Histology: Cartilage Types and Characteristics

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20 Questions

What is the function of perichondrium?

To supply cartilage with nutrition from its blood vessels by diffusion

Which type of cartilage is translucent grey blue in fresh state?

Hyaline cartilage

In which part of the body can elastic cartilage be found?

Respiratory passages; nose, larynx, trachea, and bronchi

Where is hyaline cartilage commonly found?

Costal cartilage of thoracic cage

What is the function of chondroblasts in hyaline cartilage?

Producing extracellular matrix and fibers for appositional growth

Where are chondroblasts located in hyaline cartilage?

Inner layer of perichondrium

What is the matrix of cartilage like?

Firm (rigid, rubbery) matrix

What is the primary function of chondrocytes in hyaline cartilage?

Produce and maintain extracellular matrix and type II collagen fibers

Why are the fibers in the hyaline cartilage not observed by light microscopes?

They have the same refractive index as the matrix

What is the main component of hyaline cartilage matrix?

Ground substance

What is the primary function of chondrocytes in cartilage?

Secreting the extracellular matrix components

Where are chondrogenic cells primarily located in cartilage?

Perichondrium

Why is hyaline cartilage considered avascular?

Due to the absence of blood vessels within the cartilage itself

Which type of cartilage is commonly found in the respiratory passages and trachea?

Hyaline cartilage

What is the main function of the perichondrium?

Providing an attachment for muscles and ligaments

What is the primary function of chondroblasts in hyaline cartilage?

Synthesize extracellular matrix including type I, II collagen, and elastic fibers

Where are stellate or spindle shaped primitive mesenchymal cells (chondrogenic cells) located during chondrogenesis?

Inside the inner cellular layer of perichondrium

What is the function of chondrocytes in hyaline cartilage?

Produce and maintain extracellular matrix and type II collagen fibers

Where are chondroblasts located in hyaline cartilage?

Inside the inner cellular layer of perichondrium

What is the main component of hyaline cartilage matrix?

Ground substance between chondrocytes

Study Notes

Cartilage Structure and Function

  • Perichondrium functions as a nutritive layer that supplies cartilage with oxygen and nutrients.

Types of Cartilage

  • Elastic cartilage is found in the external ear and the auditory tube.

Hyaline Cartilage

  • Hyaline cartilage is translucent grey-blue in its fresh state.
  • Hyaline cartilage is commonly found in the respiratory passages, trachea, bronchi, and in the articular cartilage of joints.
  • Chondroblasts in hyaline cartilage produce the cartilage matrix and are located in the perichondrium.
  • Chondrocytes are mature cartilage cells located within the cartilage matrix, and their primary function is to maintain the matrix.
  • The matrix of hyaline cartilage is composed of a gel-like substance with sparse, fine collagen type II fibers that are not visible under a light microscope.
  • The main component of hyaline cartilage matrix is chondroitin sulfate.

Chondrocytes and Chondroblasts

  • Chondrocytes are responsible for maintaining the cartilage matrix, responding to growth factors, and producing matrix components.
  • Chondrogenic cells, also known as stellate or spindle-shaped primitive mesenchymal cells, are located in the perichondrium during chondrogenesis and differentiate into chondroblasts.
  • Chondroblasts are located in the perichondrium and are responsible for producing the cartilage matrix.

Vascularization

  • Hyaline cartilage is considered avascular because it lacks a direct blood supply, relying on diffusion from surrounding tissues.

Learn about the specialized form of dense connective tissue known as cartilage, its firm matrix, and its poor blood supply. Explore the types of cartilage, including hyaline, elastic, and white fibrocartilage.

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