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Questions and Answers
What percentage of the hemoglobin molecule's mass is contributed by iron ions?
What percentage of the hemoglobin molecule's mass is contributed by iron ions?
What is a characteristic of biomolecules derived from hydrocarbons?
What is a characteristic of biomolecules derived from hydrocarbons?
What determines the physical-chemical properties of a biomolecule?
What determines the physical-chemical properties of a biomolecule?
What is the name of the biomolecule that carries acetyl groups in enzymatic reactions?
What is the name of the biomolecule that carries acetyl groups in enzymatic reactions?
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What are the major classes of biomolecules?
What are the major classes of biomolecules?
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What characteristic do proteins exhibit in terms of molecular masses?
What characteristic do proteins exhibit in terms of molecular masses?
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What is a common feature of lipids?
What is a common feature of lipids?
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What is the characteristic of amphiphilic lipids?
What is the characteristic of amphiphilic lipids?
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What is the characteristic of nucleic acids in terms of their composition?
What is the characteristic of nucleic acids in terms of their composition?
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What is a common feature of carbohydrates?
What is a common feature of carbohydrates?
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What is the term used to describe the building blocks of larger molecules called polymers?
What is the term used to describe the building blocks of larger molecules called polymers?
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What is the common name for a five-carbon sugar found in nucleotides?
What is the common name for a five-carbon sugar found in nucleotides?
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Which of the following is not classified as a small molecule?
Which of the following is not classified as a small molecule?
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What is the term used to describe the analysis of biological activity and detection of biological molecules?
What is the term used to describe the analysis of biological activity and detection of biological molecules?
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What is the Greek origin of the term 'polymers'?
What is the Greek origin of the term 'polymers'?
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What is the term for the collection of small organic molecules within cells?
What is the term for the collection of small organic molecules within cells?
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What is the molecular weight range of the relatively small compounds that are polymerized to form macromolecules?
What is the molecular weight range of the relatively small compounds that are polymerized to form macromolecules?
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What type of bond links amino acids to form proteins?
What type of bond links amino acids to form proteins?
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What is the term for the process of forming macromolecules from smaller compounds?
What is the term for the process of forming macromolecules from smaller compounds?
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What is the term for the number of polymerized units in a macromolecule?
What is the term for the number of polymerized units in a macromolecule?
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What is the estimated number of different proteins in the human body?
What is the estimated number of different proteins in the human body?
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What is the main product of photosynthesis?
What is the main product of photosynthesis?
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What percentage of total dry mass do proteins make up in cells?
What percentage of total dry mass do proteins make up in cells?
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What is the purpose of certain carbohydrates in cells?
What is the purpose of certain carbohydrates in cells?
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What is the estimated number of different protein types in nature?
What is the estimated number of different protein types in nature?
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What is the primary function of certain carbohydrates in connective tissues of animals?
What is the primary function of certain carbohydrates in connective tissues of animals?
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What is the estimated amount of CO2 converted into plant products each year through photosynthesis?
What is the estimated amount of CO2 converted into plant products each year through photosynthesis?
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What is a common feature of carbohydrates found in dietary staples?
What is a common feature of carbohydrates found in dietary staples?
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What is the role of certain carbohydrate polymers in joints?
What is the role of certain carbohydrate polymers in joints?
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What can proteins be isolated from?
What can proteins be isolated from?
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Which of the following elements are classified as bulk elements in biochemistry?
Which of the following elements are classified as bulk elements in biochemistry?
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What is the role of trace elements in biochemistry?
What is the role of trace elements in biochemistry?
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Which functional group is commonly found in biomolecules derived from hydrocarbons?
Which functional group is commonly found in biomolecules derived from hydrocarbons?
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What is a characteristic of carbon-containing compounds in biochemistry?
What is a characteristic of carbon-containing compounds in biochemistry?
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What determines the biochemical properties of a biomolecule?
What determines the biochemical properties of a biomolecule?
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What is a characteristic of small biomolecules found in the aqueous phase of cells?
What is a characteristic of small biomolecules found in the aqueous phase of cells?
