History of Antibiotics Development
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Questions and Answers

Which term refers to the list of bacterial species that an antibiotic acts on?

  • Spectrum of activity (correct)
  • Mechanism of action
  • Bacterial distribution
  • Antibiotic discovery
  • What is the characteristic of antibiotics with a narrow spectrum of activity?

  • They act on a wide range of bacteria
  • They target viruses instead of bacteria
  • They are effective against a limited number of bacterial species (correct)
  • They are most effective against resistant bacteria
  • Which bacterial class has a resistance rate ranging from 10% to 50%?

  • Sensitive species
  • Moderately sensitive species
  • Resistant species
  • Inconsistently sensitive species (correct)
  • When was the first antibiotic, penicillin G, discovered?

    <p>1942</p> Signup and view all the answers

    Which term describes the level at which antibiotics act within bacterial structures or metabolic reactions?

    <p>Site of action</p> Signup and view all the answers

    What effect did antibiotics have on certain infectious diseases after 1945?

    <p>Reduced mortality rates</p> Signup and view all the answers

    Which type of antibiotics inhibits the elongation phase by preventing the attachment of new amino acid-tRNA complexes to the ribosome?

    <p>Tetracyclines</p> Signup and view all the answers

    What is the main mechanism of action of tetracyclines?

    <p>Prevention of protein synthesis elongation</p> Signup and view all the answers

    Which antibiotic acts specifically on Gram-positive bacteria, such as resistant staphylococci and streptococci, by inhibiting the initiation phase of protein synthesis?

    <p>Linézolide</p> Signup and view all the answers

    Which type of antibiotics is bactériostatique, preventing bacterial multiplication without killing them?

    <p>Tetracyclines</p> Signup and view all the answers

    Which antibiotic, even though it doesn't belong to any specific category, acts only on Gram-positive bacteria like staphylococci and streptococci?

    <p>Linézolide</p> Signup and view all the answers

    Which antibiotic is known for causing significant auditory toxicity?

    <p>Gentamycine</p> Signup and view all the answers

    Which of the following statements about antibiotics is true?

    <p>The discovery of antibiotics has increased average human life expectancy by around 15 years.</p> Signup and view all the answers

    What is a major consequence of excessive antibiotic use?

    <p>Bacteria develop resistance by exchanging resistance genes.</p> Signup and view all the answers

    Which of the following is NOT a major class of antibiotics?

    <p>Tetracyclines</p> Signup and view all the answers

    What structural component do penicillins and cephalosporins share?

    <p>A $\beta$-lactam ring</p> Signup and view all the answers

    Against which types of bacteria are penicillins typically effective?

    <p>Gram-positive cocci (except penicillinase producers), gram-negative cocci, and anaerobes</p> Signup and view all the answers

    What is the relationship between research into new antibiotics and efforts to modify existing molecules?

    <p>Research into new antibiotics has slowed down, with more effort put into modifying existing molecules.</p> Signup and view all the answers

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