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Questions and Answers
Which process is involved in hemostasis?
Which process is involved in hemostasis?
- Blood clotting (correct)
- Vasoconstriction
- Wound healing
- Platelet aggregation
What is the role of intact blood vessels in hemostasis?
What is the role of intact blood vessels in hemostasis?
- To prevent bleeding (correct)
- To initiate wound healing
- To secrete von Willebrand factor
- To promote blood clotting
Which molecules prevent blood clotting in intact blood vessels?
Which molecules prevent blood clotting in intact blood vessels?
- Heparin-like molecule and thrombomodulin
- Platelet plug
- Nitric oxide and prostacyclin (correct)
- Von Willebrand factor
What happens when the endothelium of a blood vessel is damaged?
What happens when the endothelium of a blood vessel is damaged?
How many major steps are involved in hemostasis?
How many major steps are involved in hemostasis?
Flashcards
Hemostasis
Hemostasis
The process of stopping blood flow, involving blood clotting.
Role of Intact Blood Vessels in Hemostasis
Role of Intact Blood Vessels in Hemostasis
Intact blood vessels prevent bleeding through the release of molecules like nitric oxide and prostacyclin.
Molecules Preventing Blood Clotting
Molecules Preventing Blood Clotting
Nitric oxide and prostacyclin prevent blood clotting inside intact blood vessels.
Damaged Endothelium
Damaged Endothelium
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Major Steps in Hemostasis
Major Steps in Hemostasis
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Study Notes
Hemostasis Process
- Hemostasis involves three main processes: blood coagulation, platelet plug formation, and vasoconstriction
Role of Intact Blood Vessels
- Intact blood vessels prevent blood clotting by producing molecules that inhibit clotting
- These molecules include thrombomodulin, heparan sulfate, and nitric oxide
Inhibition of Blood Clotting
- Thrombomodulin binds to thrombin, preventing it from clotting blood
- Heparan sulfate inhibits thrombin and clotting factor IXa
- Nitric oxide relaxes blood vessels and reduces platelet aggregation
Damage to Endothelium
- When the endothelium is damaged, collagen and tissue factor are exposed
- Platelets adhere to the exposed collagen, leading to platelet activation and aggregation
Steps of Hemostasis
- Hemostasis involves three major steps: vasospasm, platelet plug formation, and blood coagulation
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