History of Glycolysis Discoveries Quiz
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Questions and Answers

What is the net formation of ATP from ADP and Pi in glycolysis?

  • 8 ATP
  • 2 ATP (correct)
  • 6 ATP
  • 4 ATP
  • Why is glycolysis considered irreversible under standard conditions?

  • It has a negative ΔGº (correct)
  • It converts glucose to pyruvate
  • It generates NADH
  • It involves ATP hydrolysis
  • Which phase of glycolysis involves the initial steps that prepare glucose for further breakdown?

  • Preparatory phase (correct)
  • Investment phase
  • Payoff phase
  • Energy generation phase
  • What is the overall standard free-energy change of glycolysis?

    <p>-85 kJ/mol</p> Signup and view all the answers

    Where does glycolysis occur within the cell?

    <p>Cytoplasm</p> Signup and view all the answers

    What is the final product generated in the preparatory phase of glycolysis?

    <p>Fructose-1,6-bisphosphate</p> Signup and view all the answers

    What is the end product of glycolysis?

    <p>Pyruvate</p> Signup and view all the answers

    Which metabolic pathway uses DHAP to produce glycerol 3-phosphate?

    <p>Lipid metabolism</p> Signup and view all the answers

    What form of reducing equivalents does glycolysis generate?

    <p>NADH</p> Signup and view all the answers

    Who discovered that fermentation is caused by microorganisms?

    <p>Louis Pasteur</p> Signup and view all the answers

    Which scientist demonstrated that reactions of glycolysis can be carried out in cell-free yeast extract?

    <p>Eduard Buchner</p> Signup and view all the answers

    What is the significance of glycolysis in the history of biochemistry?

    <p>It is the first metabolic pathway discovered.</p> Signup and view all the answers

    What is the main product of glycolysis?

    <p>Pyruvate</p> Signup and view all the answers

    In the context of glycolysis, what is the function of zymase?

    <p>Catalyze the conversion of glucose to pyruvate</p> Signup and view all the answers

    Where does glycolysis take place in cells?

    <p>Cytoplasm</p> Signup and view all the answers

    Which scientist contributed to elucidating the complete pathways for glycolysis?

    <p>Otto Fritz Meyerhof</p> Signup and view all the answers

    What process is considered the first metabolic pathway to be elucidated?

    <p>Glycolysis</p> Signup and view all the answers

    What is a key aspect explaining the difference between cyclic and spiral pathways?

    <p>Lengthening or shortening of the substrate by monomeric units</p> Signup and view all the answers

    What type of metabolic pathway exhibits both progressive and cyclical aspects?

    <p>Spiral</p> Signup and view all the answers

    Which metabolic pathway involves the regeneration or recycling of intermediates or products back to the starting point?

    <p>Cyclic</p> Signup and view all the answers

    Why is glucose considered the most important source of energy for living organisms?

    <p>Efficient ATP production through glycolysis</p> Signup and view all the answers

    Which metabolic pathway involves a series of enzymatic steps converting glucose to pyruvate?

    <p>Glycolysis</p> Signup and view all the answers

    Which component of yeast extract was later shown to consist of metal ions, ATP, ADP, and coenzymes like NAD?

    <p>&quot;Cozymase&quot;</p> Signup and view all the answers

    What characteristic makes glycolysis a suitable metabolic pathway for both aerobic and anaerobic respiration?

    <p>Rapid ATP production from glucose</p> Signup and view all the answers

    What is the result of splitting Fructose-1,6-biphosphate in the first phase of glycolysis?

    <p>2 molecules of Glyceraldehyde-3-phosphate</p> Signup and view all the answers

    How many ATP molecules are required as an investment to activate a glucose molecule for cleavage in glycolysis?

    <p>2 ATP molecules</p> Signup and view all the answers

    During the energy generation phase of glycolysis, what is the net gain of ATP molecules per molecule of glucose oxidized?

    <p>2 moles</p> Signup and view all the answers

    Which enzyme rapidly phosphorylates glucose entering the cell in the first reaction of glycolysis?

    <p>Hexokinase</p> Signup and view all the answers

    What is the main product of the second half of the glycolysis pathway?

    <p>2 molecules of Pyruvate</p> Signup and view all the answers

    How many even higher-energy NADH molecules are produced during the second half of glycolysis per molecule of glucose oxidized?

    <p>2</p> Signup and view all the answers

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