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Hemostasis and Coagulation Pathways

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Questions and Answers

What is the main goal of the coagulation phase of hemostasis?

To activate smooth muscle cells.

To convert fibrinogen into fibrin. (correct)

To release chemicals like ADP and PDGF.

To form a platelet plug.

In hemostasis, what is the role of thrombin?

To activate prothrombinase. (correct)

To trigger platelet aggregation.

To form a platelet plug.

To convert fibrin into fibrinogen.

During clot retraction in hemostasis, what happens as the fibrin network grows?

Blood cells and platelets are trapped in the fibrous tangle. (correct)

Fibrinogen is converted into ADP.

Additional platelets are activated.

Blood cells are released from the clot.

What is the role of endothelins released by endothelial cells in hemostasis?

Stimulate smooth muscle contraction Signup and view all the answers

During the platelet phase of hemostasis, what is the function of von Willebrand factor?

Stimulates platelet adhesion to exposed surfaces Signup and view all the answers

What is the primary purpose of activated platelets in the coagulation process?

Release clotting compounds that initiate fibrin formation Signup and view all the answers

During the vascular phase of hemostasis, what is the main function of the endothelial cells?

Contraction and exposure of basement membrane Signup and view all the answers

Which of the following is NOT a function of platelets in the hemostasis process?

Produce antibodies Signup and view all the answers

What is the main role of thrombin in the coagulation phase of hemostasis?

Breaks down fibrinogen into fibrin Signup and view all the answers

Which phase of hemostasis involves the contraction of smooth muscle fibers in the vessel wall and lasts for about 30 minutes?

Vascular phase Signup and view all the answers