Podcast
Questions and Answers
Which hepatitis infection is more likely to become chronic?
Which hepatitis infection is more likely to become chronic?
- It depends on the age of acquisition
- Hepatitis B
- Both have the same likelihood
- Hepatitis C (correct)
How is acute hepatitis C infection defined?
How is acute hepatitis C infection defined?
- Positive hep C ribonucleic acid (RNA) for up to six months following initial infection (correct)
- Presence of hepatitis C surface antigen less than six months
- Presence of hepatitis C surface antigen more than six months
- Persistently positive RNA for more than six months
What are common risk factors for both hepatitis B and C infections?
What are common risk factors for both hepatitis B and C infections?
- Injection drug use and unprotected sex (correct)
- Men who have sex with men
- Exposure to infected blood only
- Household contacts of known infected persons only
How is chronic hepatitis B infection defined?
How is chronic hepatitis B infection defined?
What is a significant difference between acute and chronic hepatitis C infections?
What is a significant difference between acute and chronic hepatitis C infections?
What plays a significant role in determining the likelihood of chronicity in HBV infections?
What plays a significant role in determining the likelihood of chronicity in HBV infections?
What antiviral treatment can be discontinued three months postpartum with continued ALT monitoring?
What antiviral treatment can be discontinued three months postpartum with continued ALT monitoring?
Following birth to a hepatitis B surface-antigen positive mother, what should the infant be provided to prevent perinatal infection?
Following birth to a hepatitis B surface-antigen positive mother, what should the infant be provided to prevent perinatal infection?
For hepatitis C, when is treatment not currently recommended for pregnant women of childbearing age?
For hepatitis C, when is treatment not currently recommended for pregnant women of childbearing age?
What can hasten fibrosis progression in patients with HCV?
What can hasten fibrosis progression in patients with HCV?
What should patients avoid to prevent transmission if they have HCV or HBV?
What should patients avoid to prevent transmission if they have HCV or HBV?
What type of HIV primarily accounts for the majority of cases worldwide, including in the United States?
What type of HIV primarily accounts for the majority of cases worldwide, including in the United States?
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What should patients avoid to prevent transmission if they have HCV or HBV?
What should patients avoid to prevent transmission if they have HCV or HBV?
What are the goals of drug therapy for hepatitis B?
What are the goals of drug therapy for hepatitis B?
Which medication is an immunomodulator for hepatitis C treatment?
Which medication is an immunomodulator for hepatitis C treatment?
What is the potential side effect of TDF in hepatitis B treatment?
What is the potential side effect of TDF in hepatitis B treatment?
Which statement about pediatric hepatitis B treatment is true?
Which statement about pediatric hepatitis B treatment is true?
What is a common side effect of Pag interferon in hepatitis C therapy?
What is a common side effect of Pag interferon in hepatitis C therapy?
Special consideration for geriatric patients in hepatitis B includes:
Special consideration for geriatric patients in hepatitis B includes:
What is a distinguishing feature of direct-acting antivirals in hepatitis C treatment?
What is a distinguishing feature of direct-acting antivirals in hepatitis C treatment?
Why are all baby boomers recommended to be screened for hepatitis C?
Why are all baby boomers recommended to be screened for hepatitis C?
What is the primary method used to diagnose HIV1 infection?
What is the primary method used to diagnose HIV1 infection?
Which enzyme allows the synthesis of a DNA molecule from RNA in HIV infection?
Which enzyme allows the synthesis of a DNA molecule from RNA in HIV infection?
What is the range of normal CD4 count in adults?
What is the range of normal CD4 count in adults?
Which cells are primarily affected by HIV infection?
Which cells are primarily affected by HIV infection?
What is the primary goal of HIV therapy?
What is the primary goal of HIV therapy?
Which assay calculates the concentrations of anti-retroviral drugs needed to inhibit HIV replication by 50%?
Which assay calculates the concentrations of anti-retroviral drugs needed to inhibit HIV replication by 50%?
