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History of Microscopy in Biological Science

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History of Microscopy in Biological Science

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Questions and Answers

What was the major step in biological science achieved through the use of the first microscope?

Identification of large molecular complexes

Observation of subcellular structures

First observation of cellular architecture of tissues (correct)

Discovery of viruses

How can the overall measurement error in histology be reduced based on the text?

By reducing errors in the instrument, observer, and sample analysis (correct)

By increasing the magnification of the microscope

By improving the observer's subjectivity

By minimizing the use of optical tools

What is a key aspect of Transmission Electron Microscopy (TEM) based on the text?

Increased prediction of cellular functions

Improvement in cellular architecture visualization

Ability to identify cell shapes accurately

Enhanced magnification to observe large molecular complexes (correct)

What is a key advantage of computational microscopy in the context of microscopic images?

Decrease in the degree of error due to technical artifacts Signup and view all the answers

Which precision microscopy technique utilizes antibodies against cell components and metabolic probes for fluorescence analysis?

Fluorescent Microscopy Signup and view all the answers

In Immunohistochemistry (IHC), what forms the basis for identifying the antigen profile of cells?

Proteins inducing antibody generation in different animal species Signup and view all the answers

Which aspect of an instrument refers to the precision of the objective measurements on the image?

Accuracy Signup and view all the answers

What aspect of a sample is crucial for repeated observations and is represented by an unique marker?

Identity Signup and view all the answers

What is the main limitation of using fixed cells and tissues for microscopy?

Static images that do not show movements Signup and view all the answers

In what way do last generation microscopes equipped with high-resolution digital videocameras surpass human vision capabilities?

By discriminating a broader chromatic and intensity light range Signup and view all the answers