Podcast
Questions and Answers
The nervous tissue is derived from the ______ germ layer.
The nervous tissue is derived from the ______ germ layer.
ectoderm
The outer region of the brain is primarily composed of ______ matter, while the inner region of the spinal cord consists of ______ matter.
The outer region of the brain is primarily composed of ______ matter, while the inner region of the spinal cord consists of ______ matter.
gray, gray
[Blank] are the phagocytes of the nervous tissue, migrating through the CNS to engulf infectious agents and cellular debris.
[Blank] are the phagocytes of the nervous tissue, migrating through the CNS to engulf infectious agents and cellular debris.
Microglia
The ______ is the functional unit of nervous tissue, responsible for transmitting electrical and chemical signals.
The ______ is the functional unit of nervous tissue, responsible for transmitting electrical and chemical signals.
[Blank] are equivalent to the rough endoplasmic reticulum in other cells and are responsible for protein synthesis in neurons.
[Blank] are equivalent to the rough endoplasmic reticulum in other cells and are responsible for protein synthesis in neurons.
A ______ neuron has a single axon and multiple dendrites, making it a common type of neuron in the central nervous system.
A ______ neuron has a single axon and multiple dendrites, making it a common type of neuron in the central nervous system.
The ______ substance, formed by glial cells, insulates nerve fibers in the CNS and PNS, facilitating faster signal transmission.
The ______ substance, formed by glial cells, insulates nerve fibers in the CNS and PNS, facilitating faster signal transmission.
The distinguishing microscopic features of different types of neurons are the number of processes, the positioning of the soma, and the arrangement of ______.
The distinguishing microscopic features of different types of neurons are the number of processes, the positioning of the soma, and the arrangement of ______.
A key histological difference between gray matter in the cerebrum and the cerebellum is the arrangement of cells into cortical layers in the ______ and the presence of Purkinje cells in the ______.
A key histological difference between gray matter in the cerebrum and the cerebellum is the arrangement of cells into cortical layers in the ______ and the presence of Purkinje cells in the ______.
[Blank] are glial cells responsible for myelinating axons within the central nervous system.
[Blank] are glial cells responsible for myelinating axons within the central nervous system.
The meningeal layer directly attached to the surface of the brain and spinal cord is the ______.
The meningeal layer directly attached to the surface of the brain and spinal cord is the ______.
The ______ mater is the middle meningeal layer and is characterized by a web-like appearance due to its trabeculae.
The ______ mater is the middle meningeal layer and is characterized by a web-like appearance due to its trabeculae.
The outermost meningeal layer, notable for its thickness and attachment to the periosteum of the skull, is the ______ mater.
The outermost meningeal layer, notable for its thickness and attachment to the periosteum of the skull, is the ______ mater.
The ______ cells, line the ventricles of the brain and the central canal of the spinal cord aiding in the production and circulation of cerebrospinal fluid.
The ______ cells, line the ventricles of the brain and the central canal of the spinal cord aiding in the production and circulation of cerebrospinal fluid.
[Blank] form part of the blood-brain barrier, regulate interstitial fluid composition, and provide structural support to the CNS.
[Blank] form part of the blood-brain barrier, regulate interstitial fluid composition, and provide structural support to the CNS.
In the spinal cord, the ______ horns contain interneurons and receive sensory fibers, whereas the ______ horns contain multipolar motor neurons.
In the spinal cord, the ______ horns contain interneurons and receive sensory fibers, whereas the ______ horns contain multipolar motor neurons.
A ______ is a bundle of axons in the peripheral nervous system, while a ______ refers to a bundle of axons in the central nervous system.
A ______ is a bundle of axons in the peripheral nervous system, while a ______ refers to a bundle of axons in the central nervous system.
A key difference between a spinal ganglion and an autonomic ganglion is the presence of ______ cell bodies in the spinal ganglion and ______ neuronal cell bodies in the autonomic ganglion.
A key difference between a spinal ganglion and an autonomic ganglion is the presence of ______ cell bodies in the spinal ganglion and ______ neuronal cell bodies in the autonomic ganglion.
The three layers of connective tissue in the PNS are the ______, ______, and ______.
The three layers of connective tissue in the PNS are the ______, ______, and ______.
[Blank] cells surround and insulate PNS axons and myelinate those with large diameters, allowing for faster action potential propagation.
