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Questions and Answers
What is the common name for HMG CoA Reductase Inhibitors?
What is the common name for HMG CoA Reductase Inhibitors?
Statins
What is the primary use of HMG CoA Reductase Inhibitors?
What is the primary use of HMG CoA Reductase Inhibitors?
Hyperlipidemia (high cholesterol)
Which of these is NOT a common adverse reaction of HMG CoA Reductase Inhibitors?
Which of these is NOT a common adverse reaction of HMG CoA Reductase Inhibitors?
- Myositis (inflammation of muscle)
- Muscle cramps/pain
- Heart palpitations (correct)
- Liver dysfunction
- Rhabdomyolysis (breakdown of muscle tissue)
What is the generic name of the drug Crestor?
What is the generic name of the drug Crestor?
Which of these medications has an auxiliary label to avoid grapefruit?
Which of these medications has an auxiliary label to avoid grapefruit?
HMG CoA Reductase Inhibitors are enzymes.
HMG CoA Reductase Inhibitors are enzymes.
HMG CoA Reductase Inhibitors are involved in the final step of cholesterol synthesis.
HMG CoA Reductase Inhibitors are involved in the final step of cholesterol synthesis.
What is the common ending for medications in the HMG CoA Reductase Inhibitors class?
What is the common ending for medications in the HMG CoA Reductase Inhibitors class?
What are statins commonly used to treat?
What are statins commonly used to treat?
Which of the following are enzymes involved in the final step of cholesterol synthesis?
Which of the following are enzymes involved in the final step of cholesterol synthesis?
Statins help increase clearance of LDL (low-density lipoproteins).
Statins help increase clearance of LDL (low-density lipoproteins).
Statins are typically dosed once daily in the morning.
Statins are typically dosed once daily in the morning.
Which of the following is a common adverse reaction to statins?
Which of the following is a common adverse reaction to statins?
What is the generic name for the brand name drug Crestor?
What is the generic name for the brand name drug Crestor?
What is the generic name for the brand name drug Pravachol?
What is the generic name for the brand name drug Pravachol?
What auxiliary label should be provided for Crestor?
What auxiliary label should be provided for Crestor?
What auxiliary label should be provided for Lipitor, Mevacor, and Pravachol?
What auxiliary label should be provided for Lipitor, Mevacor, and Pravachol?
Which statement about statins is accurate regarding their effect on LDL cholesterol?
Which statement about statins is accurate regarding their effect on LDL cholesterol?
Which of the following statements accurately describes the mechanism of action of statins?
Which of the following statements accurately describes the mechanism of action of statins?
What are potential adverse reactions associated with the use of statins?
What are potential adverse reactions associated with the use of statins?
Which statement about the administration of statins is true?
Which statement about the administration of statins is true?
Which of the following correctly identifies a statin and its available dosage form?
Which of the following correctly identifies a statin and its available dosage form?
What auxiliary label is required for Lipitor, Mevacor, and Pravachol?
What auxiliary label is required for Lipitor, Mevacor, and Pravachol?
What potential serious condition is associated with muscle tissue breakdown in patients taking statins?
What potential serious condition is associated with muscle tissue breakdown in patients taking statins?
Which of the following statins is available in an extended release form?
Which of the following statins is available in an extended release form?
Which enzyme is specifically inhibited by statins to reduce cholesterol synthesis?
Which enzyme is specifically inhibited by statins to reduce cholesterol synthesis?
What is the recommended timing for administering statins to maximize their effectiveness?
What is the recommended timing for administering statins to maximize their effectiveness?
Which of the following terms describes muscle inflammation that may occur as an adverse reaction to statins?
Which of the following terms describes muscle inflammation that may occur as an adverse reaction to statins?
Statins are commonly used to treat hyperlipidemia.
Statins are commonly used to treat hyperlipidemia.
All statins should be taken in the morning for optimal results.
All statins should be taken in the morning for optimal results.
Rhabdomyolysis is a common adverse reaction associated with the use of statins.
