Hemostasis and Coagulation Pathways

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Questions and Answers

What is the main goal of the coagulation phase of hemostasis?

  • To activate smooth muscle cells.
  • To convert fibrinogen into fibrin. (correct)
  • To release chemicals like ADP and PDGF.
  • To form a platelet plug.

In hemostasis, what is the role of thrombin?

  • To activate prothrombinase. (correct)
  • To trigger platelet aggregation.
  • To form a platelet plug.
  • To convert fibrin into fibrinogen.

During clot retraction in hemostasis, what happens as the fibrin network grows?

  • Blood cells and platelets are trapped in the fibrous tangle. (correct)
  • Fibrinogen is converted into ADP.
  • Additional platelets are activated.
  • Blood cells are released from the clot.

What is the role of endothelins released by endothelial cells in hemostasis?

<p>Stimulate smooth muscle contraction (B)</p> Signup and view all the answers

During the platelet phase of hemostasis, what is the function of von Willebrand factor?

<p>Stimulates platelet adhesion to exposed surfaces (B)</p> Signup and view all the answers

What is the primary purpose of activated platelets in the coagulation process?

<p>Release clotting compounds that initiate fibrin formation (B)</p> Signup and view all the answers

During the vascular phase of hemostasis, what is the main function of the endothelial cells?

<p>Contraction and exposure of basement membrane (D)</p> Signup and view all the answers

Which of the following is NOT a function of platelets in the hemostasis process?

<p>Produce antibodies (A)</p> Signup and view all the answers

What is the main role of thrombin in the coagulation phase of hemostasis?

<p>Breaks down fibrinogen into fibrin (C)</p> Signup and view all the answers

Which phase of hemostasis involves the contraction of smooth muscle fibers in the vessel wall and lasts for about 30 minutes?

<p>Vascular phase (B)</p> Signup and view all the answers

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