[Blank] cells surround and insulate PNS axons and myelinate those with large diameters, allowing for faster action potential propagation.
In myelinated nerve fibers, the myelin sheath prevents ion flow except at the ______, enhancing the speed of conduction.
In myelinated nerve fibers, the myelin sheath prevents ion flow except at the ______, enhancing the speed of conduction.
The ______ is the outer connective tissue coat of a nerve
The ______ is the outer connective tissue coat of a nerve
The middle layer of connective tissue in a nerve, that surrounds each bundle of nerve fibers is the ______.
The middle layer of connective tissue in a nerve, that surrounds each bundle of nerve fibers is the ______.
The connective tissue layer that surrounds individual nerve fibers is the ______.
The connective tissue layer that surrounds individual nerve fibers is the ______.
Unlike oligodendrocytes, ______ cells only myelinate one axon segment.
Unlike oligodendrocytes, ______ cells only myelinate one axon segment.
[Blank] glial cells regulate the exchange of nutrients and waste for cell bodies in PNS ganglia.
[Blank] glial cells regulate the exchange of nutrients and waste for cell bodies in PNS ganglia.
The cerebral cortex layers include the Molecular layer, External granular layer, External pyramidal layer, Internal granular layer, Internal pyramidal layer and the ______ layer.
The cerebral cortex layers include the Molecular layer, External granular layer, External pyramidal layer, Internal granular layer, Internal pyramidal layer and the ______ layer.
In the spinal cord, the ______ matter is peripherally located
In the spinal cord, the ______ matter is peripherally located
In the spinal cord, the ______ horns contain interneurons and receives sensory fibers.
In the spinal cord, the ______ horns contain interneurons and receives sensory fibers.
In regards to Central Nervous System, ______ myelinates and insulates CNS axons.
In regards to Central Nervous System, ______ myelinates and insulates CNS axons.
[Blank] are the cells that form part of the blood-brain barrier.
[Blank] are the cells that form part of the blood-brain barrier.
The ______ mater is consists of flattened mesenchymal derived cells.
The ______ mater is consists of flattened mesenchymal derived cells.
The ______ cell is classified as phagocytic and moves throughout the Central Nervous System.
The ______ cell is classified as phagocytic and moves throughout the Central Nervous System.
In the PNS the ______ cells surround and insulate axons and myelinate those having large diameters
In the PNS the ______ cells surround and insulate axons and myelinate those having large diameters
A major function of ______ cells is to electrically insulate PNS cell bodies
A major function of ______ cells is to electrically insulate PNS cell bodies
In unmyelinated nerve fibers there is no multiple wrapping, smaller diameter axons and the ______ are still present.
In unmyelinated nerve fibers there is no multiple wrapping, smaller diameter axons and the ______ are still present.
In myelinated nerve fibers, the myelin sheath is responsible for preventing the loss of nerve ______.
In myelinated nerve fibers, the myelin sheath is responsible for preventing the loss of nerve ______.
The three components of Peripheral Nervous System include Nerve, ______ and Nerve Endings
The three components of Peripheral Nervous System include Nerve, ______ and Nerve Endings
The two types of Central Neuroglia are Protoplasmic and ______
The two types of Central Neuroglia are Protoplasmic and ______
The Cerebrum is divided between a ______ and White Matter
The Cerebrum is divided between a ______ and White Matter
The ability of oligodendrocytes to speed up action potential propagation along axons is due to their capacity to ______ axons in the CNS.
The ability of oligodendrocytes to speed up action potential propagation along axons is due to their capacity to ______ axons in the CNS.
Unlike neurons, ______ in the CNS can replicate to occupy spaces left by dying neurons, playing a role in tissue repair and maintenance.
Unlike neurons, ______ in the CNS can replicate to occupy spaces left by dying neurons, playing a role in tissue repair and maintenance.
Central nervous system support and organization are mainly provided by ______ because they regulate the interstitial fluid.
Central nervous system support and organization are mainly provided by ______ because they regulate the interstitial fluid.
The brain's ventricles and the spinal cord's central canal are lined with ______, which aids in producing and circulating cerebrospinal fluid.
The brain's ventricles and the spinal cord's central canal are lined with ______, which aids in producing and circulating cerebrospinal fluid.
