Histamine and Its Metabolism

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Questions and Answers

What is histamine formed from?

  • The amino acid histidine (correct)
  • The amino acid tryptophan
  • The amino acid tyrosine
  • The amino acid glycine

What enzymes metabolize histamine in the body?

  • Acetylcholine esterase and laminin
  • Trypsin and chymotrypsin
  • Histidine decarboxylase and peptidase
  • Monoamine oxidase and diamine oxidase (correct)

What is the major metabolite of histamine that can be measured in the urine?

  • Diamine oxidase
  • Histamine itself
  • Imidazole acetic acid (correct)
  • Monoamine oxidase

What is the role of histamine in the stomach?

<p>To increase stomach acid secretion (D)</p> Signup and view all the answers

What is histamine released from in response to IgE-mediated allergic reactions?

<p>Mast cells and enterochromaffin cells (A)</p> Signup and view all the answers

What is the primary mechanism by which the Lewis triple response is mediated?

<p>Through H1 and H2 receptors (C)</p> Signup and view all the answers

What is the characteristic feature of the center of an intradermal injection of histamine?

<p>A small red spot (B)</p> Signup and view all the answers

What is the order of the characteristics of the Lewis triple response?

<p>Small red spot, edematous wheal, red flare (B)</p> Signup and view all the answers

How many receptors for histamine have been identified?

<p>4 (D)</p> Signup and view all the answers

What is the term for the characteristic response to an intradermal injection of histamine?

<p>Lewis triple response (C)</p> Signup and view all the answers

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