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What are the building blocks of DNA?
What are the building blocks of DNA?
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What is a characteristic of macromolecules in cells?
What is a characteristic of macromolecules in cells?
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What is a feature of the universal set of small biomolecules in cells?
What is a feature of the universal set of small biomolecules in cells?
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What is a characteristic of certain small biomolecules in specialized cells or organisms?
What is a characteristic of certain small biomolecules in specialized cells or organisms?
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Study Notes
Vascular Plants and Metabolites
- Vascular plants produce secondary metabolites with specific biological roles, including scent production and physiological effects on humans.
- The metabolome consists of small organic molecules in cells, essential for metabolism and demonstrating evolutionary conservation of pathways.
Macromolecules in Cells
- Biomolecules typically exist as macromolecules, which are high molecular weight polymers formed from smaller monomers.
- Key macromolecules include proteins, nucleic acids, and polysaccharides, which result from the polymerization of compounds weighing less than 500 Da.
Protein Structure
- Proteins are polypeptides composed of amino acids linked by peptide bonds, structured in chains from N-terminal to C-terminal.
- They represent large biomolecules, essential for various cellular functions.
Cell Structure and Organization
- Cells contain supramolecular complexes, such as ribosomes and chromosomes, which are structured around macromolecules like DNA and proteins.
- DNA is made of nucleotides, serving as the basic subunit in genetic material.
Small Biomolecules in Cells
- The cytosol in all cells hosts 100 to 200 central metabolites critical for metabolic pathways.
- Composition includes common amino acids, nucleotides, sugars, and carboxylic acids, usually polar or charged and water-soluble.
Specialized Metabolites
- Certain cells or organisms may possess specific small biomolecules beyond the universal set found in all organisms.
Proteins: Abundance and Diversity
- Proteins constitute approximately 50% of the total dry mass of cells and tissues.
- The human body could contain around 100,000 different proteins; the exact number in nature remains undefined.
Carbohydrates and Photosynthesis
- Photosynthesis converts over 100 billion metric tons of CO2 and H2O annually into cellulose and other plant products.
- Carbohydrates, such as sugars and starches, are essential dietary staples and structural elements in various organisms.
Common Functional Groups in Biomolecules
- Biomolecules include hydrocarbons with various functional groups, which impart diverse chemical properties.
- Typical functional groups encompass alcohols, amines, carbonyls, and carboxylic acids.
Major Classes of Biomolecules
- Four major classes of biomolecules are vital for life: carbohydrates, lipids, proteins, and nucleic acids.
- Each class exhibits distinctive properties, such as molecular mass and isoelectric points.
Polysaccharides and Their Functions
- Polysaccharides are large carbohydrates formed from monosaccharides and can exist freely or as part of bioconjugates.
- They serve as structural and protective elements in cell walls and connective tissues.
Lipids Overview
- Lipids mainly consist of fatty acids and glycerol, being a diverse group soluble in chloroform.
- They include various classes, such as triglycerides and phospholipids, with unique amphiphilic properties.
Nucleic Acids Composition
- Nucleic acids, essential for life, are polymers of nucleotides, with DNA and RNA as their primary forms.
- A nucleotide comprises a nitrogenous base, a pentose sugar, and a phosphate group.
Biomolecular Classification
- Biomolecules are categorized into small molecules, which include lipids and carbohydrates, and larger structures called polymers.
- Polymers encompass proteins, nucleic acids, and polysaccharides, constructed from building blocks known as monomers.
Bioanalytical Chemistry Insights
- Bioanalytical chemistry focuses on analyzing biological activity and detecting biomolecules using varied scientific techniques.
- Key concepts involve recognizing functional groups in biomolecules, understanding green chemistry principles, and the importance of biosampling.
Essential Elements for Life
- Bulk elements serve as structural components of cells, while trace elements are crucial for specific protein functions, such as enzyme activity.
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Description
Explore the structure and function of hemoglobin, and learn about biomolecules, their derivation from hydrocarbons, and common functional groups. Understand the composition and properties of these essential biological molecules.