10 Questions
What is histamine formed from?
The amino acid histidine
What enzymes metabolize histamine in the body?
Monoamine oxidase and diamine oxidase
What is the major metabolite of histamine that can be measured in the urine?
Imidazole acetic acid
What is the role of histamine in the stomach?
To increase stomach acid secretion
What is histamine released from in response to IgE-mediated allergic reactions?
Mast cells and enterochromaffin cells
What is the primary mechanism by which the Lewis triple response is mediated?
Through H1 and H2 receptors
What is the characteristic feature of the center of an intradermal injection of histamine?
A small red spot
What is the order of the characteristics of the Lewis triple response?
Small red spot, edematous wheal, red flare
How many receptors for histamine have been identified?
4
What is the term for the characteristic response to an intradermal injection of histamine?
Lewis triple response
This quiz covers the biosynthesis, storage, and metabolism of histamine, a neurotransmitter involved in various physiological processes. Learn about the enzymes involved in histamine metabolism and how excess production can be detected. Discover the role of histamine in the body, particularly in response to IgE-mediated reactions.
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