Hirschsprung Disease

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Questions and Answers

Which part of the colon is most commonly affected in Hirschsprung disease?

  • Transverse colon
  • Descending colon
  • Rectosigmoid region (correct)
  • Ascending colon

What is the first sign of Hirschsprung disease in newborns?

  • Failure to pass meconium within 48 hours (correct)
  • Gastrointestinal obstruction
  • Bilious vomiting
  • Abdominal distention

Which part of the colon can be affected in total colonic Hirschsprung disease?

  • Ascending colon
  • Rectosigmoid region
  • Entire colon (correct)
  • Transverse colon

What is the medical term for Hirschsprung disease?

<p>Congenital aganglionic megacolon (C)</p> Signup and view all the answers

Which type of Hirschsprung disease is associated with an early and more severe onset of symptoms?

<p>Long segment (C)</p> Signup and view all the answers

Which of the following is a characteristic of Hirschsprung disease?

<p>It is a genetic disorder. (A)</p> Signup and view all the answers

What is the main symptom of Hirschsprung disease in newborns?

<p>Constipation (D)</p> Signup and view all the answers

Which part of the colon is most commonly affected in Hirschsprung disease?

<p>Rectosigmoid region (A)</p> Signup and view all the answers

What type of Hirschsprung disease can affect the entire colon?

<p>Total colonic HD (D)</p> Signup and view all the answers

What is the association between the length of the aganglionic segment and the onset of symptoms in Hirschsprung disease?

<p>A longer aganglionic segment is associated with an early and more severe onset of symptoms. (A)</p> Signup and view all the answers

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Study Notes

Hirschsprung Disease

  • The rectosigmoid region of the colon is most commonly affected in Hirschsprung disease.

Clinical Presentation

  • The first sign of Hirschsprung disease in newborns is often a failure to pass meconium in the first 24-48 hours after birth.

Total Colonic Hirschsprung Disease

  • In total colonic Hirschsprung disease, the entire colon can be affected.

Medical Terminology

  • Hirschsprung disease is also known as congenital aganglionic megacolon.

Types of Hirschsprung Disease

  • The long-segment subtype of Hirschsprung disease is associated with an early and more severe onset of symptoms.

Characteristics

  • A characteristic of Hirschsprung disease is the absence of ganglion cells in the myenteric plexus of the intestinal wall.

Symptoms

  • The main symptom of Hirschsprung disease in newborns is a delay in passing meconium.

Pathophysiology

  • The length of the aganglionic segment is directly correlated with the onset of symptoms in Hirschsprung disease, with longer segments associated with earlier and more severe symptoms.

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