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Histamine and Its Metabolism

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Questions and Answers

What is histamine formed from?

The amino acid histidine (correct)

The amino acid tryptophan

The amino acid tyrosine

The amino acid glycine

What enzymes metabolize histamine in the body?

Acetylcholine esterase and laminin

Trypsin and chymotrypsin

Histidine decarboxylase and peptidase

Monoamine oxidase and diamine oxidase (correct)

What is the major metabolite of histamine that can be measured in the urine?

Diamine oxidase

Histamine itself

Imidazole acetic acid (correct)

Monoamine oxidase

What is the role of histamine in the stomach?

To increase stomach acid secretion Signup and view all the answers

What is histamine released from in response to IgE-mediated allergic reactions?

Mast cells and enterochromaffin cells Signup and view all the answers

What is the primary mechanism by which the Lewis triple response is mediated?

Through H1 and H2 receptors Signup and view all the answers

What is the characteristic feature of the center of an intradermal injection of histamine?

A small red spot Signup and view all the answers

What is the order of the characteristics of the Lewis triple response?

Small red spot, edematous wheal, red flare Signup and view all the answers

How many receptors for histamine have been identified?

4 Signup and view all the answers

What is the term for the characteristic response to an intradermal injection of histamine?

Lewis triple response Signup and view all the answers