Heparin Calculations Flashcards

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Questions and Answers

What is the rate in mL/hr for an infusion of 1,000 units/hr of heparin from a solution of 1,000 mL 0.45% NS with 25,000 units of heparin?

40 mL/hr

What is the dosage in units/hr when infusing D5 0.9% NS 1,000 mL with 25,000 units of heparin at 35 mL/hr?

875 units/hr

What is the dosage in units/hr for an infusion of D5W 1,000 mL with 25,000 units of heparin at 100 mL/hr?

25,000 units/hr

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Study Notes

Weight-based Heparin Protocol Calculations

  • Infusion Rate Calculation: For an order to infuse 1,000 units/hr of heparin from a solution of 1,000 mL 0.45% NS with 25,000 units of heparin, utilize the formula D/H * Q = x.

  • Example Calculation:

    • D = 1,000 units (desired dosage)
    • H = 25,000 units (available dosage)
    • Q = 100 mL (total volume)
    • Calculation: 1,000/25,000 * 100 = 40 mL/hr.
  • Dosage Calculation at a Specific Rate: When infusing D5 0.9% NS 1,000 mL with 25,000 units of heparin at a rate of 35 mL/hr, use H/D * Q = x.

  • Example Calculation:

    • H = 25,000 units
    • D = 1,000 mL (total volume)
    • Q = 35 mL/hr.
    • Calculation: 35/1,000 * 25,000 = 875 units/hr.

Additional Dosage Calculation Scenarios

  • High Rate Infusion: For infusing D5W 1,000 mL with 25,000 units of heparin at 100 mL/hr, again apply D/H * Q = x.
  • Example Calculation:
    • H = 25,000 units
    • D = 1,000 mL
    • Q = 100 mL/hr.
    • Calculation: 1,000 mL/25,000 * 100 = 25,000 units/hr.

General Formula Reference

  • Key Formulas:
    • D/H * Q = x (for finding the infusion rate)
    • H/D * Q = x (for calculating the dosage in units/hr)

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