18 Questions
What is the major storage form of iron in the body?
Hemosiderin
What color does Hemosiderin pigment appear as?
Golden yellow-to-brown
What staining reaction with dye identifies Hemosiderin?
Blue color
In which medical condition would you expect to see Hemochromatosis?
Liver fibrosis
When is hemosiderosis primarily observed?
Within tissue macrophages
What does the Prussian blue reaction specifically indicate?
Presence of hemosiderin (iron)
Which type of excess iron accumulation is associated with tissue damage, scarring, and organ dysfunction?
Hemochromatosis
What staining reaction with dye results in a blue color when identifying Hemosiderin?
Prussian blue dye
In which type of iron accumulation is hemosiderin primarily found within tissue macrophages?
Hemosiderosis
What is the major storage form of iron represented by Hemosiderin pigment?
Ferritin micelles
What color does the Prussian blue reaction specifically indicate in relation to Hemosiderin?
Blue color
When there is a local or systemic excess of iron, what pigment accumulates in tissues?
Hemosiderin
What is the staining reaction with Prussian blue specific for, when identifying Hemosiderin?
Iron
In Hemochromatosis, where is the more extensive accumulation of hemosiderin primarily found?
Parenchymal cells
What organ dysfunction can be caused by the extensive accumulation of hemosiderin in Hemochromatosis?
Liver fibrosis
Which pigment represents aggregates of ferritin micelles within tissues?
Hemosiderin
What is the common pathological outcome associated with Hemosiderin accumulation?
Organ dysfunction
In which condition would hemosiderosis be primarily observed?
Sickle cell anemia
Learn about hemosiderin, a golden yellow-to-brown granular pigment which is one of the major storage forms of iron. Explore how hemosiderin accumulates in tissues, its staining reaction with Prussian blue dye, and the difference between hemosiderosis and hemochromatosis.
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