Histology of Epithelial Tissue
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Questions and Answers

What characterizes pseudostratified columnar epithelium?

  • It has a flat shape with no distinct layers.
  • All cells are undifferentiated and identical in shape.
  • It consists of multiple layers of cells.
  • Nuclei are located at various levels within a single layer. (correct)
  • Which modification is characterized by extensions of the free (apical) surface that increase surface area?

  • Stereocilia
  • Cilia
  • Microvilli (correct)
  • Basal bodies
  • What is a distinctive feature of transitional epithelium?

  • All cells are ciliated and actively transport substances.
  • It has a single layer of cells with uniform shape.
  • It includes dome-shaped and bi-nucleate cells. (correct)
  • It consists solely of flat cells.
  • Where is pseudostratified ciliated columnar epithelium typically found?

    <p>In the respiratory tract. (A)</p> Signup and view all the answers

    What happens to the cells in transitional epithelium as the bladder fills?

    <p>They flatten, reducing from 5-6 to 2-3 layers. (C)</p> Signup and view all the answers

    What is the primary function of cilia in the respiratory tract and fallopian tube?

    <p>To move fluid in a coordinated manner (C)</p> Signup and view all the answers

    What is the structure of the core of cilia known as?

    <p>Axoneme (B)</p> Signup and view all the answers

    Which cellular structure is characterized as having a rigid apical area and is found only in the urinary tract?

    <p>Membrane plaques (A)</p> Signup and view all the answers

    What role does glycocalyx serve in the cellular environment?

    <p>Participating in cell recognition and adhesion (B)</p> Signup and view all the answers

    What process describes the transformation of stratified squamous epithelial cells as they migrate towards the surface?

    <p>Keratinization (C)</p> Signup and view all the answers

    What do lamellar bodies primarily provide in keratinization?

    <p>Extracellular membrane sheets (A)</p> Signup and view all the answers

    Which protein is primarily associated with the keratinization process?

    <p>Cytokeratin (C)</p> Signup and view all the answers

    What initiates the movement of microtubules within cilia according to the sliding microtubule hypothesis?

    <p>Dynein activation (D)</p> Signup and view all the answers

    What is the primary function of simple cuboidal epithelium?

    <p>Produce hormones and enzymes (D)</p> Signup and view all the answers

    Which type of epithelium is specialized for lining the heart and blood vessels?

    <p>Endothelium (D)</p> Signup and view all the answers

    Where is simple columnar epithelium commonly found?

    <p>Lining of the GI tract (A)</p> Signup and view all the answers

    What characteristic defines the nuclei of simple cuboidal epithelial cells?

    <p>Spherical and centrally placed (D)</p> Signup and view all the answers

    Which layer is the deepest in the stratified squamous epithelium?

    <p>Stratum basale (C)</p> Signup and view all the answers

    What is the primary role of stratified squamous epithelium?

    <p>Protection against abrasion (A)</p> Signup and view all the answers

    Which type of epithelium is characterized by having nuclei that are oval and located at the basal region of the cells?

    <p>Simple columnar (B)</p> Signup and view all the answers

    What distinguishes stratified cuboidal epithelium from other types of epithelial tissue?

    <p>It is rare and forms large ducts in certain glands. (D)</p> Signup and view all the answers

    What is a primary characteristic of epithelial tissue?

    <p>Continuous sheets of cells (B)</p> Signup and view all the answers

    Which function is NOT associated with epithelial tissue?

    <p>Movement (C)</p> Signup and view all the answers

    What describes the vascularity of epithelial tissue?

    <p>Avascular, relying on diffusion from underlying connective tissue (A)</p> Signup and view all the answers

    What term refers to cells lining cardiovascular and lymph passageways?

    <p>Endothelium (A)</p> Signup and view all the answers

    What is the main function of the basal lamina in epithelial tissue?

    <p>Providing support to epithelial cells (A)</p> Signup and view all the answers

    Which nutrient plays a significant role in maintaining healthy epithelial tissue?

    <p>Zinc (C)</p> Signup and view all the answers

    Which of the following is a characteristic of the extracellular matrix in epithelial tissue?

    <p>Minimal presence in epithelial tissue (B)</p> Signup and view all the answers

    What do intercellular junctions in epithelial tissue primarily facilitate?

    <p>Electrical signal and molecule transfer (B)</p> Signup and view all the answers

    Which example is associated with a potential problem in epithelial tissue?

    <p>Melanoma (C)</p> Signup and view all the answers

    Which of these correctly describes the polarity of epithelial cells?

    <p>Have specialized regions with apical and basal surfaces (B)</p> Signup and view all the answers

    What type of epithelial cells are characterized by a large amount of rough endoplasmic reticulum at the base and granules at the apical pole?

    <p>Protein secreting epithelial cells (B)</p> Signup and view all the answers

    Which type of epithelium is responsible for forming hormones without the use of ducts?

    <p>Endocrine glands (C)</p> Signup and view all the answers

    Which of the following locations is NOT primarily associated with steroid hormone secreting epithelial cells?

    <p>Kidney tubules (C)</p> Signup and view all the answers

    Mucin secreting epithelial cells perform which of the following functions?

    <p>Providing lubrication in the mouth (A)</p> Signup and view all the answers

    What mechanism do exocrine glands use to secrete products?

    <p>Pinching off of vesicles from the apical cytoplasm (B)</p> Signup and view all the answers

    Which of the following statements about ion pumping epithelial cells is incorrect?

    <p>They are primarily found in sebaceous glands. (A)</p> Signup and view all the answers

    What is the main function of sebaceous glands in the skin?

    <p>Producing oily lipids for lubrication (A)</p> Signup and view all the answers

    Which type of secretion involves the entire cell being discharged into the duct?

