High Sensitivity C-Reactive Protein (hsCRP) in Cardiovascular Disease

Mengapa pengukuran tingkat hsCRP penting untuk menilai risiko penyakit kardiovaskular?

Apa itu hsCRP dan dimana protein ini diproduksi?

Berapa rentang nilai rata-rata hsCRP yang diamati pada populasi India?

Berapa nilai hsCRP yang berbeda diamati pada pasien dengan penyakit kardiovaskular yang sudah terdiagnosis?

Berapa jumlah studi yang fokus pada tingkat hsCRP pada pasien dengan sindrom metabolik?

Apa saja akhir dari penelitian yang menunjukkan hubungan antara hsCRP dan penyakit arteri koroner?

Berapa jumlah studi yang mengevaluasi korelasi antara tingkat hsCRP dengan adipositas abdominal dan BMI?

Apakah salah satu dari studi tersebut mengevaluasi sensitivitas, spesifisitas, nilai prediksi positif, dan negatif dari hsCRP dalam prediksi CAR?

Apa yang disarankan oleh studi terbaru terkait hsCRP sebagai penanda individu tanpa faktor risiko yang jelas yang mungkin berisiko terkena penyakit jantung?

High Sensitivity C-Reactive Protein (hsCRP)

High sensitivity C-reactive protein (hsCRP) is a protein produced in the liver and serves as a general inflammatory marker. Measuring hsCRP levels can be beneficial for assessing the risk of developing cardiovascular disease (CVD).

Coronary Artery Disease (CAD)

Studies have shown that hsCRP is an independent predictor of diverse end points, including coronary artery disease (CAD). High hsCRP levels have been observed in Indian populations, with mean values ranging from 1.0 to 2.9 mg/L (median, 1.88 mg/L) in control groups. Among patients with established CVD, hsCRP values varied widely, from 2.46 to 9.3 mg/L.

Metabolic Syndrome

Nine of the studies (37.5%) included in the review focused on hsCRP levels in patients with metabolic syndrome, including diabetes.

Abdominal Adiposity and Body Mass Index (BMI)

Six of the studies (25%) assessed the correlation between hsCRP levels and abdominal adiposity and BMI.

Predictive Value

None of the studies evaluated the sensitivity, specificity, positive and negative predictive values of hsCRP in CAR prediction.

Determining Chances of Developing CVD

Recent studies suggest that hsCRP could be a marker for individuals without apparent risk factors who may be at risk of developing heart disease. Elevated hsCRP levels (1.0 mg/L) have been linked to an increased risk of stroke, sudden cardiac death, and peripheral arterial disease, even among individuals with cholesterol levels within an acceptable range.

Test Measurement

The hsCRP test measures CRP levels in the blood and helps determine the risk of developing CVD.

Explore the significance of high sensitivity C-reactive protein (hsCRP) levels in assessing the risk of developing cardiovascular disease (CVD), including coronary artery disease (CAD) and metabolic syndrome. Learn about the correlation between hsCRP levels, abdominal adiposity, and body mass index (BMI), as well as the predictive value of hsCRP in determining the chances of developing CVD.