Herpesviruses: Structure, Classification, and Diseases
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Questions and Answers

What is the size of a herpesvirus virion?

  • 300-350 nm in diameter
  • 50-100 nm in diameter
  • 100-150 nm in diameter
  • 200-250 nm in diameter (correct)

    • How many proteins are typically found in a herpesvirus virion?

  • More than 40 proteins (correct)
  • 20-25 proteins
  • 30-35 proteins
  • Less than 10 proteins

    • Which characteristic is NOT associated with herpesviruses?

  • Elicit an immediate immune response (correct)
  • Persist indefinitely in infected hosts
  • Establish latent infections
  • Frequently reactivated in immunosuppressed hosts

    • What type of infections do herpesviruses establish in their hosts?

    <p>Persistent infections with periodic reactivation</p> Signup and view all the answers

    Which virus belongs to the herpesvirus family?

    <p>Varicella zoster virus (VZV)</p> Signup and view all the answers

    What is a common characteristic of herpesviruses?

    <p>Establish latent infections</p> Signup and view all the answers

    What is the composition of the core of herpesviruses?

    <p>Double-stranded DNA</p> Signup and view all the answers

    Which genus of herpesviruses tends to establish latent infections in neurons?

    <p>Genus Simplex Virus: HSV</p> Signup and view all the answers

    Which herpesvirus genus is associated with massive enlargements of infected cells?

    <p>Cytomegalovirus genus: CMV</p> Signup and view all the answers

    Which function is associated with Human herpesviruses 6 and 7 (HHV-6 and HHV-7)?

    <p>Infecting T lymphocytes</p> Signup and view all the answers

    What is the main function of Real time PCR?

    <p>Faster than traditional PCR</p> Signup and view all the answers

    Which herpesvirus genus is known for fingerprinting of strains that allows epidemiologic tracing?

    <p>(HHV-6 and HHV-7)</p> Signup and view all the answers

    What does the tegument of herpesviruses refer to?

    <p>Amorphous and asymmetric structure between the capsid and envelope</p> Signup and view all the answers

    What is the base composition range of herpesviruses DNAs?

    <p>$31%$ to $75%$ (G+C)</p> Signup and view all the answers

    What is the main function of the viral envelope spikes in herpesviruses?

    <p>&quot;Infect&quot; host cells</p> Signup and view all the answers

    What is the size of a herpesvirus virion?

    <p>200-250 nm in diameter</p> Signup and view all the answers

    Which of the following is a characteristic of herpesvirus infections in humans?

    <p>They establish latent infections and can remain asymptomatic</p> Signup and view all the answers

    How many proteins are typically found in a herpesvirus virion?

    <p>More than 35 proteins</p> Signup and view all the answers

    What is a notable characteristic of herpesviruses' interaction with infected hosts?

    <p>They persist indefinitely in infected hosts</p> Signup and view all the answers

    What is the main function of the viral envelope in herpesviruses?

    <p>To contain viral glycoproteins for identification</p> Signup and view all the answers

    Which of the following is a common characteristic of herpesviruses?

    <p>They can cause cancer</p> Signup and view all the answers

    Which genus of herpesviruses is fast growing and tends to establish latent infections in neurons?

    <p>Genus Simplex Virus: HSV</p> Signup and view all the answers

    Which herpesvirus genus is known for massive enlargements of infected cells and latent infections in secretory glands and kidneys?

    <p>Cytomegalovirus genus: CMV</p> Signup and view all the answers

    What is the base composition range of herpesviruses DNAs?

    <p>40% to 70% (G+C)</p> Signup and view all the answers

    What is the size of a naked herpesvirus virion?

    <p>125 nm</p> Signup and view all the answers

    How many proteins are typically found in a herpesvirus virion?

    <p>30</p> Signup and view all the answers

    What is the main function of the viral envelope spikes in herpesviruses?

    <p>DNA synthesis</p> Signup and view all the answers

    What does the tegument of herpesviruses refer to?

    <p>Amorphous and asymmetric structure between the capsid and envelope</p> Signup and view all the answers

    What is the main function of Real time PCR?

    <p>To trace epidemiologic strains</p> Signup and view all the answers

    (1) Human herpesviruses 6 and 7 (HHV-6 and HHV-7) - display limited 30-50% sequence homology. What allows epidemiologic tracing of a given strain for these viruses?

    <p>&gt;10 viral envelope proteins</p> Signup and view all the answers

    How many different proteins are encoded by the genome for Human herpesviruses 6 and 7 (HHV-6 and HHV-7)?

    <p>&gt;100 different proteins encoded by the genome</p> Signup and view all the answers

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