Rhabdomyolysis is a common adverse reaction associated with the use of statins.
The common ending for statin medications is -ase.
The common ending for statin medications is -ase.
Statins inhibit HMG CoA reductase to promote cholesterol synthesis.
Statins inhibit HMG CoA reductase to promote cholesterol synthesis.
Flashcards
Statin Mechanism
Statin Mechanism
Statins block the enzyme HMG CoA reductase, slowing cholesterol production.
Hyperlipidemia Treatment
Hyperlipidemia Treatment
Statins are commonly used to treat high cholesterol (hyperlipidemia).
HMG CoA Reductase
HMG CoA Reductase
An enzyme critical for cholesterol synthesis.
Statin Adverse Reactions
Statin Adverse Reactions
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Statin Dosage
Statin Dosage
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-statin
-statin
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LDL Clearance
LDL Clearance
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Myositis
Myositis
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Rhabdomyolysis
Rhabdomyolysis
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Hyperlipidemia
Hyperlipidemia
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Crestor
Crestor
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Lipitor
Lipitor
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Grapefruit Caution
Grapefruit Caution
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Antacids
Antacids
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Therapeutic Class
Therapeutic Class
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Common Name
Common Name
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Available Doses & Forms
Available Doses & Forms
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Liver Dysfunction
Liver Dysfunction
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Statin ending
Statin ending
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Statin Use
Statin Use
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Statin Action
Statin Action
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LDL and Statins
LDL and Statins
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Statin Muscle Side Effects
Statin Muscle Side Effects
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Statin Liver Side Effects
Statin Liver Side Effects
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Statin: Avoid Grapefruit
Statin: Avoid Grapefruit
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Statin: Avoid Magnesium Antacids
Statin: Avoid Magnesium Antacids
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Generic Name
Generic Name
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Rosuvastatin
Rosuvastatin
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Fluvastatin
Fluvastatin
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Atorvastatin
Atorvastatin
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Lovastatin
Lovastatin
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Pravastatin
Pravastatin
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Simvastatin
Simvastatin
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What are statins used for?
What are statins used for?
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What do statins inhibit?
What do statins inhibit?
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Common statin side effects?
Common statin side effects?
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Statin dosage and timing
Statin dosage and timing
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Grapefruit and statins
Grapefruit and statins
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What is the therapeutic class of statins?
What is the therapeutic class of statins?
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What are common side effects of statins?
What are common side effects of statins?
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What is the common ending for statin drugs?
What is the common ending for statin drugs?
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Why do statins usually have grapefruit cautions?
Why do statins usually have grapefruit cautions?
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What do statins DO?
What do statins DO?
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What is a common characteristic of statin drug names?
What is a common characteristic of statin drug names?
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What is a common precaution with statins?
What is a common precaution with statins?
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Study Notes
HMG-CoA Reductase Inhibitors (Statins)
- Therapeutic Class: HMG CoA Reductase Inhibitors
- Common Name: Statins
- Common Ending: -statin
- Commonly Used to Treat: Hyperlipidemia (high cholesterol)
- Mechanism of Action: Statins are enzymes that stop the final step in cholesterol production. They inhibit HMG CoA reductase. This, in turn, helps increase the removal of LDL (low-density lipoproteins) from the body.
- Notes: Usually taken once daily, typically in the evening or at bedtime.
- Common Adverse Reactions: Myositis (muscle inflammation), Rhabdomyolysis (muscle breakdown), Muscle cramps/pain, and Liver dysfunction.
- Auxiliary Labels: Avoid antacids containing magnesium, Avoid grapefruit juice.
Available Doses and Forms
- Brand Name: Crestor, Lescol, Lipitor, Mevacor, Pravachol, Zocor
- Generic Name: Rosuvastatin, Fluvastatin, Atorvastatin, Lovastatin, Pravastatin, Simvastatin
- Available Doses & Forms: Vary by brand and generic. Include tablets in various dosages (5mg, 10mg, 20mg, 40mg, 80mg), capsules, and extended-release tablets.
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