Hematopoietic System Quiz
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Questions and Answers

Where is red (hematopoietic) bone marrow primarily found in adults?

  • Long bone diaphyses
  • Ends of long bones
  • Pelvis and ribs
  • Skull and vertebrae (correct)

Which type of hematopoietic tissue produces everything except lymphocytes?

  • Myeloid tissue (correct)
  • Lymphoid tissue
  • Yellow bone marrow
  • Red bone marrow

What is the function of hematopoietic tissue?

  • Produce lymphocytes and remove old lymphocytes
  • Produce new blood cells and remove old ones (correct)
  • Produce lymphocytes and remove old blood cells
  • Produce new blood cells and remove lymphocytes

Which process does the megakaryocyte nucleus undergo?

<p>Endomitosis (B)</p> Signup and view all the answers

How many copies of normal DNA can the megakaryocyte nucleus have?

<p>32 copies (B)</p> Signup and view all the answers

What is the main function of platelets?

<p>To form blood clots (C)</p> Signup and view all the answers

Where do B lymphocytes develop?

<p>Bone marrow (A)</p> Signup and view all the answers

Which cells are responsible for producing red blood cells, white blood cells, and platelets?

<p>Hematopoietic stem cells (B)</p> Signup and view all the answers

What type of collagen fibers are present in the bone marrow?

<p>Type III collagen fibers (C)</p> Signup and view all the answers

What are sinusoids?

<p>Thin-walled vessels with discontinuous endothelial cells (A)</p> Signup and view all the answers

What is the main function of erythrocytes?

<p>To produce hemoglobin (B)</p> Signup and view all the answers

Which process occurs in the megakaryocyte nucleus?

<p>Endomitosis (C)</p> Signup and view all the answers

What is the main function of platelets?

<p>Form blood clots (A)</p> Signup and view all the answers

Where do B lymphocytes develop?

<p>Bone marrow (A)</p> Signup and view all the answers

What is the function of granulocytes?

<p>Phagocytosis (A)</p> Signup and view all the answers

Which type of cells have a multilobed nucleus?

<p>Megakaryocytes (C)</p> Signup and view all the answers

How long does granulocyte maturation in the bone marrow take?

<p>A few weeks (A)</p> Signup and view all the answers

Where do T lymphocytes develop?

<p>Thymus (C)</p> Signup and view all the answers

What is the main function of erythrocytes?

<p>Transport oxygen (D)</p> Signup and view all the answers

What is the function of agranulocytes?

<p>Produce antibodies (C)</p> Signup and view all the answers

Where do B and T cells populate after leaving the bone marrow and thymus?

<p>Lymph nodes (B)</p> Signup and view all the answers

Which cells are present in the bone marrow?

<p>Fibroblasts, Macrophages, Adipocytes, Osteogenic cells, Endothelial cells (C)</p> Signup and view all the answers

What are the main jobs of erythrocytes?

<p>Make hemoglobin and form red blood cells with no nucleus (A)</p> Signup and view all the answers

How many red cells are released into the blood per second?

<p>2,500,000 (C)</p> Signup and view all the answers

What happens to the size of the red cell and its nucleus as it matures?

<p>Both decrease (B)</p> Signup and view all the answers

What happens to the chromatin in the nucleus as the red cell matures?

<p>It becomes more condensed (D)</p> Signup and view all the answers

What is the first stage of red cell maturation?

<p>Proerythroblast (D)</p> Signup and view all the answers

Which cells give rise to platelets?

<p>Megakaryocytes (D)</p> Signup and view all the answers

What is the size of megakaryocytes?

<p>Up to 100 µm (C)</p> Signup and view all the answers

What type of collagen fibers are present in the bone marrow?

<p>Type III collagen fibers (B)</p> Signup and view all the answers

What is the main function of platelets?

<p>To form blood clots (D)</p> Signup and view all the answers

Which type of hematopoietic tissue produces lymphocytes?

<p>Lymphoid tissue (A)</p> Signup and view all the answers

Where is yellow bone marrow primarily found in adults?

<p>Long bone diaphyses (A)</p> Signup and view all the answers

What is the function of granulocytes?

<p>Remove old blood cells (A)</p> Signup and view all the answers

What is the main function of erythrocytes?

<p>Carry oxygen (D)</p> Signup and view all the answers

Where is red (hematopoietic) bone marrow primarily found in adults?

