30 Questions
What is the net formation of ATP from ADP and Pi in glycolysis?
2 ATP
Why is glycolysis considered irreversible under standard conditions?
It has a negative ΔGº
Which phase of glycolysis involves the initial steps that prepare glucose for further breakdown?
Preparatory phase
What is the overall standard free-energy change of glycolysis?
-85 kJ/mol
Where does glycolysis occur within the cell?
Cytoplasm
What is the final product generated in the preparatory phase of glycolysis?
Fructose-1,6-bisphosphate
What is the end product of glycolysis?
Pyruvate
Which metabolic pathway uses DHAP to produce glycerol 3-phosphate?
Lipid metabolism
What form of reducing equivalents does glycolysis generate?
NADH
Who discovered that fermentation is caused by microorganisms?
Louis Pasteur
Which scientist demonstrated that reactions of glycolysis can be carried out in cell-free yeast extract?
Eduard Buchner
What is the significance of glycolysis in the history of biochemistry?
It is the first metabolic pathway discovered.
What is the main product of glycolysis?
Pyruvate
In the context of glycolysis, what is the function of zymase?
Catalyze the conversion of glucose to pyruvate
Where does glycolysis take place in cells?
Cytoplasm
Which scientist contributed to elucidating the complete pathways for glycolysis?
Otto Fritz Meyerhof
What process is considered the first metabolic pathway to be elucidated?
Glycolysis
What is a key aspect explaining the difference between cyclic and spiral pathways?
Lengthening or shortening of the substrate by monomeric units
What type of metabolic pathway exhibits both progressive and cyclical aspects?
Spiral
Which metabolic pathway involves the regeneration or recycling of intermediates or products back to the starting point?
Cyclic
Why is glucose considered the most important source of energy for living organisms?
Efficient ATP production through glycolysis
Which metabolic pathway involves a series of enzymatic steps converting glucose to pyruvate?
Glycolysis
Which component of yeast extract was later shown to consist of metal ions, ATP, ADP, and coenzymes like NAD?
"Cozymase"
What characteristic makes glycolysis a suitable metabolic pathway for both aerobic and anaerobic respiration?
Rapid ATP production from glucose
What is the result of splitting Fructose-1,6-biphosphate in the first phase of glycolysis?
2 molecules of Glyceraldehyde-3-phosphate
How many ATP molecules are required as an investment to activate a glucose molecule for cleavage in glycolysis?
2 ATP molecules
During the energy generation phase of glycolysis, what is the net gain of ATP molecules per molecule of glucose oxidized?
2 moles
Which enzyme rapidly phosphorylates glucose entering the cell in the first reaction of glycolysis?
Hexokinase
What is the main product of the second half of the glycolysis pathway?
2 molecules of Pyruvate
How many even higher-energy NADH molecules are produced during the second half of glycolysis per molecule of glucose oxidized?
2
Test your knowledge on the history of glycolysis discoveries, including the separation of yeast extract by Arthur Harden and William Young, and the elucidation of complete pathways for glycolysis in 1940 with the contributions of Otto Fritz Meyerhof.
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