Hemostasis Quiz
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Questions and Answers

What is hemostasis?

  • A physiological process that stops bleeding (correct)
  • A process that promotes bleeding
  • A type of blood vessel
  • A type of blood cell

    • What is the primary function of hemostasis?

  • To stop bleeding (correct)
  • To transport oxygen in the blood
  • To regulate body temperature
  • To produce hormones

    • What is the primary purpose of the clotting cascade in hemostasis? multiple

  • To form blood clots when a blood vessel is injured (correct)
  • To reconstruct damaged vessels and heal wounds
  • To dissolve unwanted clots naturally
  • To trigger inflammation within blood vessels

    • What is the role of fibrinolysis in hemostasis?

    <p>To dissolve unwanted clots naturally</p> Signup and view all the answers

    What is the process by which blood forms clots?

    <p>Coagulation</p> Signup and view all the answers

    What does anticoagulation refer to?

    <p>Prevention of blood clot formation</p> Signup and view all the answers

    What is the primary purpose of coagulation?

    <p>Formation of blood clots to prevent excessive bleeding</p> Signup and view all the answers

    Which process is characterized by the formation of a blood clot within a blood vessel?

    <p>Coagulation</p> Signup and view all the answers

    Which condition is associated with more coagulation than anticoagulation?

    <p>Thrombosis</p> Signup and view all the answers

    Which condition is typically associated with issues in the coagulation process rather than anticoagulation?

    <p>bleeding disorders</p> Signup and view all the answers

    What is the primary function of secondary hemostasis? multiple

    <p>Coagulation (fibrin formation)</p> Signup and view all the answers

    What occurs during primary hemostasis? multiple

    <p>Vasoconstriction</p> Signup and view all the answers

    What is the primary purpose of vascular spasm/vasoconstriction in response to a blood vessel injury?

    <p>To minimize blood loss by reducing blood flow to the injured area</p> Signup and view all the answers

    What happens when a blood vessel undergoes vasoconstriction?

    <p>The smooth muscle in the vessel walls contracts, causing a reduction in vessel diameter</p> Signup and view all the answers

    What is the effect of vasoconstriction on blood flow to the injured area?

    <p>It reduces blood flow to the injured area</p> Signup and view all the answers

    What is the effect of vascular spasm/vasoconstriction on small vessels/arterioles?

    <p>It doesn't work on small vessels/arterioles</p> Signup and view all the answers

    What is the primary function of coagulation?

    <p>Formation of a stable clot at the site of injury</p> Signup and view all the answers

    What initiates the extrinsic pathway of coagulation?

    <p>Tissue Factor (Thromboplastin)</p> Signup and view all the answers

    What is the conversion of fibrinogen into during coagulation?

    <p>Insoluble fibrin threads</p> Signup and view all the answers

    What is the primary role of nitric oxide (NO) and prostacyclin (PGI2) in the regulation of platelet adhesion and aggregation?

    <p>Inhibiting platelet adhesion and aggregation</p> Signup and view all the answers

    What is the origin of platelets?

    <p>Derived from megakaryocytes</p> Signup and view all the answers

    What is a characteristic of platelets?

    <p>Non-nucleated</p> Signup and view all the answers

    What is the primary function of Glycoprotein Ib (GP Ib) found on the surface of platelets?

    <p>Binding to von Willebrand factor (VWF)</p> Signup and view all the answers

    What is the source of von Willebrand factor (VWF) protein?

    <p>Endothelial cells</p> Signup and view all the answers

    Why is the binding between Glycoprotein Ib (GP Ib) and von Willebrand factor (VWF) important?

    <p>It is important in platelet aggregation</p> Signup and view all the answers

    What is the primary role of von Willebrand factor (VWF) in platelet aggregation?

    <p>Facilitating the binding of platelets through GP Ib</p> Signup and view all the answers

    What is the function of glycoprotein IIb/IIIa on the surface of platelets?

    <p>Enabling the binding of platelets to fibrinogen</p> Signup and view all the answers

    What is the significance of the binding between glycoprotein Ib (GP Ib) and von Willebrand factor (VWF) in the context of platelet function?

    <p>Initiating platelet adhesion and aggregation</p> Signup and view all the answers

    How are platelets activated when they come into contact with exposed collagen at the site of vascular injury?

    <p>They adhere or bind to it</p> Signup and view all the answers

    What is the significance of platelet adhesion to exposed collagen in the context of hemostasis?

    <p>It forms the initial plug at the site of injury</p> Signup and view all the answers

    What change in shape do activated platelets undergo?

    <p>From Spheroid to Irregular with Dense Filopodia</p> Signup and view all the answers

    What do activated platelets synthesis primarily ?

    <p>Thromboxane A2</p> Signup and view all the answers

    What do activated platelets display on their surface to create enzymatic complexes of clotting factors?

    <p>Phospholipids</p> Signup and view all the answers

    What is the primary change in shape that activated platelets undergo?

    <p>Change from spheroid to irregular with dense filopodia</p> Signup and view all the answers

    What is the primary role of Factor X in the coagulation cascade?

    <p>Activation of thrombin</p> Signup and view all the answers

    In which pathways of the coagulation cascade is Factor X involved?

    <p>Intrinsic and extrinsic pathways</p> Signup and view all the answers

    What is the primary function of most clotting factors in the coagulation cascade?

    <p>Initiating the formation of blood clots</p> Signup and view all the answers

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