, 80mg), capsules, and extended-release tablets.
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Description
This quiz focuses on HMG-CoA reductase inhibitors, commonly known as statins, which are used to treat hyperlipidemia. The quiz covers their mechanism of action, common adverse reactions, and available doses and forms. Test your knowledge on these medications and their effects on cholesterol production.
