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Questions and Answers
What are the four mechanisms by which hemostasis is achieved?
Vascular constriction, formation of a platelet plug, formation of a blood clot, eventual growth of fibrous tissue into the blood clot
What are the characteristics of platelets?
They are minute discs formed in the bone marrow, don't have a nucleus, have a lifespan of 8 to 12 days, and are removed by the tissue macrophage system in the spleen
What is the normal concentration of platelets in the blood?
Between 150,000 and 300,000 per microliter
How do platelets change their characteristics when they come in contact with a damaged vascular surface?
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What is the role of vascular constriction in achieving hemostasis?
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What is the eventual outcome of the growth of fibrous tissue into the blood clot in hemostasis?
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What is the purpose of the platelet plug in the blood vessel?
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What is the role of tissue plasminogen activator (t-PA) in the process of fibrinolysis?
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What is the purpose of the Hess test in investigating bleeding disorders?
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How is bleeding time measured using Ivy's method?
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What does the Clotting Time (CT) measure?
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Name one condition that can cause excessive bleeding in humans.
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What is the term for an abnormal clot that develops in a blood vessel?
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What is the purpose of an emboli in the bloodstream?
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What initiates the clotting process in the blood?
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What is the role of fibrinolysis in the repair of the blood vessel?
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What is the normal range for bleeding time using Duke's method?
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What does the Hess test count as abnormal?
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