While both myelinated and unmyelinated nerve fibers rely on Schwann cells, only myelinated fibers benefit from multiple wrapping that forms a ______, increasing the speed of signal transmission.
While both myelinated and unmyelinated nerve fibers rely on Schwann cells, only myelinated fibers benefit from multiple wrapping that forms a ______, increasing the speed of signal transmission.
Damage to the cerebellum can be assessed by analyzing the cells in the ______ layer because the layer is the output neurons integrating cerebellar cortical computation.
Damage to the cerebellum can be assessed by analyzing the cells in the ______ layer because the layer is the output neurons integrating cerebellar cortical computation.
In the cerebral cortex, the multiform layer, also known as the polymorphic layer, is characterized by diverse cell types and is located next to the ______.
In the cerebral cortex, the multiform layer, also known as the polymorphic layer, is characterized by diverse cell types and is located next to the ______.
Unlike the cerebrum which has a less defined organization, the ______ contains granule cells for processing information.
Unlike the cerebrum which has a less defined organization, the ______ contains granule cells for processing information.
The irregular connective tissue that is continuous with the periosteum of the skull is the ______ which provides critical protection for the brain.
The irregular connective tissue that is continuous with the periosteum of the skull is the ______ which provides critical protection for the brain.
The ______ is responsible for engulfing infectious agents and harmful substances to protect the CNS.
The ______ is responsible for engulfing infectious agents and harmful substances to protect the CNS.
A key distinction between the white and gray matter in the central nervous system is that white matter primarily consists of myelinated nerve fibers, while gray matter is characterized by ______.
A key distinction between the white and gray matter in the central nervous system is that white matter primarily consists of myelinated nerve fibers, while gray matter is characterized by ______.
The dorsal horns of the spinal cord gray matter contain interneurons which are responsible for receiving inputs from sensory fibers, while the ventral horns contain ______ motor neurons.
The dorsal horns of the spinal cord gray matter contain interneurons which are responsible for receiving inputs from sensory fibers, while the ventral horns contain ______ motor neurons.
Satellite cells in the peripheral nervous system perform similar support functions to astrocytes in the central nervous system, primarily by regulating the microenvironment and electrically ______ PNS cell bodies.
Satellite cells in the peripheral nervous system perform similar support functions to astrocytes in the central nervous system, primarily by regulating the microenvironment and electrically ______ PNS cell bodies.
Because Schwann cells insulate and myelinate axons, they permit faster action potential propagation along axons in the ______.
Because Schwann cells insulate and myelinate axons, they permit faster action potential propagation along axons in the ______.
In the peripheral nervous system, individual nerve fibers are surrounded by the ______, a layer of connective tissue that supports and insulates the axon.
In the peripheral nervous system, individual nerve fibers are surrounded by the ______, a layer of connective tissue that supports and insulates the axon.
While myelinated nerve fibers are insulated by a myelin sheath to prevent signal loss and are characterized by nodes of Ranvier, unmyelinated fibers lack such sheaths and have ______ axons.
While myelinated nerve fibers are insulated by a myelin sheath to prevent signal loss and are characterized by nodes of Ranvier, unmyelinated fibers lack such sheaths and have ______ axons.
A neuron characterized by a single axon and multiple dendrites is classified as a ______ neuron.
A neuron characterized by a single axon and multiple dendrites is classified as a ______ neuron.
Structures such as Nissl bodies which are similar to rough endoplasmic reticulum are equivalent to rough endoplasmic reticulum in neurons, and are involved in ______ synthesis.
Structures such as Nissl bodies which are similar to rough endoplasmic reticulum are equivalent to rough endoplasmic reticulum in neurons, and are involved in ______ synthesis.
Unlike a nucleus, which is a cluster of neuron cell bodies within the central nervous system, a ______ is a cluster of neuron cell bodies in the peripheral nervous system.
Unlike a nucleus, which is a cluster of neuron cell bodies within the central nervous system, a ______ is a cluster of neuron cell bodies in the peripheral nervous system.
Three layers of meninges protecting the CNS by limiting infection include the dura mater, the arachnoid mater, and the ______.
Three layers of meninges protecting the CNS by limiting infection include the dura mater, the arachnoid mater, and the ______.
In contrast to the outer region of the spinal cord, the outer region of the brain primarily consists of blank matter which allows for protection.
