Hepatorenal Syndrome Learning Objectives

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6 Questions

What is the definition of Hepatorenal Syndrome (HRS-AKI)?

Renal impairment in the setting of liver disease

What is a common precipitating factor for Hepatorenal Syndrome (HRS-AKI)?

Systemic bacterial infections

Which major criterion is used for the diagnosis of Hepatorenal Syndrome (HRS-AKI)?

Cirrhosis with ascites and AKI

What role does vasodilation play in the pathophysiology of Hepatorenal Syndrome (HRS-AKI)?

Results in decreased vasodilator production

What treatment option is recommended to prevent hepatorenal syndrome in patients with elevated Serum Creatinine (SCr)?

Albumin 1g/kg up to 100 g/day

Why are kidneys still hypoperfused in Hepatorenal Syndrome (HRS-AKI) despite increased cardiac output and retention of Na/H2O?

Caused by overactive SNS and RAAS

Explore the pathophysiology, non-pharmacologic and pharmacologic management strategies, as well as primary and secondary prophylaxis for Hepatorenal Syndrome (HRS-AKI) in the context of cirrhosis complications. Learn about portal hypertension, varices, ascites, spontaneous bacterial peritonitis, hepatic encephalopathy, and hepatorenal syndrome.

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