Herpesviruses: Structure, Classification, and Diseases
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Questions and Answers

What is the size of a herpesvirus virion?

  • 300-350 nm in diameter
  • 50-100 nm in diameter
  • 100-150 nm in diameter
  • 200-250 nm in diameter (correct)

How many proteins are typically found in a herpesvirus virion?

  • More than 40 proteins (correct)
  • 20-25 proteins
  • 30-35 proteins
  • Less than 10 proteins

Which characteristic is NOT associated with herpesviruses?

  • Elicit an immediate immune response (correct)
  • Persist indefinitely in infected hosts
  • Establish latent infections
  • Frequently reactivated in immunosuppressed hosts

What type of infections do herpesviruses establish in their hosts?

<p>Persistent infections with periodic reactivation (D)</p> Signup and view all the answers

Which virus belongs to the herpesvirus family?

<p>Varicella zoster virus (VZV) (B)</p> Signup and view all the answers

What is a common characteristic of herpesviruses?

<p>Establish latent infections (A)</p> Signup and view all the answers

What is the composition of the core of herpesviruses?

<p>Double-stranded DNA (B)</p> Signup and view all the answers

Which genus of herpesviruses tends to establish latent infections in neurons?

<p>Genus Simplex Virus: HSV (A)</p> Signup and view all the answers

Which herpesvirus genus is associated with massive enlargements of infected cells?

<p>Cytomegalovirus genus: CMV (D)</p> Signup and view all the answers

Which function is associated with Human herpesviruses 6 and 7 (HHV-6 and HHV-7)?

<p>Infecting T lymphocytes (B)</p> Signup and view all the answers

What is the main function of Real time PCR?

<p>Faster than traditional PCR (D)</p> Signup and view all the answers

Which herpesvirus genus is known for fingerprinting of strains that allows epidemiologic tracing?

<p>(HHV-6 and HHV-7) (A)</p> Signup and view all the answers

What does the tegument of herpesviruses refer to?

<p>Amorphous and asymmetric structure between the capsid and envelope (D)</p> Signup and view all the answers

What is the base composition range of herpesviruses DNAs?

<p>$31%$ to $75%$ (G+C) (C)</p> Signup and view all the answers

What is the main function of the viral envelope spikes in herpesviruses?

<p>&quot;Infect&quot; host cells (D)</p> Signup and view all the answers

What is the size of a herpesvirus virion?

<p>200-250 nm in diameter (A)</p> Signup and view all the answers

Which of the following is a characteristic of herpesvirus infections in humans?

<p>They establish latent infections and can remain asymptomatic (C)</p> Signup and view all the answers

How many proteins are typically found in a herpesvirus virion?

<p>More than 35 proteins (B)</p> Signup and view all the answers

What is a notable characteristic of herpesviruses' interaction with infected hosts?

<p>They persist indefinitely in infected hosts (D)</p> Signup and view all the answers

What is the main function of the viral envelope in herpesviruses?

<p>To contain viral glycoproteins for identification (D)</p> Signup and view all the answers

Which of the following is a common characteristic of herpesviruses?

<p>They can cause cancer (B)</p> Signup and view all the answers

Which genus of herpesviruses is fast growing and tends to establish latent infections in neurons?

<p>Genus Simplex Virus: HSV (B)</p> Signup and view all the answers

Which herpesvirus genus is known for massive enlargements of infected cells and latent infections in secretory glands and kidneys?

<p>Cytomegalovirus genus: CMV (A)</p> Signup and view all the answers

What is the base composition range of herpesviruses DNAs?

<p>40% to 70% (G+C) (B)</p> Signup and view all the answers

What is the size of a naked herpesvirus virion?

<p>125 nm (B)</p> Signup and view all the answers

How many proteins are typically found in a herpesvirus virion?

<p>30 (B)</p> Signup and view all the answers

What is the main function of the viral envelope spikes in herpesviruses?

<p>DNA synthesis (D)</p> Signup and view all the answers

What does the tegument of herpesviruses refer to?

<p>Amorphous and asymmetric structure between the capsid and envelope (A)</p> Signup and view all the answers

What is the main function of Real time PCR?

<p>To trace epidemiologic strains (A)</p> Signup and view all the answers

(1) Human herpesviruses 6 and 7 (HHV-6 and HHV-7) - display limited 30-50% sequence homology. What allows epidemiologic tracing of a given strain for these viruses?

<p>&gt;10 viral envelope proteins (D)</p> Signup and view all the answers

How many different proteins are encoded by the genome for Human herpesviruses 6 and 7 (HHV-6 and HHV-7)?

<p>&gt;100 different proteins encoded by the genome (C)</p> Signup and view all the answers

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