Hershey–Chase Experiment Quiz
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Questions and Answers

What is the T2 virus?

  • A bacterium
  • A component of DNA
  • A bacteriophage that infects Escherichia coli (correct)
  • A type of protein

How does a phage reproduce?

  • By transforming into a protein structure
  • By injecting its DNA into the bacterial cell (correct)
  • By breaking down the bacterial cell's wall
  • By attaching to the bacterial cell's outer wall

Why did biologists conduct the Hershey-Chase experiment?

  • To study the structure of phage proteins
  • To investigate the components of a bacterium
  • To understand the process of phage reproduction (correct)
  • To determine how phages attach to a bacterial cell

What was the composition of the T2 phage in terms of protein and nucleic acid?

<p>50% protein, 50% nucleic acid (B)</p> Signup and view all the answers

How do progeny phages emerge from a cell after infection?

<p>They escape by breaking open the cell (C)</p> Signup and view all the answers

What role did radioactive isotopes play in the Hershey-Chase experiment?

<p>Tracking the fate of phosphorus and sulfur in protein and DNA (A)</p> Signup and view all the answers

What did Oswald Avery, Colin MacLeod, and Maclyn McCarty isolate and purify successfully in 1944?

<p>DNA (B)</p> Signup and view all the answers

Which type of enzymes were ineffective against the transforming substance identified by Avery, MacLeod, and McCarty?

<p>Ribonuclease (D)</p> Signup and view all the answers

What did Griffith theorize might be responsible for the transformation of the R-strain bacteria?

<p>Polysaccharide coat of the dead bacteria (B)</p> Signup and view all the answers

Which type of bacteria had mutated to the virulent S form according to one of Griffith's interpretations?

<p>Type IIR (C), Type IIR (D)</p> Signup and view all the answers

Which enzymes had an effect on eliminating the biological activity of the transforming substance?

<p>DNAse (A)</p> Signup and view all the answers

What did Griffith conclude was the reason behind the transformation of R-strain bacteria?

<p>Acquiring genetic virulence of the dead S-strain bacteria (A)</p> Signup and view all the answers

What did Griffith observe when he injected living S-strain bacteria into mice?

<p>The mice developed pneumonia and died. (D)</p> Signup and view all the answers

What was the result when Griffith injected R-strain bacteria into mice?

<p>The mice lived, and no bacteria were found in their blood. (A)</p> Signup and view all the answers

What was Griffith's expectation when he injected heat-killed S-strain bacteria into mice?

<p>The mice would live with no bacteria in their blood. (D)</p> Signup and view all the answers

What was Griffith's surprising observation when he infected the mice with living type IIR bacteria and heat-killed type IIIS bacteria?

<p>The mice developed pneumonia and died. (B)</p> Signup and view all the answers

What was significant about the type IIIS bacteria observed by Griffith in the blood of the infected mice?

<p>They were virulent. (C)</p> Signup and view all the answers

What conclusion did Griffith draw from the fact that the infectivity of the type IIIS bacteria was heritable through several generations?

<p>Genetic material could be passed from bacteria to bacteria. (C)</p> Signup and view all the answers

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