What is the major limitation mentioned for HIV drug resistance testing?
What is the major limitation mentioned for HIV drug resistance testing?
Which NNRTI has been associated with severe life-threatening hepatotoxicity that usually occurs within the first few weeks of initiation?
Which NNRTI has been associated with severe life-threatening hepatotoxicity that usually occurs within the first few weeks of initiation?
What is the recommended initial dosing schedule for nevaripine to minimize the risk of hepatic toxicity?
What is the recommended initial dosing schedule for nevaripine to minimize the risk of hepatic toxicity?
Which NNRTI is reserved for treatment-experienced patients and demonstrates activity against HIV viruses with mutations resistant to other NNRTIs?
Which NNRTI is reserved for treatment-experienced patients and demonstrates activity against HIV viruses with mutations resistant to other NNRTIs?
What are common side effects associated with Real pivorene?
What are common side effects associated with Real pivorene?
Which enzyme metabolizes all NNRTIs according to the text?
Which enzyme metabolizes all NNRTIs according to the text?
What are common adverse effects of protease inhibitors as per the text?
What are common adverse effects of protease inhibitors as per the text?
What is a common class effect of protease inhibitors according to the text?
What is a common class effect of protease inhibitors according to the text?
What is the recommended management strategy for fat maldistribution associated with protease inhibitors according to the text?
What is the recommended management strategy for fat maldistribution associated with protease inhibitors according to the text?
Which drug class of HIV medications must be phosphorylated in target cells before becoming active?
Which drug class of HIV medications must be phosphorylated in target cells before becoming active?
Which drug was the very first one to receive approval in the United States for the treatment of HIV?
Which drug was the very first one to receive approval in the United States for the treatment of HIV?
What is a significant adverse effect associated with zidovudine?
What is a significant adverse effect associated with zidovudine?
Which HIV drug has to be discontinued immediately if lactic acidosis with hepatic steatosis develops?
Which HIV drug has to be discontinued immediately if lactic acidosis with hepatic steatosis develops?
What factors increase the risk of developing lactic acidosis with hepatic steatosis due to HIV medications?
What factors increase the risk of developing lactic acidosis with hepatic steatosis due to HIV medications?
Which NNRTI is no longer recommended for initial treatment due to a higher incidence of rash and hepatotoxicity?
Which NNRTI is no longer recommended for initial treatment due to a higher incidence of rash and hepatotoxicity?
Which NNRTI is commonly associated with central nervous system adverse effects like dizziness and impaired concentration?
Which NNRTI is commonly associated with central nervous system adverse effects like dizziness and impaired concentration?
What is the major advantage of fusion inhibitors over other anti-retroviral drugs according to the text?
What is the major advantage of fusion inhibitors over other anti-retroviral drugs according to the text?
Which integrase inhibitor is co-formulated with a booster agent, reducing the frequency of dosing and potentially causing numerous drug interactions?
Which integrase inhibitor is co-formulated with a booster agent, reducing the frequency of dosing and potentially causing numerous drug interactions?
What is the most common adverse effect associated with elvitegravir, an integrase inhibitor?
What is the most common adverse effect associated with elvitegravir, an integrase inhibitor?
Which scenario warrants caution when using an integrase inhibitor like raltegravir?
Which scenario warrants caution when using an integrase inhibitor like raltegravir?
Why is elvitegravir particularly associated with elevations in creatinine kinase and possibly rhabdomyolysis?
Why is elvitegravir particularly associated with elevations in creatinine kinase and possibly rhabdomyolysis?
Which statement accurately describes the dosing frequency for elvitegravir co-formulated with cobicistat, as per the text?
Which statement accurately describes the dosing frequency for elvitegravir co-formulated with cobicistat, as per the text?
Why is it important for healthcare practitioners to collaborate with HIV patients in selecting a treatment regimen?
Why is it important for healthcare practitioners to collaborate with HIV patients in selecting a treatment regimen?