In contrast to the outer region of the spinal cord, the outer region of the brain primarily consists of blank matter which allows for protection.
Nervous tissue is derived from the ectoderm, which is the primary ______ layer of the embryo.
Nervous tissue is derived from the ectoderm, which is the primary ______ layer of the embryo.
While peripheral nerves rely on epineurium, perineurium, and endoneurium for structural integrity, central nervous system tracts lack these distinct connective tissue layers and instead rely on ______.
While peripheral nerves rely on epineurium, perineurium, and endoneurium for structural integrity, central nervous system tracts lack these distinct connective tissue layers and instead rely on ______.
In contrast to spinal ganglia, autonomic ganglia are characterized by processes that dictate specific responses in smooth muscle, cardiac muscle, of glands involving ______ neurons.
In contrast to spinal ganglia, autonomic ganglia are characterized by processes that dictate specific responses in smooth muscle, cardiac muscle, of glands involving ______ neurons.
The functional unit of nervous tissue, responsible for transmitting electrical and chemical signals, is the ______.
The functional unit of nervous tissue, responsible for transmitting electrical and chemical signals, is the ______.
Flashcards
What is a Neuron?
What is a Neuron?
A nerve cell that transmits electrical signals.
What is the Cell Body (Soma)?
What is the Cell Body (Soma)?
The main part of a neuron, containing the nucleus.
What are Dendrites?
What are Dendrites?
Branch-like extensions of a neuron that receive signals.
What is an Axon?
What is an Axon?
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What is the Axon Hillock?
What is the Axon Hillock?
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What is Nissl Substance?
What is Nissl Substance?
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What is a Synapse?
What is a Synapse?
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What are Multipolar Neurons?
What are Multipolar Neurons?
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What are Bipolar Neurons?
What are Bipolar Neurons?
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What are Unipolar Neurons?
What are Unipolar Neurons?
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What are Anaxonic Neurons?
What are Anaxonic Neurons?
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What are Glial Cells?
What are Glial Cells?
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What are Astrocytes?
What are Astrocytes?
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What are Oligodendrocytes?
What are Oligodendrocytes?
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What are Microglia?
What are Microglia?
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What are Ependymal Cells?
What are Ependymal Cells?
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What are Meninges?
What are Meninges?
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What is the Dura Mater?
What is the Dura Mater?
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What is the Arachnoid Mater?
What is the Arachnoid Mater?
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What is the Pia Mater?
What is the Pia Mater?
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What is White Matter?
What is White Matter?
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What is Gray Matter?
What is Gray Matter?
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What is the Cerebrum?
What is the Cerebrum?
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What is the Cerebral Cortex?
What is the Cerebral Cortex?
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What is the Cerebral Cortex Layers?
What is the Cerebral Cortex Layers?
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What is the Cerebellum?
What is the Cerebellum?
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What is the Cerebellar Cortex?
What is the Cerebellar Cortex?
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What are Dorsal & Ventral Horns?
What are Dorsal & Ventral Horns?
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What are Dorsal Horns?
What are Dorsal Horns?
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What are Ventral Horns?
What are Ventral Horns?
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What is the Perineurium?
What is the Perineurium?
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What is the Endoneurium?
What is the Endoneurium?
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What is the Epineurium?
What is the Epineurium?
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What are Schwann Cells?
What are Schwann Cells?
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What are Satellite Cells?
What are Satellite Cells?
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What are Myelinated Nerve Fibers?
What are Myelinated Nerve Fibers?
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What are Unmyelinated Nerve Fibers?
What are Unmyelinated Nerve Fibers?
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Study Notes
- Histology of the nervous system covers nervous tissue of the central and peripheral nervous systems.
Prayer
- The provided is a prayer for illumination, wisdom, understanding, memory, and clarity in study.
- It asks for guidance in work from start to completion, through Christ.
Topic Outline
- Nervous tissue overview
- Central nervous system focus
- Peripheral nervous system focus
- Laboratory activities/review
Learning Outcomes
- Differentiate neuron types by structure.
- Identify neuroglial cells in CNS and PNS.
- Distinguish regions of the brain/spinal cord by location and structure.
- Identify cerebellar histologic layers.
- Differentiate myelinated/unmyelinated nerve fibers microscopically.
