History of Blood Transfusion

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Questions and Answers

Who performed the first successful human-to-human blood transfusion?

  • James Blundell (correct)
  • Pope Innocent VII
  • Alexis Carrel
  • Samuel Armstrong Lane

Who assisted Samuel Armstrong Lane in performing the first blood transfusion?

  • James Blundell (correct)
  • Pope Innocent VII
  • No one
  • Alexis Carrel

Which blood group is the most commonly recognized according to the text?

  • O (correct)
  • AB
  • B
  • A

What did Alexis Carrel propose in 1908?

<p>A method to stop blood clotting (D)</p> Signup and view all the answers

Who discovered that O blood can be given to a person with any blood type?

<p>Roger Lee (D)</p> Signup and view all the answers

Who reported sodium citrate as an anticoagulant for transfusion?

<p>Lewisohn (B)</p> Signup and view all the answers

Who directed the Plasma for Britain program for relief of English war victims?

<p>Charles R. Drew (B)</p> Signup and view all the answers

Who demonstrated the feasibility of cryopreservation as a form of anticoagulation?

<p>R.Weil (C)</p> Signup and view all the answers

What was the main purpose of introducing acid citrate dextrose (ACD) solution?

<p>To store blood and blood cells for a longer period (D)</p> Signup and view all the answers

What was the significance of the Association of American Blood Banks (AABB) established in 1947?

<p>It advanced the common goals of American blood banks and blood donation (D)</p> Signup and view all the answers

What did the development of refrigerated centrifuges contribute to in the field of blood banking?

<p>Preparation of therapeutic blood components (B)</p> Signup and view all the answers

What was the primary purpose of introducing the red blood cell nutrient in 1983?

<p>To prolong the storage life of blood and blood cells to 42 days (B)</p> Signup and view all the answers

What was the purpose of performing the first screening test for HTLV-I virus (anti HTLV-I) in 1989?

<p>To identify abnormal antibodies (B)</p> Signup and view all the answers

What was the significance of introducing Rh immunoglobulin commercially in 1967?

<p>It prevented Rh disease in infants of Rh-negative mothers (C)</p> Signup and view all the answers

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Study Notes

Blood Transfusion Milestones

  • First successful human-to-human blood transfusion was performed by Samuel Armstrong Lane.
  • Lane was assisted by his colleagues in this pioneering medical procedure.

Blood Type Discoveries

  • O blood type is recognized as the universal donor, able to be given to individuals with any blood type.
  • Alexis Carrel proposed advancements in blood vessel surgery in 1908, contributing to transfusion techniques.

Anticoagulants and Blood Preservation

  • Sodium citrate was reported as an effective anticoagulant for blood transfusions, improving safety and efficacy.
  • The Plasma for Britain program, led by a prominent figure, aimed to provide relief to English war victims by ensuring blood supply.

Cryopreservation and Blood Banking Innovation

  • Demonstration of cryopreservation's feasibility as a method of anticoagulation opened new avenues in blood storage and longevity.
  • Acid citrate dextrose (ACD) solution was introduced primarily to enhance the preservation of blood components.

Organizational and Technological Advances

  • The establishment of the Association of American Blood Banks (AABB) in 1947 was significant for standardizing blood banking practices and ensuring quality control.
  • Development of refrigerated centrifuges greatly advanced blood banking by allowing efficient separation of blood components.

Nutrient Development and Testing

  • Introduced in 1983, the red blood cell nutrient aimed to improve the quality and viability of stored red cells.
  • First screening test for HTLV-I virus (anti HTLV-I), performed in 1989, was essential for ensuring blood safety from this infectious agent.

Rh Immunoglobulin Impact

  • Commercial introduction of Rh immunoglobulin in 1967 was significant in preventing Rh incompatibility during pregnancy, protecting both mothers and infants.

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