What factor makes the management of HIV patients challenging?
What factor makes the management of HIV patients challenging?
How does non-adherence to antiretroviral therapy impact treatment outcomes?
How does non-adherence to antiretroviral therapy impact treatment outcomes?
What aspect makes the selection of HIV treatment regimens complex?
What aspect makes the selection of HIV treatment regimens complex?
In HIV management, why should treatment regimens be individualized?
In HIV management, why should treatment regimens be individualized?
What is a critical consideration for healthcare professionals when managing the adverse effects of HIV medications?
What is a critical consideration for healthcare professionals when managing the adverse effects of HIV medications?
Which second-generation INST has a higher genetic barrier to resistance?
Which second-generation INST has a higher genetic barrier to resistance?
What should be done prior to using Mariviric in patients?
What should be done prior to using Mariviric in patients?
Which antiretroviral drug is administered as an IV infusion every two weeks?
Which antiretroviral drug is administered as an IV infusion every two weeks?
What is the black box warning associated with Mariviric?
What is the black box warning associated with Mariviric?
What is the mechanism of action of Phosphamase severe in HIV treatment?
What is the mechanism of action of Phosphamase severe in HIV treatment?
Which HIV medication is a nucleoside reverse transcriptase inhibitor?
Which HIV medication is a nucleoside reverse transcriptase inhibitor?
Which factor contributes to verilogic failure in HIV treatment?
Which factor contributes to verilogic failure in HIV treatment?
What defines verilogic rebound in HIV treatment?
What defines verilogic rebound in HIV treatment?
Why are pediatric patients monitored more frequently for CD4 counts during HIV treatment?
Why are pediatric patients monitored more frequently for CD4 counts during HIV treatment?
What is a challenge in pediatric HIV drug therapy highlighted in the text?
What is a challenge in pediatric HIV drug therapy highlighted in the text?
What consideration is important when prescribing antiretroviral therapy to pregnant females?
What consideration is important when prescribing antiretroviral therapy to pregnant females?
How is verilogic blip different from verilogic rebound in HIV treatment?
How is verilogic blip different from verilogic rebound in HIV treatment?
What is the significance of CD4-T cell counts in monitoring pediatric HIV patients?
What is the significance of CD4-T cell counts in monitoring pediatric HIV patients?
In pediatric patients, why is medication adherence crucial during HIV therapy?
In pediatric patients, why is medication adherence crucial during HIV therapy?
How do verilogic blips differ from verilogic failure in the context of HIV treatment?
How do verilogic blips differ from verilogic failure in the context of HIV treatment?
What role does medication taste play in pediatric HIV treatment adherence?
What role does medication taste play in pediatric HIV treatment adherence?
What is the recommended action for pregnant women with viral loads consistently below 1,000 copies per milliliter during late pregnancy and delivery?
What is the recommended action for pregnant women with viral loads consistently below 1,000 copies per milliliter during late pregnancy and delivery?
What is the primary means of HIV transmission in the healthcare worker population?
What is the primary means of HIV transmission in the healthcare worker population?
What is the recommended PEP regimen for healthcare workers after exposure to HIV?
What is the recommended PEP regimen for healthcare workers after exposure to HIV?
How soon after exposure should post-exposure prophylaxis (PEP) be started to prevent systemic infection?
How soon after exposure should post-exposure prophylaxis (PEP) be started to prevent systemic infection?
Why is adherence emphasized when considering pre-exposure prophylaxis (PrEP) for individuals at risk of HIV infection?
Why is adherence emphasized when considering pre-exposure prophylaxis (PrEP) for individuals at risk of HIV infection?
What is recommended for individuals on PrEP to prevent the development of resistance in the presence of HIV infection?
What is recommended for individuals on PrEP to prevent the development of resistance in the presence of HIV infection?
How often should CD4 counts be checked during the first two years of ART treatment?
How often should CD4 counts be checked during the first two years of ART treatment?