Herpesviruses: Structure, Classification, and Diseases

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What is the size of a herpesvirus virion?

200-250 nm in diameter

How many proteins are typically found in a herpesvirus virion?

More than 40 proteins

Which characteristic is NOT associated with herpesviruses?

Elicit an immediate immune response

What type of infections do herpesviruses establish in their hosts?

Persistent infections with periodic reactivation

Which virus belongs to the herpesvirus family?

Varicella zoster virus (VZV)

What is a common characteristic of herpesviruses?

Establish latent infections

What is the composition of the core of herpesviruses?

Double-stranded DNA

Which genus of herpesviruses tends to establish latent infections in neurons?

Genus Simplex Virus: HSV

Which herpesvirus genus is associated with massive enlargements of infected cells?

Cytomegalovirus genus: CMV

Which function is associated with Human herpesviruses 6 and 7 (HHV-6 and HHV-7)?

Infecting T lymphocytes

What is the main function of Real time PCR?

Faster than traditional PCR

Which herpesvirus genus is known for fingerprinting of strains that allows epidemiologic tracing?

(HHV-6 and HHV-7)

What does the tegument of herpesviruses refer to?

Amorphous and asymmetric structure between the capsid and envelope

What is the base composition range of herpesviruses DNAs?

$31%$ to $75%$ (G+C)

What is the main function of the viral envelope spikes in herpesviruses?

"Infect" host cells

What is the size of a herpesvirus virion?

200-250 nm in diameter

Which of the following is a characteristic of herpesvirus infections in humans?

They establish latent infections and can remain asymptomatic

How many proteins are typically found in a herpesvirus virion?

More than 35 proteins

What is a notable characteristic of herpesviruses' interaction with infected hosts?

They persist indefinitely in infected hosts

What is the main function of the viral envelope in herpesviruses?

To contain viral glycoproteins for identification

Which of the following is a common characteristic of herpesviruses?

They can cause cancer

Which genus of herpesviruses is fast growing and tends to establish latent infections in neurons?

Genus Simplex Virus: HSV

Which herpesvirus genus is known for massive enlargements of infected cells and latent infections in secretory glands and kidneys?

Cytomegalovirus genus: CMV

What is the base composition range of herpesviruses DNAs?

40% to 70% (G+C)

What is the size of a naked herpesvirus virion?

125 nm

How many proteins are typically found in a herpesvirus virion?

30

What is the main function of the viral envelope spikes in herpesviruses?

DNA synthesis

What does the tegument of herpesviruses refer to?

Amorphous and asymmetric structure between the capsid and envelope

What is the main function of Real time PCR?

To trace epidemiologic strains

(1) Human herpesviruses 6 and 7 (HHV-6 and HHV-7) - display limited 30-50% sequence homology. What allows epidemiologic tracing of a given strain for these viruses?

>10 viral envelope proteins

How many different proteins are encoded by the genome for Human herpesviruses 6 and 7 (HHV-6 and HHV-7)?

>100 different proteins encoded by the genome

Explore the structure, classification, and diseases caused by herpesviruses in this comprehensive quiz. Learn about the properties of herpesviruses, including their virion structure and genome. Delve into an overview of herpesvirus diseases and specific infections in humans caused by Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV).

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