Podcast
Questions and Answers
Which of the following best defines immunodeficiency?
Which of the following best defines immunodeficiency?
- An overactive immune response
- Partial or full impairment of the immune system (correct)
- A defense mechanism against cancer cells
- Complete immunity to all infections
What is the primary cause of secondary immunodeficiency?
What is the primary cause of secondary immunodeficiency?
- Autoimmune disorders
- Congenital defects
- Genetic mutations
- Infections like HIV (correct)
What does AIDS stand for?
What does AIDS stand for?
- Acute immunodeficiency disease
- Autoimmune deficiency syndrome
- Acquired immune disorder syndrome
- Acquired immune deficiency syndrome (correct)
What occurs during Stage 1 of HIV infection?
What occurs during Stage 1 of HIV infection?
What is a common misconception about AIDS?
What is a common misconception about AIDS?
What theory suggests the origin of HIV infection in humans?
What theory suggests the origin of HIV infection in humans?
Which of the following conditions is associated with immunodeficiency?
Which of the following conditions is associated with immunodeficiency?
Which term describes the genetic form of immunodeficiency?
Which term describes the genetic form of immunodeficiency?
What condition is characterized by white patches on the tongue and is often a sign of a weakened immune system?
What condition is characterized by white patches on the tongue and is often a sign of a weakened immune system?
Which of the following is a lifestyle change that can reduce modifiable cancer risks for individuals living with HIV/AIDS?
Which of the following is a lifestyle change that can reduce modifiable cancer risks for individuals living with HIV/AIDS?
In the study mentioned, what percentage of HIV positive individuals were found to be co-infected with hepatitis B?
In the study mentioned, what percentage of HIV positive individuals were found to be co-infected with hepatitis B?
What is the primary route of HIV transmission in the UK?
What is the primary route of HIV transmission in the UK?
Which of the following symptoms is associated with a respiratory condition in individuals living with HIV/AIDS?
Which of the following symptoms is associated with a respiratory condition in individuals living with HIV/AIDS?
What is the guideline regarding alcohol consumption for individuals at risk of cancer, particularly those living with HIV?
What is the guideline regarding alcohol consumption for individuals at risk of cancer, particularly those living with HIV?
What is a common complication for HIV positive individuals regarding cancer risk linked to smoking?
What is a common complication for HIV positive individuals regarding cancer risk linked to smoking?
Which virus is associated with the development of oral hairy leukoplakia?
Which virus is associated with the development of oral hairy leukoplakia?
What is a possible effect of having chronic hepatitis C as noted in the study findings?
What is a possible effect of having chronic hepatitis C as noted in the study findings?
What does a viral load test measure?
What does a viral load test measure?
What does U=U stand for in the context of HIV?
What does U=U stand for in the context of HIV?
What is the recommended time frame for taking Post-Exposure Prophylaxis (PEP) after potential HIV exposure?
What is the recommended time frame for taking Post-Exposure Prophylaxis (PEP) after potential HIV exposure?
Which of the following statements is true about Pre-Exposure Prophylaxis (PrEP)?
Which of the following statements is true about Pre-Exposure Prophylaxis (PrEP)?
In the UK, what percentage of people living with HIV are estimated to be diagnosed?
In the UK, what percentage of people living with HIV are estimated to be diagnosed?
What is the primary purpose of Truvada in the context of HIV?
What is the primary purpose of Truvada in the context of HIV?
Which of the following best describes 'viral load'?
Which of the following best describes 'viral load'?
What is the asymptomatic stage of HIV characterized by?
What is the asymptomatic stage of HIV characterized by?
What primarily defines the transition from asymptomatic to symptomatic HIV?
What primarily defines the transition from asymptomatic to symptomatic HIV?
What type of infections can occur during the late-stage HIV or AIDS?
What type of infections can occur during the late-stage HIV or AIDS?
What happens during the seroconversion period in HIV infection?
What happens during the seroconversion period in HIV infection?
Which of the following is considered an AIDS-defining illness?
Which of the following is considered an AIDS-defining illness?
Which symptoms are associated with symptomatic HIV?
Which symptoms are associated with symptomatic HIV?
How does a weakened immune system during late-stage HIV affect the body?
How does a weakened immune system during late-stage HIV affect the body?
What is one potential outcome during the symptomatic stage of HIV without treatment?
What is one potential outcome during the symptomatic stage of HIV without treatment?
Which of the following correctly describes opportunistic infections in late-stage HIV?
Which of the following correctly describes opportunistic infections in late-stage HIV?
What describes the typical duration of the asymptomatic stage of HIV?
What describes the typical duration of the asymptomatic stage of HIV?
