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Histopathological Features of Oral Pathologies

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What is the primary site of metastasizing ameloblastoma?

Mandible

What radiographic feature is associated with ameloblastoma?

Negative in x-ray

What is the characteristic that defines metastasizing ameloblastoma?

Clinical behavior

What is the treatment of choice for extraosseous ameloblastoma?

Conservative surgical excision

What is a characteristic histopathological feature of intraosseous ameloblastoma that can also be seen in extraosseous ameloblastoma?

All histopathological features

What is the primary reason for the surgical removal of ameloblastoma with a safety margin?

To prevent recurrence

What is the significance of the different histopathologic patterns of ameloblastoma?

They have no clinical significance

Which type of ameloblastoma has a more favorable prognosis?

Luminal and intraluminal unicystic ameloblastoma

What is the recommended treatment for luminal and intraluminal unicystic ameloblastoma?

Enucleation

What is the recommended reading material for students to review the histopathological classification of odontogenic tumors?

Both of the above

What is the characteristic histopathological feature of the follicular pattern of basal cell ameloblastoma?

Composed of nests of uniform basaloid cells

What is the primary reason for the desmoplastic pattern of ameloblastoma?

Increased production of transforming growth factor B (TGF-B)

What is the main reason for including an area of bone beyond the apparent radiographic margin in the treatment of ameloblastoma?

Because the tumor tends to infiltrate between intact cancellous bone trabeculae before bone resorption becomes radiographically evident

What is the characteristic feature of the plexiform pattern of ameloblastoma?

Long anastomosing cords of odontogenic epithelium in connective tissue stroma

What is the prognosis of ameloblastoma?

It has a high recurrence rate

Which type of ameloblastoma is the most common?

Conventional or classical or intraosseous ameloblastoma

What is the characteristic radiographic feature of ameloblastoma?

Multilocular radiolucency with a honeycomb or soap-bubble appearance

What is the clinical behavior of metastasizing ameloblastoma?

It is a highly aggressive tumor with rapid metastasis

What is the characteristic histopathological feature of extraosseous ameloblastoma?

Mixed follicular and plexiform pattern

What is the primary treatment option for malignant ameloblastomas?

Surgical excision

What is the most common precursor of primary intraosseous carcinoma?

Radicular/residual cysts

What is a characteristic feature of ameloblastic carcinoma?

Presence of dysplasia

What is the most common site of metastasis for ameloblastoma?

Lungs

What is the malignant counterpart of ameloblastoma?

Ameloblastic carcinoma

What is the most common odontogenic tumor excluding odontomas?

Ameloblastoma

What is the primary composition of odontogenic tumors of the jaws?

Odontogenic epithelium and ectomesenchyme

What is the most common benign odontogenic tumor?

Ameloblastoma

What is the characteristics of ameloblastoma?

Progressively growing with a tendency for local recurrence

What is the composition of mixed odontogenic tumors?

Both odontogenic epithelium and ectomesenchyme

Where are odontogenic tumors typically found?

Exclusively in the mandible and maxilla, and occasionally in the gingiva

What is the primary location where unicystic ameloblastoma most commonly occurs?

Mandible posterior region

Which of the following histopathologic variants of unicystic ameloblastoma is characterized by a cyst wall lined totally or partially by ameloblastic epithelium?

Luminal

What is the recommended treatment for mural type of unicystic ameloblastoma?

Marginal resection

What is the characteristic feature of extraosseous peripheral ameloblastoma?

Painless, sessile, exophytic mass with smooth or papillary surface

What is the recommended follow-up period for unicystic ameloblastoma?

At least 25 years

Which of the following is a characteristic radiographic feature of unicystic ameloblastoma?

Well-defined unilocular radiolucency

What is the age range when unicystic ameloblastoma is usually diagnosed?

2nd decade

What is the most common association with unicystic ameloblastoma on radiographs?

Unerupted tooth

What is the term for the ameloblastoma that occurs in the soft tissue of gingiva or edentulous alveolar areas?

Extraosseous ameloblastoma

What is the percentage of all ameloblastomas that unicystic ameloblastoma accounts for?

5-22%

What defines a benign odontogenic tumor composed of both odontogenic epithelium and ectomesenchyme?

