5 Questions
Which histamine receptor is important in producing smooth muscle contraction and increasing capillary permeability?
H1 receptor
What is the effect of histamine on small blood vessels?
Vasodilation
Which pathological processes are mediated by histamine H1 receptors?
Allergic rhinitis
What does histamine stimulate in the stomach?
Parietal cells
Which histamine receptor is the target of clinically useful drugs?
H2 receptor
Study Notes
Histamine Receptors and Effects
- Histamine H1 receptors are important in producing smooth muscle contraction and increasing capillary permeability.
- Histamine causes vasodilation of small blood vessels, leading to increased blood flow and decreased blood pressure.
- Histamine H1 receptors mediate various pathological processes, including allergic responses, anaphylaxis, and itching.
- Histamine stimulates gastric acid secretion in the stomach, leading to increased digestive enzyme production.
- H2 receptors are the target of clinically useful drugs, such as ranitidine, which are used to treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers.
Test your knowledge of histamine receptors and their pharmacologic effects in this quiz. Explore the roles of H1 and H2 receptors, and learn about the clinical implications of histamine binding.
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