What is the highest risk behavior for HIV transmission?
What is the highest risk behavior for HIV transmission?
Which bodily fluids cannot transmit HIV?
Which bodily fluids cannot transmit HIV?
What is the purpose of antiretroviral treatment (ART)?
What is the purpose of antiretroviral treatment (ART)?
What is the first step if you suspect exposure to HIV?
What is the first step if you suspect exposure to HIV?
What should be done within 72 hours of potential HIV exposure?
What should be done within 72 hours of potential HIV exposure?
Which factor increases the risk of contracting HIV?
Which factor increases the risk of contracting HIV?
How can a person confirm if they are infected with HIV?
How can a person confirm if they are infected with HIV?
After a negative HIV test, when should it be repeated?
After a negative HIV test, when should it be repeated?
What is the goal of HIV treatment?
What is the goal of HIV treatment?
What is a common misconception about HIV transmission?
What is a common misconception about HIV transmission?
Flashcards
HIV
HIV
Human Immunodeficiency Virus; a virus that weakens the immune system.
AIDS
AIDS
Acquired Immunodeficiency Syndrome; a condition caused by severe damage to the immune system by HIV.
Immunodeficiency
Immunodeficiency
Partial or full impairment of the immune system.
Primary Immunodeficiency
Primary Immunodeficiency
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Secondary Immunodeficiency
Secondary Immunodeficiency
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Seroconversion illness (stage 1 HIV)
Seroconversion illness (stage 1 HIV)
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HIV transmission
HIV transmission
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Immunodeficiency symptoms
Immunodeficiency symptoms
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Seroconversion
Seroconversion
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Asymptomatic HIV (Stage 2)
Asymptomatic HIV (Stage 2)
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Symptomatic HIV (Stage 3)
Symptomatic HIV (Stage 3)
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Late-stage HIV (Stage 4)
Late-stage HIV (Stage 4)
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Opportunistic Infections
Opportunistic Infections
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AIDS-Defining Illnesses
AIDS-Defining Illnesses
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Non-Hodgkin Lymphoma
Non-Hodgkin Lymphoma
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Candidiasis of the Oesophagus
Candidiasis of the Oesophagus
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Cryptococcosis
Cryptococcosis
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Cytomegalovirus Retinitis
Cytomegalovirus Retinitis
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HIV Transmission Risk - Anal
HIV Transmission Risk - Anal
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HIV Transmission - Oral
HIV Transmission - Oral
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HIV Transmission - Other Routes
HIV Transmission - Other Routes
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HIV Transmission - Virally Suppressed
HIV Transmission - Virally Suppressed
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Higher HIV Risk Factors - STIs
Higher HIV Risk Factors - STIs
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Higher HIV Risk Factors - Needles
Higher HIV Risk Factors - Needles
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HIV Diagnosis - Urgent Action
HIV Diagnosis - Urgent Action
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HIV Diagnosis - Needle Stick
HIV Diagnosis - Needle Stick
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HIV Diagnosis - Patient's Viral Load
HIV Diagnosis - Patient's Viral Load
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HIV Diagnosis - The Only Way
HIV Diagnosis - The Only Way
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Hairy Leukoplakia
Hairy Leukoplakia
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Modifiable Cancer Risk
Modifiable Cancer Risk
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HIV and Smoking
HIV and Smoking
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HIV and Hepatitis B
HIV and Hepatitis B
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HIV and Hepatitis C
HIV and Hepatitis C
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HIV and HPV
HIV and HPV
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Alcohol and Cancer Risk
Alcohol and Cancer Risk
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HIV and Alcohol
HIV and Alcohol
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HIV Transmission in UK
HIV Transmission in UK
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HIV and Body Fluids
HIV and Body Fluids
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Viral Load
Viral Load
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Undetectable Viral Load
Undetectable Viral Load
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Pre-Exposure Prophylaxis (PrEP)
Pre-Exposure Prophylaxis (PrEP)
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Truvada
Truvada
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Post-Exposure Prophylaxis (PEP)
Post-Exposure Prophylaxis (PEP)
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HIV Diagnosis Rate in UK
HIV Diagnosis Rate in UK
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End the Stigma
End the Stigma
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Study Notes
HIV/AIDS and Immunodeficiency
- HIV is a virus that weakens the immune system
- AIDS is a syndrome, not a virus. It is caused when the immune system is severely damaged by HIV
- Immunodeficiency happens when the body's immune system becomes weakened and less capable of fighting off infections, cancers, or other diseases like healthy individuals' immune systems do
- Primary immunodeficiency is genetic. Secondary immunodeficiency can be caused by environmental factors such as HIV, AIDS, or malnutrition.
