History of Glycolysis Discoveries Quiz

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Questions and Answers

What is the net formation of ATP from ADP and Pi in glycolysis?

  • 8 ATP
  • 2 ATP (correct)
  • 6 ATP
  • 4 ATP

Why is glycolysis considered irreversible under standard conditions?

  • It has a negative ΔGº (correct)
  • It converts glucose to pyruvate
  • It generates NADH
  • It involves ATP hydrolysis

Which phase of glycolysis involves the initial steps that prepare glucose for further breakdown?

  • Preparatory phase (correct)
  • Investment phase
  • Payoff phase
  • Energy generation phase

What is the overall standard free-energy change of glycolysis?

<p>-85 kJ/mol (C)</p> Signup and view all the answers

Where does glycolysis occur within the cell?

<p>Cytoplasm (C)</p> Signup and view all the answers

What is the final product generated in the preparatory phase of glycolysis?

<p>Fructose-1,6-bisphosphate (B)</p> Signup and view all the answers

What is the end product of glycolysis?

<p>Pyruvate (C)</p> Signup and view all the answers

Which metabolic pathway uses DHAP to produce glycerol 3-phosphate?

<p>Lipid metabolism (A)</p> Signup and view all the answers

What form of reducing equivalents does glycolysis generate?

<p>NADH (C)</p> Signup and view all the answers

Who discovered that fermentation is caused by microorganisms?

<p>Louis Pasteur (A)</p> Signup and view all the answers

Which scientist demonstrated that reactions of glycolysis can be carried out in cell-free yeast extract?

<p>Eduard Buchner (A)</p> Signup and view all the answers

What is the significance of glycolysis in the history of biochemistry?

<p>It is the first metabolic pathway discovered. (D)</p> Signup and view all the answers

What is the main product of glycolysis?

<p>Pyruvate (C)</p> Signup and view all the answers

In the context of glycolysis, what is the function of zymase?

<p>Catalyze the conversion of glucose to pyruvate (D)</p> Signup and view all the answers

Where does glycolysis take place in cells?

<p>Cytoplasm (C)</p> Signup and view all the answers

Which scientist contributed to elucidating the complete pathways for glycolysis?

<p>Otto Fritz Meyerhof (A)</p> Signup and view all the answers

What process is considered the first metabolic pathway to be elucidated?

<p>Glycolysis (A)</p> Signup and view all the answers

What is a key aspect explaining the difference between cyclic and spiral pathways?

<p>Lengthening or shortening of the substrate by monomeric units (B)</p> Signup and view all the answers

What type of metabolic pathway exhibits both progressive and cyclical aspects?

<p>Spiral (B)</p> Signup and view all the answers

Which metabolic pathway involves the regeneration or recycling of intermediates or products back to the starting point?

<p>Cyclic (A)</p> Signup and view all the answers

Why is glucose considered the most important source of energy for living organisms?

<p>Efficient ATP production through glycolysis (D)</p> Signup and view all the answers

Which metabolic pathway involves a series of enzymatic steps converting glucose to pyruvate?

<p>Glycolysis (C)</p> Signup and view all the answers

Which component of yeast extract was later shown to consist of metal ions, ATP, ADP, and coenzymes like NAD?

<p>&quot;Cozymase&quot; (A)</p> Signup and view all the answers

What characteristic makes glycolysis a suitable metabolic pathway for both aerobic and anaerobic respiration?

<p>Rapid ATP production from glucose (D)</p> Signup and view all the answers

What is the result of splitting Fructose-1,6-biphosphate in the first phase of glycolysis?

<p>2 molecules of Glyceraldehyde-3-phosphate (A)</p> Signup and view all the answers

How many ATP molecules are required as an investment to activate a glucose molecule for cleavage in glycolysis?

<p>2 ATP molecules (C)</p> Signup and view all the answers

During the energy generation phase of glycolysis, what is the net gain of ATP molecules per molecule of glucose oxidized?

<p>2 moles (B)</p> Signup and view all the answers

Which enzyme rapidly phosphorylates glucose entering the cell in the first reaction of glycolysis?

<p>Hexokinase (C)</p> Signup and view all the answers

What is the main product of the second half of the glycolysis pathway?

<p>2 molecules of Pyruvate (D)</p> Signup and view all the answers

How many even higher-energy NADH molecules are produced during the second half of glycolysis per molecule of glucose oxidized?

<p>2 (A)</p> Signup and view all the answers

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