Hemostasis and Coagulation Altering Medications Quiz

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What is the mechanism of action of VKA Warfarin?

Inhibit active vitamin K and dependent clotting factors II, VII, IX, and X and proteins C&S (correct)

Inhibit platelet aggregation

Inhibit P2Y12 receptors on platelets to prevent aggregation

Activate fibrin to reinforce clot formation

What is the primary indication for the use of IIB/IIIA Inhibitors (eptifibatide; tirofiban)?

Prophylaxis for ischemic stroke

Treatment of deep vein thrombosis

PCI in the setting of acute coronary syndrome (correct)

Prevention of myocardial infarction

What is the main side effect of P2Y12 Inhibitors (clopidogrel, prasugrel, ticagrelor)?

Thrombocytopenia

Gastrointestinal bleeding (correct)

Increased risk of ischemic stroke

Rash and dyspnea

What is the reason for holding ASA for 7 days before a procedure?

To allow time for platelet function to return to normal Signup and view all the answers

Which class of medications manipulates fibrin activation in the hemostasis process?

Anticoagulants Signup and view all the answers

What is the primary monitoring parameter for VKA Warfarin therapy?

International normalized ratio (INR) Signup and view all the answers

What is the main mechanism of action of Fibrinolytics?

Break down existing clots Signup and view all the answers

Which medication is a direct Xa Inhibitor?

Rivaroxaban Signup and view all the answers

What is the reversal agent for Dabigatran?

Idarucizumab Signup and view all the answers

What is the primary indication for the use of tPA (alteplase)?

Severe thrombotic disease Signup and view all the answers

What is the main mechanism of action of Heparin/LMWH (enoxaparin)?

Suppress coagulation by activating antithrombin Signup and view all the answers

What is the primary monitoring parameter for LMWH therapy?

PTT or anti-Xa Signup and view all the answers

Which medication is usually given if someone has Heparin Induced Thrombocytopenia (HIT) or is allergic to heparin?

Argatroban Signup and view all the answers

What is the Black Box Warning associated with Direct Xa Inhibitors?

Abruptly stopping leads to hypercoagulable state Signup and view all the answers

What is the reversal agent for tPA (alteplase)?

Aminocaproic acid Signup and view all the answers

Which medication irreversibly binds to platelets, necessitating a 7-day hold before a procedure?

Clopidogrel Signup and view all the answers

What is the primary mechanism of action of IIB/IIIA Inhibitors (eptifibatide; tirofiban)?

Inhibit binding of factor 8 & fibrinogen to platelets Signup and view all the answers

What is the main indication for the use of Fibrinolytics?

Break down clots Signup and view all the answers

Which medication class manipulates fibrin activation in the hemostasis process?

Anticoagulants Signup and view all the answers

What is the primary side effect of P2Y12 Inhibitors (clopidogrel, prasugrel, ticagrelor)?

Increase risk of bleeding Signup and view all the answers

What is the main mechanism of action of VKA Warfarin?

Inhibit active vitamin K and dependent clotting factors Signup and view all the answers

What is the primary monitoring parameter for VKA Warfarin therapy?

PT/PTT/INR Signup and view all the answers

What is the reversal agent for Heparin?

Protamine sulfate Signup and view all the answers

Which medication is a Direct Thrombin Inhibitor?

Dabigatran Signup and view all the answers

What is the primary contraindication for Fibrinolytic Therapy?

Intracranial hemorrhage Signup and view all the answers

What is the primary monitoring parameter for Direct Xa Inhibitors therapy?

CBC; renal; liver Signup and view all the answers

Which medication is given prior to PCI (percutaneous coronary intervention)?

Heparin Signup and view all the answers

What is the Black Box Warning associated with tPA (alteplase)?

Bleeding Signup and view all the answers

What is the primary indication for the use of Direct Xa Inhibitors?

DOACS (less bleeding risk than warfarin) Signup and view all the answers

What is the reversal agent for tPA (alteplase)?

Aminocaproic acid Signup and view all the answers

Which of the following is a contraindication for the use of LMWH?

Hemophilia Signup and view all the answers

What is the reversal agent for heparin?

Protamine sulfate Signup and view all the answers

Which of the following is a contraindication for the use of Direct Xa Inhibitors?

Pregnancy Signup and view all the answers

What is the mechanism of action of Fibrinolytic Therapy (tPA)?

Lysis of existing thrombus Signup and view all the answers

Which monitoring parameter is specifically associated with LMWH?

PTT or anti-Xa Signup and view all the answers

What is the reversal agent for dabigatran?

Idarucizumab Signup and view all the answers

Which of the following is an indication for the use of Direct Thrombin Inhibitors?

Atrial fibrillation Signup and view all the answers

What is the Black Box Warning associated with Direct Xa Inhibitors?

Abruptly stopping leads to hypercoagulable state Signup and view all the answers

Hemostasis and Coagulation Altering Medications Quiz

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Questions and Answers

What is the mechanism of action of VKA Warfarin?

What is the primary indication for the use of IIB/IIIA Inhibitors (eptifibatide; tirofiban)?

What is the main side effect of P2Y12 Inhibitors (clopidogrel, prasugrel, ticagrelor)?

What is the reason for holding ASA for 7 days before a procedure?

Which class of medications manipulates fibrin activation in the hemostasis process?

What is the primary monitoring parameter for VKA Warfarin therapy?

What is the main mechanism of action of Fibrinolytics?

Which medication is a direct Xa Inhibitor?

What is the reversal agent for Dabigatran?

What is the primary indication for the use of tPA (alteplase)?

What is the main mechanism of action of Heparin/LMWH (enoxaparin)?

What is the primary monitoring parameter for LMWH therapy?

Which medication is usually given if someone has Heparin Induced Thrombocytopenia (HIT) or is allergic to heparin?

What is the Black Box Warning associated with Direct Xa Inhibitors?

What is the reversal agent for tPA (alteplase)?

Which medication irreversibly binds to platelets, necessitating a 7-day hold before a procedure?

What is the primary mechanism of action of IIB/IIIA Inhibitors (eptifibatide; tirofiban)?

What is the main indication for the use of Fibrinolytics?

Which medication class manipulates fibrin activation in the hemostasis process?

What is the primary side effect of P2Y12 Inhibitors (clopidogrel, prasugrel, ticagrelor)?

What is the main mechanism of action of VKA Warfarin?

What is the primary monitoring parameter for VKA Warfarin therapy?

What is the reversal agent for Heparin?

Which medication is a Direct Thrombin Inhibitor?

What is the primary contraindication for Fibrinolytic Therapy?

What is the primary monitoring parameter for Direct Xa Inhibitors therapy?

Which medication is given prior to PCI (percutaneous coronary intervention)?

What is the Black Box Warning associated with tPA (alteplase)?

What is the primary indication for the use of Direct Xa Inhibitors?

What is the reversal agent for tPA (alteplase)?

Which of the following is a contraindication for the use of LMWH?

What is the reversal agent for heparin?

Which of the following is a contraindication for the use of Direct Xa Inhibitors?

What is the mechanism of action of Fibrinolytic Therapy (tPA)?

Which monitoring parameter is specifically associated with LMWH?

What is the reversal agent for dabigatran?

Which of the following is an indication for the use of Direct Thrombin Inhibitors?

What is the Black Box Warning associated with Direct Xa Inhibitors?

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