Podcast
Questions and Answers
What is the central metal ion in heme?
What is the central metal ion in heme?
- Magnesium
- Iron Fe2+ (correct)
- Zinc
- Copper
How many pyrrole rings are there in a heme molecule?
How many pyrrole rings are there in a heme molecule?
- 2
- 3
- 4 (correct)
- 5
Which of the following is NOT a hemoprotein?
Which of the following is NOT a hemoprotein?
- Hemoglobin
- Myoglobin
- Insulin (correct)
- Catalase
How many heme groups are present in hemoglobin?
How many heme groups are present in hemoglobin?
Which helix binds to the proximal histidine (F8) in hemoglobin?
Which helix binds to the proximal histidine (F8) in hemoglobin?
What type of bond stabilizes the heme group in the globin pocket?
What type of bond stabilizes the heme group in the globin pocket?
In hemoglobin, the sixth coordination site of iron binds to:
In hemoglobin, the sixth coordination site of iron binds to:
What is one key role of the apoprotein part of hemoglobin?
What is one key role of the apoprotein part of hemoglobin?
What is the Bohr effect in hemoglobin
What is the Bohr effect in hemoglobin
why does hemoglobin have a higher affinity for CO than O2?
why does hemoglobin have a higher affinity for CO than O2?
which amino acid in the polypeptide chain produces steric hindrance that produces CO binding affinity?
which amino acid in the polypeptide chain produces steric hindrance that produces CO binding affinity?
What is the main function of myoglobin?
What is the main function of myoglobin?
how many oxygen molecules can one hemoglobin molecule carry
how many oxygen molecules can one hemoglobin molecule carry
which has a higher affinity for oxygen, myoglobin or hemoglobin
which has a higher affinity for oxygen, myoglobin or hemoglobin
What percentage of adult hemoglobin is HbA?
What percentage of adult hemoglobin is HbA?
Where is hemoglobin primarily located?
Where is hemoglobin primarily located?
What is the structure of adult hemoglobin?
What is the structure of adult hemoglobin?
and hemoglobin oxygen binding is facilitated by which structural property?
and hemoglobin oxygen binding is facilitated by which structural property?
What type of protein structure does HbA1 have?
What type of protein structure does HbA1 have?
How many alpha chains are present in HbA1?
How many alpha chains are present in HbA1?
The two dims and hemoglobin are held together by
The two dims and hemoglobin are held together by
which of the following describes the quaternary structure of hemoglobin?
which of the following describes the quaternary structure of hemoglobin?
which of the following describes the quaternary structure of hemoglobin?
which of the following describes the quaternary structure of hemoglobin?
what happens to the hemoglobin molecule when it binds to oxygen?
what happens to the hemoglobin molecule when it binds to oxygen?
Which factor does not affect the oxygen binding ability of hemoglobin
Which factor does not affect the oxygen binding ability of hemoglobin
Which of the following stabilizes the T form of hemoglobin
Which of the following stabilizes the T form of hemoglobin
what is the role of 2,3- BPG in hemoglobin function?
what is the role of 2,3- BPG in hemoglobin function?
Hemoglobin exhibits cooperative binding, this means:
Hemoglobin exhibits cooperative binding, this means:
Hemoglobin exhibits cooperative binding, this means:
Hemoglobin exhibits cooperative binding, this means:
Which bonds are broken during the T to R transition in hemoglobin?
Which bonds are broken during the T to R transition in hemoglobin?
What molecule forms when liberated hydrogen ions bind with bicarbonate in the blood
What molecule forms when liberated hydrogen ions bind with bicarbonate in the blood
The Bohr effect facilitates the release of oxygen in tissues by
The Bohr effect facilitates the release of oxygen in tissues by
The Bohr effect facilitates the release of oxygen in tissues by
The Bohr effect facilitates the release of oxygen in tissues by
Carbaminohemoglobin is formed when CO2 binds to
Carbaminohemoglobin is formed when CO2 binds to
Carbon monoxide bonds through hemoglobin at the same site as
Carbon monoxide bonds through hemoglobin at the same site as
which form of hemoglobin is toxic and prevents oxygen release in tissues
which form of hemoglobin is toxic and prevents oxygen release in tissues
Which hemoglobin type is primarily present during the first three months of pregnancy?
Which hemoglobin type is primarily present during the first three months of pregnancy?
Glycated hemoglobin (HbA1c) reflects blood glucose levels over the past:
Glycated hemoglobin (HbA1c) reflects blood glucose levels over the past:
A HbA1c level greater than 6.5% typically indicates
A HbA1c level greater than 6.5% typically indicates
Where is myoglobin primarily found?
Where is myoglobin primarily found?
The alpha globin gene family is located on chromosome
The alpha globin gene family is located on chromosome
Which gene is expressed during the first three months of pregnancy
Which gene is expressed during the first three months of pregnancy
Hb Gower is formed by the combination of which chains?
Hb Gower is formed by the combination of which chains?
Sickle cell anemia is caused by a mutation in the gene coding for
Sickle cell anemia is caused by a mutation in the gene coding for
In sickle cell anemia, which amino acid is replaced in the beta globin chain?
In sickle cell anemia, which amino acid is replaced in the beta globin chain?
Individuals with sickle cell treat have
Individuals with sickle cell treat have
What amino acid is replaced by lysine in hemoglobin C (HbC) disease?
What amino acid is replaced by lysine in hemoglobin C (HbC) disease?
What is a key symptom of hemoglobin C (HbC) disease?
What is a key symptom of hemoglobin C (HbC) disease?
What happens in methemoglobinemia?
What happens in methemoglobinemia?
What type of thalassemia results in the formation of Hb Bart (y4) and Hb H (beta 4)?
What type of thalassemia results in the formation of Hb Bart (y4) and Hb H (beta 4)?
Which gene defect leads to alpha thalassemia major
Which gene defect leads to alpha thalassemia major
Why does a patient with beta thalassemia major appear normal at birth?
Why does a patient with beta thalassemia major appear normal at birth?
What is HbA2 composed of?
What is HbA2 composed of?
What is the common characteristic of thalassemia disorders?
What is the common characteristic of thalassemia disorders?
Which abnormal hemoglobin results from the replacement of histidine by tyrosine?
Which abnormal hemoglobin results from the replacement of histidine by tyrosine?
