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Questions and Answers
Where is red (hematopoietic) bone marrow primarily found in adults?
Where is red (hematopoietic) bone marrow primarily found in adults?
Which type of hematopoietic tissue produces everything except lymphocytes?
Which type of hematopoietic tissue produces everything except lymphocytes?
What is the function of hematopoietic tissue?
What is the function of hematopoietic tissue?
Which process does the megakaryocyte nucleus undergo?
Which process does the megakaryocyte nucleus undergo?
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How many copies of normal DNA can the megakaryocyte nucleus have?
How many copies of normal DNA can the megakaryocyte nucleus have?
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What is the main function of platelets?
What is the main function of platelets?
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Where do B lymphocytes develop?
Where do B lymphocytes develop?
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Which cells are responsible for producing red blood cells, white blood cells, and platelets?
Which cells are responsible for producing red blood cells, white blood cells, and platelets?
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What type of collagen fibers are present in the bone marrow?
What type of collagen fibers are present in the bone marrow?
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What are sinusoids?
What are sinusoids?
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What is the main function of erythrocytes?
What is the main function of erythrocytes?
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Which process occurs in the megakaryocyte nucleus?
Which process occurs in the megakaryocyte nucleus?
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What is the main function of platelets?
What is the main function of platelets?
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Where do B lymphocytes develop?
Where do B lymphocytes develop?
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What is the function of granulocytes?
What is the function of granulocytes?
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Which type of cells have a multilobed nucleus?
Which type of cells have a multilobed nucleus?
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How long does granulocyte maturation in the bone marrow take?
How long does granulocyte maturation in the bone marrow take?
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Where do T lymphocytes develop?
Where do T lymphocytes develop?
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What is the main function of erythrocytes?
What is the main function of erythrocytes?
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What is the function of agranulocytes?
What is the function of agranulocytes?
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Where do B and T cells populate after leaving the bone marrow and thymus?
Where do B and T cells populate after leaving the bone marrow and thymus?
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Which cells are present in the bone marrow?
Which cells are present in the bone marrow?
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What are the main jobs of erythrocytes?
What are the main jobs of erythrocytes?
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How many red cells are released into the blood per second?
How many red cells are released into the blood per second?
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What happens to the size of the red cell and its nucleus as it matures?
What happens to the size of the red cell and its nucleus as it matures?
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What happens to the chromatin in the nucleus as the red cell matures?
What happens to the chromatin in the nucleus as the red cell matures?
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What is the first stage of red cell maturation?
What is the first stage of red cell maturation?
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Which cells give rise to platelets?
Which cells give rise to platelets?
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What is the size of megakaryocytes?
What is the size of megakaryocytes?
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What type of collagen fibers are present in the bone marrow?
What type of collagen fibers are present in the bone marrow?
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What is the main function of platelets?
What is the main function of platelets?
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Which type of hematopoietic tissue produces lymphocytes?
Which type of hematopoietic tissue produces lymphocytes?
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Where is yellow bone marrow primarily found in adults?
Where is yellow bone marrow primarily found in adults?
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What is the function of granulocytes?
What is the function of granulocytes?
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What is the main function of erythrocytes?
What is the main function of erythrocytes?
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Where is red (hematopoietic) bone marrow primarily found in adults?
Where is red (hematopoietic) bone marrow primarily found in adults?
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What are the components of bone marrow stroma?
What are the components of bone marrow stroma?
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What is the function of platelets?
What is the function of platelets?
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What is the function of hematopoietic tissue?
What is the function of hematopoietic tissue?
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What is the developmental stages of erythropoiesis?
What is the developmental stages of erythropoiesis?
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What is the developmental stages of granulopoiesis?
What is the developmental stages of granulopoiesis?
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Study Notes
Bone Marrow Structure and Function
- Red (hematopoietic) bone marrow is primarily found in the cavities of bones such as the pelvis, ribs, and sternum in adults.
- Yellow bone marrow is primarily found in the shafts of long bones in adults.
Hematopoietic Tissue
- Hematopoietic tissue produces all blood cells except lymphocytes.
- Hematopoietic tissue is responsible for producing red blood cells, white blood cells, and platelets.
Megakaryocytes and Platelets
- Megakaryocytes undergo endomitosis, a process in which the nucleus undergoes multiple rounds of DNA replication without cell division.
- Megakaryocyte nuclei can have up to 64 copies of normal DNA.
- Platelets are produced from megakaryocytes.
- The main function of platelets is to form blood clots and stop bleeding.
Lymphocyte Development
- B lymphocytes develop in the bone marrow.
- T lymphocytes develop in the thymus.
Hematopoietic Stem Cells
- Hematopoietic stem cells give rise to all types of blood cells, including red blood cells, white blood cells, and platelets.
Bone Marrow Components
- Bone marrow stroma consists of various components, including fat cells, macrophages, and reticular cells.
- Bone marrow also contains sinusoids, which are special blood vessels.
Erythrocytes
- The main function of erythrocytes (red blood cells) is to carry oxygen from the lungs to the body's tissues.
- Erythrocytes have no nucleus in their mature form.
- The developmental stages of erythropoiesis are: proerythroblast, basophilic erythroblast, polychromatic erythroblast, orthochromatic erythroblast, reticulocyte, and mature erythrocyte.
Granulocytes
- Granulocytes are a type of white blood cell that has a multilobed nucleus.
- Granulocyte maturation in the bone marrow takes 10-14 days.
- The function of granulocytes is to engulf and digest foreign particles and bacteria.
Agranulocytes
- Agranulocytes are a type of white blood cell that lacks granules in their cytoplasm.
- The function of agranulocytes is to produce antibodies to fight infections.
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Description
Test your knowledge on the hematopoietic system with this quiz. Learn about erythropoiesis and granulopoiesis, the differences between red and yellow marrow, bone marrow stroma, and colony forming units (CFUs).