Neuron Morphology
- Neurons come in a variety of forms
- Important aspects include cell body, axon, and dendrites,
Cells of the Nervous Tissue: Neurons
- Neurons can be classified into structural classes
- Multipolar neurons have multiple dendrites and one axon
- Bipolar neurons have a single dendrite and an axon
- Unipolar neurons have a peripheral and central process and one axon
- Anaxonic neurons have no axon
Neuron Classification
- Neurons are classified as
- Pseudounipolar
- Unipolar
- Bipolar
- Multipolar
Synapse
- Synapses are where neurons communicate
Central Nervous System
Glial Cells of the CNS
- Includes astrocytes, oligodendrocytes, microglia, and ependymal cells
- Astrocytes form the blood-brain barrier, regulate fluid, and support the CNS
- Oligodendrocytes myelinate CNS axons for faster action potential propagation
- Microglia are phagocytic cells protecting the CNS by engulfing harmful substances
- Ependymal cells line brain ventricles/spinal cord, aiding CSF production/circulation
Connective Tissue of the CNS
- The CNS has meningeal layers
- Dura mater is the outermost layer
- It has thick, dense connective tissue
- It is continuous with the periosteum of the skull
- Arachnoid mater is the middle layer
- It has two components, a sheet of connective tissue and trabeculae
- The trabeculae are loosely arranged and continuous with the pia mater
- Pia mater is the innermost layer comprised of flattened mesenchymal-derived cells
CNS Structures
- White matter consists mainly of myelinated nerve fibers, with some unmyelinated fibers and glial cells
- Gray matter is mainly neuronal cell bodies, unmyelinated fibers, and neuroglial cells.
Cerebrum
- Study of the cerebrum
Cerebral Cortex
- Examination of the cerebral cortex
Layers of the Cerebral Cortex
- Mnemonic to remember the layers = "Many Exes who Got Poisoned Inside GIT Promised to Move on"
- The layers are:
- Molecular layer
- External granular layer
- External pyramidal layer
- Internal granular layer
- Internal pyramidal layer
- Multiform layer
Cerebellum
- Study of the cerebellum
Spinal Cord
- Gray matter is H-shaped and contains dorsal and ventral horns
- Dorsal horns contain interneurons, receiving sensory fibers from spinal cord neurons
- Ventral horns contain multipolar motor neurons.
- White matter is peripherally located
- It is made up of ascending and descending, mostly myelinated, fibers
Review Activities
-
Germ layer for nervous tissue origin
-
Brain's outer region vs. spinal cord's inner region
-
Nervous tissue phagocyte
-
Functional unit of nervous tissue
-
Rough endoplasmic reticulum equivalents
-
Neuron with single axon, multiple dendrites
-
Lipoidal substance covering nerve fibers in CNS and PNS
Microscopic Features
- Study the distinguishing features of neurons
Histologic Differences
- Review histologic differences between gray matter in the cerebrum and cerebellum
Peripheral Nervous System
- Focus on the peripheral nervous system
Components of the PNS
- Nerves
- Ganglia
- Nerve endings
Glial Cells
- Astrocytes
- Oligodendrocytes
- Microglia
- Ependymal cells
- Schwann cells
- Satellite cells
PNS Neuroglia
- Schwann cells
- Satellite cells
Connective Tissue of the Peripheral Nervous System
- Epineurium: This is the external coat of a nerve.
- Perineurium: This surrounds each bundle of nerve fibers.
- Endoneurium: This surrounds individual nerve fibers.
Peripheral Nervous System
- Focus on the peripheral nervous system
Ganglion
- Focus on the ganglion structure
Myelinated Nerve Fibers
- Have a myelin sheath
- This feature prevents loss of nerve impulse
- Nodes of ranvier
- Internodal segments or schwann segments
Peripheral Nerve
- Focus on the peripheral nerve
Unmyelinated Nerve Fibers
- Naked axons
- There is no multiple wrapping to form a myelin sheath
- Smaller diameter axons
- Still has schwann cells
- Nodes of Ranvier are not seen
Lab Activities / Review
- Study to differentiate a nerve from a tract and a nucleus from a ganglion
- Study how to differentiate spinal and autonomic ganglia
Preparation for next session:
- Connective tissue and blood smear prep for labs
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