- Immunodeficiency is a large range of infections, cancers, and other diseases that individuals with a healthy immune system can fight off
- There are different stages of HIV infection:
- Stage 1: Seroconversion Illness (up to 6 weeks). Symptoms similar to influenza (fever, rash, sore throat)
- Stage 2: Asymptomatic Stage. Patient feels fine. The virus is active and damaging the immune system
- Stage 3: Symptomatic HIV. The longer the patient lives with HIV without treatment, the greater the risk of developing infections their immune system can't fight
- Stage 4: Late-Stage HIV. Severe opportunistic infections and cancers occur due to significant immune system damage
HIV-related Illnesses (AIDS-defining)
- Kaposi's sarcoma (KS): A cancer caused by a herpes virus (HHV-8). The virus initially affects endothelial cells within blood vessels and lymphatic vessels. This leads to tumors, and it may appear as skin lesions or in the mouth.
- Candidiasis (Thrush): A fungal infection caused by Candida yeast. It can affect the mouth, esophagus, bronchi, trachea, and lungs. Commonly presented via white plaques on the tongue or throat.
- Tuberculosis (TB): A bacterial infection often affecting the lungs. HIV increases the risk of TB infection.
- Cryptococcal meningitis: A fungus-related brain infection. It is more common and severe in people living with HIV.
- Hairy leukoplakia: White patches on the tongue caused by the Epstein-Barr virus. It is more frequent in people with weakened immune systems like HIV patients.
Transmission of HIV
- HIV is present in bodily fluids such as semen, vaginal fluids, blood, and breast milk
- The most common way people in the UK get HIV is via unprotected anal or vaginal sex
- The risk of HIV transmission through oral sex is very low
- HIV is not transmitted via sweat, urine, or saliva.
Risk Factors for HIV
- Having another sexually transmitted infection (STI): STIs can increase the risk of HIV transmission
- Sharing contaminated needles or syringes: Sharing needles or syringes with an infected person can transmit HIV and other bloodborne infections.
- Receiving unsafe injections, blood transfusions, and tissue transplantation: Unsafe procedures can also put individuals at risk.
- Needle stick injuries: While not as common, needle stick injuries with contaminated needles can transmit several blood-borne infections
Diagnosing HIV
- It is important to seek medical advice immediately if concerned about possible HIV exposure
- If a needle stick occurs, occupational health must be contacted immediately, or A&E if out of hours.
- HIV tests are necessary for diagnosis, and should be repeated at specific intervals if negative
- Results are given as the number of copies of HIV per milliliter of blood.
Treatment for HIV
- Antiretroviral therapy (ART) is used to treat HIV
- The goal of ART is to reduce (or suppress) the viral load to an undetectable level, decreasing the risk of transmission and improving health outcomes. The medication's efficacy is typically measured by the viral load.
Viral Load
- Viral load is the amount of HIV in the blood
- A viral load test measures the number of HIV particles in a blood sample
- The results from the testing are expressed as the number of copies of HIV per milliliter of blood
- An undetectable viral load means the virus is present in low enough concentrations in the body that it cannot be detected by traditional test methods. This essentially means that a person cannot transmit the virus to others.
Pre-Exposure Prophylaxis (PrEP)
- PrEP is a strategy for preventing HIV infection in people at a higher risk of contracting the disease
Post-Exposure Prophylaxis (PEP)
- PEP treatment must be initiated within 72 hours of exposure for maximum effectiveness. This consists of a 28-day regimen of ARV drugs
- It is recommended to take PEP in cases of potential HIV exposure via occupational hazards, or non-occupational exposures
HIV Statistics
- In 2019, the estimated number of people living with HIV in the UK was 105,200
- 94% are diagnosed. 6% do not know that they have the virus.
- 98% of diagnosed HIV patients in the UK are on treatment, with 97% of those who are treated having a non-detectable viral load making them unlikely to transmit the virus.
Learning Outcomes
- There were various general learning outcomes (1.1.2, 1.1.3, and so on.) Note those as relevant to your studies. Specific learning objectives were available but not listed.
Additional Information
- Patient/client care and communication guidelines are essential to remember in providing aid to individuals experiencing any health concern, particularly with respect to HIV or AIDS. Respect the patient's wishes.
- Avoid stigmatizing language, attitudes, or practices when dealing with HIV or AIDS patients.
- There are multiple forms of HIV care and treatment (PEP, PrEP, etc)
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Description
This quiz explores the critical aspects of HIV and AIDS, including their definitions, stages of infection, and immunodeficiency types. Understand how HIV affects the immune system and the differences between primary and secondary immunodeficiency. Test your knowledge on this important health topic.