Combination of both epithelial and ectomesenchymal origin

What is the most common type of odontogenic tumor that arises from odontogenic epithelium only?

Ameloblastoma

What is the composition of odontogenic tumors that arise from odontogenic ectomesenchyme only?

Dental papilla and dental follicle

What is the characteristic feature of mixed odontogenic tumors?

Combination of both epithelial and ectomesenchymal origin

What is the significance of understanding the spectrum of odontogenic tumors?

To understand the variation in radiological and histopathological features

What is a characteristic feature of ameloblastic fibroma on radiographic examination?

Well-defined unilocular or multilocular radiolucent lesion

What is the primary component of the mesenchymal portion of an ameloblastic fibroma?

Myxoid tissue with stellate cells

What is the recommended treatment for extensive destructive ameloblastic fibroma?

Radical surgical removal

What is the characteristic feature of odontomas?

Mixed epithelial and mesenchymal tumor-like malformations

What is the primary concern for patients with Gardner's syndrome?

High risk of transformation of colorectal polyps into adenocarcinoma

What is the typical location of Calcifying Epithelial Odontogenic Tumor (Pindborg tumor)?

Posterior area of the mandible

What is the characteristic histopathological feature of Calcifying Epithelial Odontogenic Tumor (Pindborg tumor)?

Discrete islands of neoplastic epithelial cells with prominent intercellular bridges

What is a common radiographic feature of Calcifying Epithelial Odontogenic Tumor (Pindborg tumor)?

A well-circumscribed, multilocular radiolucency

What is the characteristic protein secreted by Calcifying Epithelial Odontogenic Tumor (Pindborg tumor)?

Amyloid protein

What is the histopathological feature of Calcifying Epithelial Odontogenic Tumor (Pindborg tumor) that may raise the possibility of malignancy?

Pleomorphism of nuclei

What is the age range of patients commonly affected by odontogenic myxoma?

1-73

What is the characteristic radiographic appearance of odontogenic myxoma?

Honeycomb or soap bubble appearance

What is the histopathological characteristic of odontogenic myxoma?

Loosely textured tissue with large stellate or fusiform cells

What is the composition of mixed odontogenic tumors?

Both odontogenic epithelium and ectomesenchyme

What is the most common type of benign odontogenic tumor?

Odontoma

What is the characteristic radiographic feature of cementoblastoma?

A radiopaque mass with a thin radiolucent rim

What is the primary composition of mixed odontogenic tumors?

Both odontogenic epithelium and ectomesenchyme

What is the treatment of choice for cementoblastoma?

Surgical extraction of the tooth together with the attached calcified mass

What is the characteristic histopathological feature of cementoblastoma?

Calcified cementum-like material with reversal lines

What is the most common site of ameloblastic fibroma?

Posterior mandible

What is a characteristic clinical feature of odontomas?

They are frequently associated with unerupted tooth

What is the main difference between compound and complex odontoma?

Macroscopic appearance

What is the radiographic appearance of compound odontoma?

A collection of tooth-like structures

What is the histopathological feature of complex odontoma?

Mature tubular dentin that encloses clefts or hollow circular structures

What is the macroscopic appearance of complex odontoma?

A white bony hard mass

What is the prognosis of odontoma?

Good

What is the treatment of choice for odontoma?

Surgical removal

What is the difference between compound and complex odontoma in terms of location?

Compound odontoma occurs in the anterior maxilla, while complex odontoma occurs in the posterior mandible

What is the characteristic histopathological feature of compound odontoma?

Multiple structures resembling small single rooted teeth

What is the radiographic appearance of complex odontoma?

A disorganized mass of calcified tissue

What is the characteristic clinical feature of adenomatoid odontogenic tumor?

Painless expansion of bone

What is the classification of adenomatoid odontogenic tumor?

Epithelial odontogenic tumor

What is the characteristic radiographic feature of adenomatoid odontogenic tumor?

Well-defined unilocular radiolucency with fine radiopacities

What is the significance of the tumor's capsule in adenomatoid odontogenic tumor?

It allows easy removal from bone

What is the characteristic histopathological feature of adenomatoid odontogenic tumor?

Masses, sheets or strands of spindle cells in scanty fibrous stroma

This quiz covers the histopathological features of various oral pathologies, including basal cell carcinoma and desmoplastic ameloblastoma.

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