<p>Skull (D)</p> Signup and view all the answers

What are the components of bone marrow stroma?

<p>Connective tissue network (C)</p> Signup and view all the answers

What is the function of platelets?

<p>Form blood clots (D)</p> Signup and view all the answers

What is the function of hematopoietic tissue?

<p>Produce new blood cells (A)</p> Signup and view all the answers

What is the developmental stages of erythropoiesis?

<p>Proerythroblast, basophilic erythroblast, polychromatophilic erythroblast, orthochromic erythroblast (C)</p> Signup and view all the answers

What is the developmental stages of granulopoiesis?

<p>Myeloblast, promyelocyte, myelocyte, metamyelocyte (B)</p> Signup and view all the answers

Flashcards

Red bone marrow location

Found in bone cavities like pelvis, ribs, and sternum in adults.

Yellow bone marrow location

Found in long bone shafts in adults.

Hematopoiesis

Process of blood cell production.

Blood cell types produced by hematopoietic cells

Red blood cells, white blood cells, and platelets, except lymphocytes.

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Megakaryocyte endomitosis

Nucleus duplicates DNA without cell division.

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Megakaryocyte DNA copies

Up to 64 copies of normal DNA.

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Platelet function

Form blood clots, stop bleeding.

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B lymphocyte development

Develop in the bone marrow.

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T lymphocyte development

Develop in the thymus.

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Hematopoietic stem cell function

Give rise to all blood cell types.

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Bone marrow stroma components

Fat cells, macrophages, reticular cells.

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Erythrocyte function

Carry oxygen from lungs to body tissues.

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Erythrocyte nucleus

Absent in mature erythrocytes.

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Erythropoiesis stages

Proerythroblast, basophilic, polychromatic, orthochromatic, reticulocyte, mature erythrocyte.

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Granulocyte nucleus

Multilobed nucleus.

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Granulocyte maturation time

10-14 days.

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Granulocyte function

Engulf and digest foreign particles, bacteria.

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Agranulocyte characteristic

Lack granules.

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Agranulocyte function

Produce antibodies.

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Bone marrow sinusoids

Special blood vessels in bone marrow.

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Study Notes

Bone Marrow Structure and Function

  • Red (hematopoietic) bone marrow is primarily found in the cavities of bones such as the pelvis, ribs, and sternum in adults.
  • Yellow bone marrow is primarily found in the shafts of long bones in adults.

Hematopoietic Tissue

  • Hematopoietic tissue produces all blood cells except lymphocytes.
  • Hematopoietic tissue is responsible for producing red blood cells, white blood cells, and platelets.

Megakaryocytes and Platelets

  • Megakaryocytes undergo endomitosis, a process in which the nucleus undergoes multiple rounds of DNA replication without cell division.
  • Megakaryocyte nuclei can have up to 64 copies of normal DNA.
  • Platelets are produced from megakaryocytes.
  • The main function of platelets is to form blood clots and stop bleeding.

Lymphocyte Development

  • B lymphocytes develop in the bone marrow.
  • T lymphocytes develop in the thymus.

Hematopoietic Stem Cells

  • Hematopoietic stem cells give rise to all types of blood cells, including red blood cells, white blood cells, and platelets.

Bone Marrow Components

  • Bone marrow stroma consists of various components, including fat cells, macrophages, and reticular cells.
  • Bone marrow also contains sinusoids, which are special blood vessels.

Erythrocytes

  • The main function of erythrocytes (red blood cells) is to carry oxygen from the lungs to the body's tissues.
  • Erythrocytes have no nucleus in their mature form.
  • The developmental stages of erythropoiesis are: proerythroblast, basophilic erythroblast, polychromatic erythroblast, orthochromatic erythroblast, reticulocyte, and mature erythrocyte.

Granulocytes

  • Granulocytes are a type of white blood cell that has a multilobed nucleus.
  • Granulocyte maturation in the bone marrow takes 10-14 days.
  • The function of granulocytes is to engulf and digest foreign particles and bacteria.

Agranulocytes

  • Agranulocytes are a type of white blood cell that lacks granules in their cytoplasm.
  • The function of agranulocytes is to produce antibodies to fight infections.

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Description

Test your knowledge on the hematopoietic system with this quiz. Learn about erythropoiesis and granulopoiesis, the differences between red and yellow marrow, bone marrow stroma, and colony forming units (CFUs).

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