    <p>Holocrine (C)</p> Signup and view all the answers

    Which type of sweat gland is primarily responsible for thermoregulation and excretion?

    <p>Merocrine glands (B)</p> Signup and view all the answers

    What distinguishes apocrine sweat glands from merocrine sweat glands?

    <p>They are located in the axillae and groin. (D)</p> Signup and view all the answers

    Which condition is characterized by an abnormal thickening of the stratum spinosum in the epidermis?

    <p>Acanthosis (D)</p> Signup and view all the answers

    Which structure is classified as the only unicellular exocrine gland?

    <p>Goblet cell (D)</p> Signup and view all the answers

    Which condition is associated with hyperkeratosis and thickening of the granular layer accompanied by destruction of basal cells?

    <p>Lichen planus (C)</p> Signup and view all the answers

    What is the primary product of ceruminous glands?

    <p>Ear wax (D)</p> Signup and view all the answers

    Which skin condition is most commonly referred to as moles?

    <p>Naevi (A)</p> Signup and view all the answers

    Which statement regarding sweat glands is incorrect?

    <p>Merocrine glands are activated by hormones. (A)</p> Signup and view all the answers

    Study Notes

    Epithelial Tissue Characteristics & Classification

    • Cells cannot function independently; they are aggregated into tissues with similar functions.
    • Tissues aggregate into organs, formed by different tissue arrangements.
    • Tissues, through their cells and intercellular material, perform vital bodily functions.
    • Tissues communicate via intercellular junctions, transmitting electrical signals and small molecules.
    • Tissues maintain structural integrity through complex extracellular matrices and cell junctions.
    • Epithelial tissues display great variation in extracellular matrix and junction structures between different tissue types.
    • Epithelial tissues are made of tightly bound cells with little extracellular matrix.

    Types of Tissue

    • Epithelium: Covers body surfaces, lines cavities, or forms glands.
    • Connective tissue: Supports and connects other tissues.
    • Muscle tissue: Enables movement.
    • Nervous tissue: Controls and coordinates bodily functions.

    Epithelial Tissue Characteristics (Continued)

    • Epithelial tissue is composed of layers of cells.
    • Polarity: Specialized apical and basal surfaces.
    • Supported by connective tissue (basal lamina is part of basement membrane).
    • Avascular but innervated.

    Functions of Epithelial Cells

    • Absorption: Absorbing nutrients.
    • Transport: Moving ions.
    • Digestion: Secreting enzymes.
    • Secretion: Excreting substances.
    • Barrier: Protecting against environmental factors.
    • Sensory reception: Detecting stimuli (smell, taste, etc.).
    • Filtration: Filtering fluids.
    • Reproduction: Producing gametes.

    Potential Problems in Epithelial Tissue

    • Acne
    • Dermatitis
    • Obesity
    • Psoriasis
    • Scabies
    • Shingles (Herpes Zoster)
    • Melanoma (skin cancer)

    General Classification of Epithelial Tissue

    • Classified based on cell shape and arrangement (presence of layers).
    • Simple squamous: Single layer of flat cells; lines lungs, blood vessels, body cavities.
    • Simple cuboidal: Single layer of cube-shaped cells; lines kidney tubules, ducts.
    • Simple columnar: Single layer of column-shaped cells; lines gut, oviduct, stomach, intestines.
    • Stratified squamous: Multiple layers of flat cells; found in outer skin, mouth, etc. High protection.
    • Stratified cuboidal: Multiple layers of cube-shaped cells; less common, found in sweat glands.
    • Stratified columnar: Multiple layers of column-shaped cells; less common, found in some ducts.
    • Pseudostratified columnar: Single layer with variable cell heights; often ciliated; lines respiratory tract, makes mucus.

    Free Surface Modifications

    • Microvilli: Increase surface area; found in absorptive cells (intestines, kidneys).
    • Stereocilia: Extremely long microvilli; enhance surface area; found in epididymis and inner ear hair cells.
    • Cilia: Hair-like extensions; facilitate movement; found in respiratory and fallopian tubes.
    • Flagellum: Long cilium; present in sperm cells; facilitates motility.
    • Membrane plaques: Stiff structures; facilitate cell motility; in urinary tract cells.

    Keratinization

    • Stratified squamous epithelium; keratin fills cells as they migrate upward.
    • Creates waterproof, tough layer.
    • Keratin forms protective layers

    Secretory Adaptations

    • Many epithelial cells serve as glands specialized for secretion.
    • Endocrine glands: Secrete hormones directly into the bloodstream (no ducts).
    • Exocrine glands: Secrete products into ducts that lead to body surfaces or cavities
    • Protein-secreting cells have abundant rough endoplasmic reticulum and secretory granules.
    • Mucin-secreting cells manufacture mucins (glycoproteins and proteoglycans), leading to various roles, lubricants or barriers.
    • Steroid-hormone-secreting cells contain abundant smooth endoplasmic reticulum, for the synthesis of steroids.
    • Ion-transporting cells; increase surface area via folding or other mechanisms, to pump ions, facilitate active transport.

    Gland Types

    • Sebaceous glands: Associated with hair follicles; secrete sebum.
    • Sweat glands: Excrete sweat (apocrine and merocrine types).
    • Apocrine glands: Secrete a thick fluid containing lipids; located primarily in axillae, groin, etc.
    • Holocrine glands: Entire cell disintegrates to release secretions; found in sebaceous glands.

    Clinical Considerations

    • (Hyperkeratosis, Parakeratosis, Acanthosis, Naevi, Dermatitis)

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    Description

    Test your knowledge on the characteristics and functions of different types of epithelial tissues, including pseudostratified columnar and transitional epithelium. This quiz covers features, modifications, and typical locations of these tissues in the human body.

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